Compare 3 trims on the 2022 Mercedes-Benz E-Class

It’s important to carefully check the trims of the car you’re interested in to make sure that you’re getting the features you want, and aren’t overpaying for those you don’t want.

Our comparison will help you prioritize the trims that are right for you.

2022 Mercedes-Benz E-Class model details Shop 2022 Mercedes-Benz E-Class

E 350 (2 styles)

E 350 4MATIC Sedan	E 350 RWD Sedan
$57,450 Starting MSRP	$54,950 Starting MSRP
24 combined MPG MPG	26 combined MPG MPG
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) Engine	255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) Engine
9-Speed A/T Transmission	9-Speed A/T Transmission
All Wheel Drive Drivetrain	Rear Wheel Drive Drivetrain
Cardinal Red Metallic designo Magno Selenite Grey Nautical Blue Metallic designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Diamond White Metallic Obsidian Black Exterior Colors	Cardinal Red Metallic designo Magno Selenite Grey Nautical Blue Metallic designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Diamond White Metallic Obsidian Black Exterior Colors
5 Seating Capacity	5 Seating Capacity
View full specs	View full specs

Shop 2022 Mercedes-Benz E-Class E 350

E 450 (6 styles)

E 450 4MATIC All-Terrain Wagon	E 450 4MATIC Coupe	E 450 RWD Coupe	E 450 4MATIC Sedan	E 450 RWD Cabriolet	E 450 4MATIC Cabriolet
$68,400 Starting MSRP	$68,600 Starting MSRP	$66,100 Starting MSRP	$62,750 Starting MSRP	$73,250 Starting MSRP	$75,750 Starting MSRP
24 combined MPG MPG	24 combined MPG MPG	25 combined MPG MPG	25 combined MPG MPG	25 combined MPG MPG	24 combined MPG MPG
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) Engine	362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) Engine	362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) Engine	362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) Engine	362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) Engine	362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) Engine
9-Speed A/T Transmission	9-Speed A/T Transmission	9-Speed A/T Transmission	9-Speed A/T Transmission	9-Speed A/T Transmission	9-Speed A/T Transmission
All Wheel Drive Drivetrain	All Wheel Drive Drivetrain	Rear Wheel Drive Drivetrain	All Wheel Drive Drivetrain	Rear Wheel Drive Drivetrain	All Wheel Drive Drivetrain
Cardinal Red Metallic designo Magno Selenite Grey Nautical Blue Metallic designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Diamond White Metallic Obsidian Black Exterior Colors	Moonlight White designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Rubellite Red Patagonia Red Obsidian Black Emerald Green Metallic Sterling Blue Metallic Exterior Colors	Moonlight White designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Rubellite Red Patagonia Red Obsidian Black Emerald Green Metallic Sterling Blue Metallic Exterior Colors	Cardinal Red Metallic designo Magno Selenite Grey Nautical Blue Metallic designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Diamond White Metallic Obsidian Black Exterior Colors	Moonlight White designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Rubellite Red Patagonia Red Obsidian Black Emerald Green Metallic Sterling Blue Metallic Exterior Colors	Moonlight White designo Selenite Grey Graphite Grey Metallic Solid Gold Metallic Black Polar White Whistler White Rubellite Red Patagonia Red Obsidian Black Emerald Green Metallic Sterling Blue Metallic Exterior Colors
7 Seating Capacity	4 Seating Capacity	4 Seating Capacity	5 Seating Capacity	4 Seating Capacity	4 Seating Capacity
View full specs	View full specs	View full specs	View full specs	View full specs	View full specs

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Compare 3 trims on the 2022 Mercedes-Benz E-Class

E 350 (2 styles)

E 450 (6 styles)

Research the 2022 Mercedes-Benz E-Class