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Used
2021 Mercedes-Benz S-Class
for sale
near
Chagrin Falls, OH
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I was really pleased with my experience at Bohn Toyota my
I was really pleased with my experience at Bohn Toyota my local Dealership here in Marrero, Louisiana. I went in for service to my Vehicle. The individual who took care of me was Guillermo who communicated with me every step of the way. I?ve dealt with this Dealership before about a year ago and the results were the same.
Love my Mercedes
I have been driving Mercedes Benz s class vehicles for over 10 years, traded every 3-4 years and have been very happy, always have them serviced at the dealer, always received a loaner, no complaints.






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
It was a very good experience, the car was detailed and
It was a very good experience, the car was detailed and fully gassed waiting for us, paperwork was done before we got there so it was waiting for us to sign and drive 👍
An Absolute Dream
I have owned 6 S Class (SonderKlas) cars in my life and each and every single one has been problem free and a pure joy to own, drive, and admire. The 2021 S580 however.. Well this car is truly something special and not an incremental upgrade! This thing is crazy




Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Service
Had car ready before expected and service consultant when out of his way to get me a loaner picking car up was very fast and efficient
Luxury
Luxury at its best, you can’t get better than that with this price range. S 580 is the way to go, the 8 cylinders are so smooth yet so sporty. This car can be Rolls Royce luxury and lamborghini urus if it wants






Used
2021 Mercedes-Benz S-Class S 580
Vehicle information
Features
Reviews
Our car exceptional salesperson Zee Tyler was very
Our car exceptional salesperson Zee Tyler was very patient with my husband and I. Very professional and thorough on all questions. I highly recommend her for a great car buying experience. The Smiths.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I enjoyed working with Mr.
I enjoyed working with Mr. Watkins. He was professional and kind. He always made sure I was comfortable. Mr. Devon did the paperwork and he was no pressure. Overall I got what I needed and asked for. Makes me think I should have asked for more!! lol I am totally satisfied.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I was very satisfied with Zaid and the rest of the staff
I was very satisfied with Zaid and the rest of the staff at Twins Auto of Dublin. They have a great selection of used cars that tend be "higher end". Zaid was extremely knowledgeable about every brand and model. He wasn't overly pushy, which I appreciate. They were quick, painless, and fair when it came to negotiation and the financials.






Used
2021 Mercedes-Benz S-Class
Vehicle information
Features
Reviews
Will buy from them again.
Will buy from them again. The process from start to finish was easy and we’re happy with our purchase!!






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Mercedes Benz of Escondido
I was amazed by this dealership. From service to sales, everyone was so kind and helpful. I bought my 1st Mercedes here (2022 C300) and Patrick was there to assist me and make the experience the best one yet. Highly recommend this location for either getting your car serviced or buying a new Car!






Used
2021 Mercedes-Benz S-Class
Vehicle information
Features
Reviews
My experience was very pleasant, I found the vehicle I
My experience was very pleasant, I found the vehicle I wanted and I bought it, very easy process






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Professional service great product.
Professional service great product. Car was exactly as described delivery was on time in a closed trailer. Special thanks to Kane who helped me through the purchase.






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
MB of Santa Rosa is a model business.
MB of Santa Rosa is a model business. We just got a used vehicle there, and our experience was beyond positive. Liborio Rodriguez is an excellent sales manager. He was always available for follow-up questions, helped with all concerns, negotiated a great discount, and made the entire process easy and sufficient. I highly recommend MB of Santa Rosa. Their customer service is simply exemplary.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Excellent experience dealing with Eric.
Excellent experience dealing with Eric. I purchased remote and from initial contact to after delivery questions he was responsive and helpful. I would purchase again from this dealer!






Mercedes-Benz Certified
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I traded my 2014 ML350 and bought a 2024 GLE 350.
I traded my 2014 ML350 and bought a 2024 GLE 350. Service and sales were exceptional Brandon Gates really impressed us with his knowledge of the new software and controls. He provided very personalized service and we have reached out to him a few times since and got quick results. I highly recommend Chapman Mercedes on Grant in Tucson particularly Brandon at Sales and Lucky Luechtefeld as service representative.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
When you come to buy, look for Henry Rivalta.
When you come to buy, look for Henry Rivalta. He is the best! Very professional and detail oriented! The processes quick and fast 👍






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Recently purchased an Audi.
Recently purchased an Audi. Helpful, honest, and efficient crew. Jean worked with my credit and found the best financing options for my situation. Highly highly appreciate!






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Quick responses through text, emails, and phone calls.
Quick responses through text, emails, and phone calls. Professional and nice workers providing information & details.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
I highly recommend Everett Infiniti of Central Arkansas!
I highly recommend Everett Infiniti of Central Arkansas!! Matt, Easton, and Justin were so friendly! Not once did we feel any of them were pushy! Very helpful from start to finish! Matt met us at the door with a smile and within minutes had the exact car we were looking for pulled right up to the curb for us. He was very knowledgeable about the car and did not make us feel rushed at all! He also stayed late to go over all the bells and whistles on my car which meant a lot! Once we had found the perfect car, an Infinite QX 60 Autograph, Easton was super nice and welcoming and Justin did a great job on the finance end of things. It was a quick and speedy process! We couldn’t have been more pleased! Great people and company!! I am loving my car!!!






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
This was my first time buying a car without seeing it in
This was my first time buying a car without seeing it in person, and I was a little nervous at first. The team kept me updated with pictures and videos, and they handled the paperwork quickly and clearly. When the car arrived, it was just as described and in excellent shape. I'd absolutely do it again!






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Jason was upfront, honest and straight to the point.
Jason was upfront, honest and straight to the point. Didn?t play any games. I was offered a fair value for my trade in (unlike other dealerships). I was able to get my trade in and drive away in a brand new vehicle all under 3 hours.






Used
2021 Mercedes-Benz S-Class S 580 4MATIC
Vehicle information
Features
Reviews
Thanks Wayne, after four months after the sale, you still
Thanks Wayne, after four months after the sale, you still provide great service and was willing to stay late worked with me and my wife.
Mercedes-Benz S-Class prices by year
Model year | Average price | Deals |
---|---|---|
2026 Mercedes-Benz S-Class | $144,074 |
About the 2021 Mercedes-Benz S-Class
S 500 4MATIC shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- All-wheel Drive
- Combined MPG
- 24
- Transmission
- 9-Speed A/T
- Engine
- 429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid)

How much does the 2021 Mercedes-Benz S-Class cost?
The 2021 Mercedes-Benz S-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 S-Class is $64,859, with pricing starting at $49,885.
What is the MPG of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class offers up to 20 MPG in city driving and 29 MPG on the highway for a combined rating of 24 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz S-Class?
The 2021 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz S-Class reliable?
The 2021 Mercedes-Benz S-Class has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 S-Class owners.
Is the 2021 Mercedes-Benz S-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz S-Class.
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
100% of drivers recommend this car
- Comfort 5.0
- Interior 5.0
- Performance 5.0
- Value 4.7
- Exterior 5.0
- Reliability 5.0
S 500 (1 style)
Style |
---|
S 500 4MATIC Sedan |
Inventory price |
Starting at $109,800 |
Combined MPG |
24 |
Engine |
429.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
S 560 (2 styles)
Style | |
---|---|
S 560 Cabriolet | S 560 4MATIC Coupe |
Inventory price | |
Starting at $140,000 | Starting at $131,400 |
Combined MPG | |
20 | 20 |
Engine | |
463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) | 463.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline Fuel) |
S 580 (1 style)
Style |
---|
S 580 4MATIC Sedan |
Inventory price |
Starting at $116,300 |
Combined MPG |
20 |
Engine |
496.0-hp, 4.0-liter, 8 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz S-Class
Compare the 2021 Mercedes-Benz S-Class
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.