Skip to main content
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed
Skip to Filters
  • $49,607

    MSRP $49,607

    Est. $896/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $56,422

    MSRP $56,422

    Est. $1,020/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $61,642

    MSRP $61,642

    Est. $1,114/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $49,707

    MSRP $49,707

    Est. $898/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $55,757

    MSRP $55,757

    Est. $1,008/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $55,799

    MSRP $55,799

    Est. $1,008/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $50,399

    MSRP $50,399

    Est. $911/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $59,108

    MSRP $59,108

    Est. $1,068/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $50,227

    MSRP $50,227

    Est. $908/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $55,827

    MSRP $55,827

    Est. $1,009/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $59,367

    MSRP $59,367

    Est. $1,073/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $58,797

    MSRP $58,797

    Est. $1,063/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • Not Priced

    Est. $0/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $59,897

    MSRP $59,897

    Est. $1,082/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $59,488

    MSRP $59,488

    Est. $1,075/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • $58,797

    MSRP $58,797

    Est. $1,063/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
    Quick view
  • Silver 2026 Lexus IS 350 F-SportSilver 2026 Lexus IS 350 F-SportSilver 2026 Lexus IS 350 F-SportSilver 2026 Lexus IS 350 F-SportSilver 2026 Lexus IS 350 F-SportSilver 2026 Lexus IS 350 F-Sport

    $52,998

    2,399 mi.
    Est. $958/mo

    CarMax Oxnard

    4.5
    Check Availability
    $1,799 delivery to Greenville, SC (5 mi)
    Quick view
  • Iridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 Base

    $55,654

    MSRP $53,053

    Est. $1,006/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $61,485

    MSRP $58,884

    Est. $1,111/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $57,659

    MSRP $55,058

    Est. $1,042/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $64,243

    MSRP $61,642

    Est. $1,161/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • Iridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 BaseIridium 2026 Lexus IS 350 Base

    $56,045

    MSRP $53,444

    Est. $1,013/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $61,485

    MSRP $58,884

    Est. $1,111/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $61,774

    MSRP $59,173

    Est. $1,116/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • White 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 BaseWhite 2026 Lexus IS 350 Base

    $61,215

    MSRP $58,614

    Est. $1,106/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • caviar 2026 Lexus IS 350 Basecaviar 2026 Lexus IS 350 Basecaviar 2026 Lexus IS 350 Basecaviar 2026 Lexus IS 350 Basecaviar 2026 Lexus IS 350 Basecaviar 2026 Lexus IS 350 Base

    $57,345

    MSRP $54,744

    Est. $1,036/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view
  • Cloudburst Gray 2026 Lexus IS 350 BaseCloudburst Gray 2026 Lexus IS 350 BaseCloudburst Gray 2026 Lexus IS 350 BaseCloudburst Gray 2026 Lexus IS 350 BaseCloudburst Gray 2026 Lexus IS 350 BaseCloudburst Gray 2026 Lexus IS 350 Base

    $63,134

    MSRP $60,533

    Est. $1,141/mo

    Jim Hudson Lexus Augusta

    4.8
    Check Availability
    Martinez, GA (96 mi)
    Quick view

About the 2026 Lexus IS 350

Basics

F SPORT Design shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
22
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2026 Lexus IS 350
FAQs

How much does the 2026 Lexus IS 350 cost?

The 2026 Lexus IS 350 price depends on trim level and optional features. Prices typically start at $45,500 and go as high as $49,950 for fully loaded models.

What is the MPG of the 2026 Lexus IS 350?

The 2026 Lexus IS 350 offers up to 19 MPG in city driving and 27 MPG on the highway for a combined rating of 22 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2026 Lexus IS 350?

The 2026 Lexus IS 350 compares to and/or competes against the following vehicles:


Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $47,950 Starting at $49,950
Combined MPG
22 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

IS 350 F SPORT Design (2 styles)

Style
IS 350 F SPORT Design RWD IS 350 F SPORT Design AWD
Inventory price
Starting at $45,500 Starting at $47,500
Combined MPG
22 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Skip to Listings
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed