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  • Ultra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT Appearance

    $39,495

    36,802 mi.
    Est. $673/mo

    Automotive Avenues Sewell

    5.0
    Check Availability
    Washington Township, NJ (23 mi)

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  • Brown 2021 Lexus RX 350 F SPORT AppearanceBrown 2021 Lexus RX 350 F SPORT AppearanceBrown 2021 Lexus RX 350 F SPORT AppearanceBrown 2021 Lexus RX 350 F SPORT AppearanceBrown 2021 Lexus RX 350 F SPORT AppearanceBrown 2021 Lexus RX 350 F SPORT Appearance

    $31,529

    81,201 mi.
    Est. $538/mo

    Pointe GMC

    4.0
    Check Availability
    Penns Grove, NJ (5 mi)
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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $38,972

    36,385 mi.
    Est. $664/mo

    GENESIS OF CONSHOHOCKEN

    5.0
    Check Availability
    CONSHOHOCKEN, PA (28 mi)
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  • $32,992

    79,319 mi.
    Est. $562/mo

    Union Park Honda BMW Buick GMC Volvo Car

    2.4
    Check Availability
    Wilmington, DE (2 mi)
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  • $39,000

    40,171 mi.
    Est. $665/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (2 mi)
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  • Gray 2021 Lexus RX 350 F-SPORT HandlingGray 2021 Lexus RX 350 F-SPORT HandlingGray 2021 Lexus RX 350 F-SPORT HandlingGray 2021 Lexus RX 350 F-SPORT HandlingGray 2021 Lexus RX 350 F-SPORT HandlingGray 2021 Lexus RX 350 F-SPORT Handling

    $45,998

    $1K
    21,720 mi.
    Est. $784/mo

    CarMax Greensboro

    Check Availability
    $149 delivery to Newark, DE (11 mi)
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  • Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350

    $33,998

    84,521 mi.
    Est. $580/mo

    CarMax Dayton

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    $349 delivery to Newark, DE (11 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $38,996

    $1K
    21,459 mi.
    Est. $665/mo

    Jones Preowned Superstore

    3.1
    Check Availability
    Fallston, MD (48 mi)
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  • White Pearl 2021 Lexus RX 350 BaseWhite Pearl 2021 Lexus RX 350 BaseWhite Pearl 2021 Lexus RX 350 BaseWhite Pearl 2021 Lexus RX 350 BaseWhite Pearl 2021 Lexus RX 350 BaseWhite Pearl 2021 Lexus RX 350 Base

    $39,998

    37,370 mi.
    Est. $682/mo

    Bobby Rahal Lexus of Lancaster County

    4.9
    Check Availability
    Ephrata, PA (45 mi)
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  • Nebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 Base

    $29,787

    $600
    86,699 mi.
    Est. $508/mo

    Elite Acura

    4.9
    Check Availability
    Maple Shade, NJ (34 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $64,538 1 Good deal
2023 Lexus RX 350 $47,643 7 Good deals

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $36,156, with pricing starting at $25,172.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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