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Used
2021 Mercedes-Benz E-Class
for sale
near me
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Certified
2021 Mercedes-Benz E-Class E 450
Vehicle information
Features
Reviews
Experience buying my new Ford Ranger at Germain Ford was
Experience buying my new Ford Ranger at Germain Ford was very good. Salesman Jean wasextremely nice to work with. Had a little delivery delay due to a part recall, but other than that, experience was fine. I ansolutely love the Ranger compared to my Honda Ridgeline!!!!!!
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰
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2023 Mercedes-Benz E-Class E 350 4MATIC
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Mercedes-Benz Certified
2022 Mercedes-Benz E-Class E 350 4MATIC
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Used
2023 Mercedes-Benz E-Class 4MATIC
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Mercedes-Benz E-Class prices by year
Model year | Average price | Deals |
---|---|---|
2026 Mercedes-Benz E-Class | $76,815 | 1 Good deal |
2025 Mercedes-Benz E-Class | $70,494 | 61 Great deals |
2024 Mercedes-Benz E-Class | $61,220 | 8 Great deals |
2023 Mercedes-Benz E-Class | $52,943 | 40 Great deals |
2022 Mercedes-Benz E-Class | $40,302 | 47 Great deals |
2020 Mercedes-Benz E-Class | $29,368 | 27 Great deals |
2019 Mercedes-Benz E-Class | $27,238 | 49 Great deals |
2018 Mercedes-Benz E-Class | $24,646 | 32 Great deals |
2017 Mercedes-Benz E-Class | $20,191 | 39 Great deals |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $37,109, with pricing starting at $21,250.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
Style | |
---|---|
E 350 RWD Sedan | E 350 4MATIC Sedan |
Inventory price | |
Starting at $54,250 | Starting at $56,750 |
Combined MPG | |
25 | 25 |
Engine | |
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
Style | |||||
---|---|---|---|---|---|
E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
Inventory price | |||||
Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
Combined MPG | |||||
25 | 24 | 25 | 26 | 26 | 25 |
Engine | |||||
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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Research the 2021 Mercedes-Benz E-Class
Compare the 2021 Mercedes-Benz E-Class
2021 Mercedes-Benz E-Class by popular city
-
2021 Mercedes-Benz E-Class in Los Angeles, CA
1 Great Deal out of 11 listings starting at $26,400
-
2021 Mercedes-Benz E-Class in New York, NY
3 Great Deals out of 30 listings starting at $21,250
Mercedes-Benz E-Class trims
-
Mercedes-Benz E-Class 2021 E 350
8 Great Deals out of 94 listings starting at $24,598
-
Mercedes-Benz E-Class 2021 E 350 4MATIC
4 Great Deals out of 51 listings starting at $21,250
-
Mercedes-Benz E-Class 2021 E 450 4MATIC
5 Great Deals out of 43 listings starting at $29,198
-
Mercedes-Benz E-Class 2021 E 450
4 Great Deals out of 26 listings starting at $30,595
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.