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  • Ultra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT Handling

    $41,952

    40,431 mi.
    Est. $778/mo

    Lexus of Cerritos

    4.7
    Check Availability
    Cerritos, CA (8 mi)

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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $34,208

    $790
    45,984 mi.
    Est. $634/mo

    Wondries Toyota

    4.6
    Check Availability
    Alhambra, CA (22 mi)
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  • Caviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT Handling

    $34,394

    79,562 mi.
    Est. $638/mo

    Fletcher Jones Motorcars

    4.4
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    Newport Beach, CA (13 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $30,999

    73,643 mi.
    Est. $575/mo

    California Motors Direct

    4.2
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    Santa Ana, CA (9 mi)
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  • White 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 L

    $36,998

    45,338 mi.
    Est. $686/mo

    CarMax Irvine

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    Irvine, CA (19 mi)
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  • White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350

    $38,998

    43,367 mi.
    Est. $723/mo

    CarMax Irvine

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    Irvine, CA (19 mi)
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  • Nebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 Premium

    $41,297

    33,849 mi.
    Est. $766/mo

    STG Auto Group of Bellflower

    2.4
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    Bellflower, CA (11 mi)
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  • Nightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 Base

    $31,599

    60,485 mi.
    Est. $586/mo

    California Motor Trade 3

    3.2
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    Norco, CA (26 mi)
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  • $35,971

    63,066 mi.
    Est. $667/mo

    South County Lexus

    4.0
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    Mission Viejo, CA (26 mi)
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  • $47,988

    40,913 mi.
    Est. $890/mo

    Lexus of Glendale

    4.8
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    Glendale, CA (28 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $39,998

    29,829 mi.
    Est. $742/mo

    CarMax Stockton

    4.8
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    $149 delivery to Buena Park, CA (5 mi)
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  • Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350

    $33,998

    55,625 mi.
    Est. $630/mo

    CarMax Canoga Park

    4.6
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    Free delivery to Buena Park, CA (5 mi)
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  • Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350

    $33,998

    55,625 mi.
    Est. $630/mo

    CarMax Canoga Park

    4.6
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    Canoga Park, CA (45 mi)
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  • Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350

    $35,998

    39,099 mi.
    Est. $667/mo

    CarMax Palm Desert

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    Palm Desert, CA (93 mi)
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  • $27,288

    87,123 mi.
    Est. $506/mo

    Toyota of Riverside

    4.7
    Check Availability
    Riverside, CA (35 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $61,300 2 Good deals
2025 Lexus RX 350 $53,167 10 Great deals
2024 Lexus RX 350 $49,678 28 Good deals
2023 Lexus RX 350 $46,254 32 Good deals
2017 Lexus RX 350 $23,442 7 Good deals

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $36,082, with pricing starting at $25,172.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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