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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $40,500

    $1K
    38,962 mi.
    Est. $750/mo

    Lexus of Freeport

    4.7
    Check Availability
    Rockville Centre, NY (11 mi)

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  • White 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 L

    $42,998

    38,371 mi.
    Est. $796/mo

    CarMax Smithtown

    Check Availability
    Smithtown, NY (19 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $41,998

    19,563 mi.
    Est. $778/mo

    New Country Lexus of Great Neck

    4.5
    Check Availability
    Great Neck, NY (13 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $36,842

    76,205 mi.
    Est. $682/mo

    Stream Auto Outlet Valley Stream

    4.3
    Check Availability
    Valley Stream, NY (13 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $41,800

    29,267 mi.
    Est. $774/mo

    MajorWorld Chevy

    3.9
    Check Availability
    Long Island City, NY (23 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $44,943

    19,146 mi.
    Est. $832/mo

    BMW of Freeport

    4.9
    Check Availability
    Freeport, NY (9 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $40,000

    31,054 mi.
    Est. $741/mo

    Porsche Greenwich

    4.7
    Check Availability
    Greenwich, CT (22 mi)
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  • Caviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWD

    $28,995

    79,356 mi.
    Est. $537/mo

    Victory Mitsubishi

    3.4
    Check Availability
    Bronx, NY (21 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT Appearance

    $35,990

    33,683 mi.
    Est. $667/mo

    Auto Lux

    3.4
    Check Availability
    Elmont, NY (11 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $33,990

    74,362 mi.
    Est. $629/mo

    Auto Lux

    3.4
    Check Availability
    Elmont, NY (11 mi)
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  • Silver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 Base

    $29,995

    82,756 mi.
    Est. $555/mo

    Power Motors NYC Inc

    3.7
    Check Availability
    Bellerose, NY (13 mi)
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  • White 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 L

    $46,998

    14,480 mi.
    Est. $870/mo

    CarMax East Meadow

    Check Availability
    East Meadow, NY (5 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $35,998

    55,743 mi.
    Est. $667/mo

    New Country Lexus of Great Neck

    4.5
    Check Availability
    Great Neck, NY (13 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT Appearance

    $37,795

    $500
    29,304 mi.
    Est. $700/mo

    112 Off Lease

    2.1
    Check Availability
    Medford, NY (26 mi)
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  • $38,000

    52,248 mi.
    Est. $704/mo

    DARCARS Lexus of Greenwich

    4.6
    Check Availability
    Greenwich, CT (21 mi)
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  • Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350

    $43,998

    $1K
    30,199 mi.
    Est. $815/mo

    CarMax Winchester

    Check Availability
    $99 delivery to East Meadow, NY (5 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $34,975

    75,146 mi.
    Est. $648/mo

    Bob Johnson Used

    4.0
    Check Availability
    $399 delivery from Rochester, NY (266 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $39,577

    $300
    38,322 mi.
    Est. $733/mo

    Salerno Duane Chrysler Jeep Dodge Ram

    4.6
    Check Availability
    Summit, NJ (46 mi)
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  • Red 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 Base

    $35,500

    38,564 mi.
    Est. $657/mo

    G-Motors of Old Bridge

    4.4
    Check Availability
    Old Bridge, NJ (48 mi)
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  • Grecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT Appearance

    $42,990

    22,302 mi.
    Est. $796/mo

    Bomnin Chevrolet Buick GMC Nanuet

    4.7
    Check Availability
    Nanuet, NY (37 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT Appearance

    $37,194

    $298
    49,712 mi.
    Est. $689/mo

    Carz4Us Pine Brook

    3.5
    Check Availability
    Pine Brook, NJ (46 mi)
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  • Nightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT Appearance

    $41,353

    26,740 mi.
    Est. $766/mo

    Tri-County Lexus

    4.8
    Check Availability
    Little Falls, NJ (39 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $41,621

    27,410 mi.
    Est. $771/mo

    Tri-County Lexus

    4.8
    Check Availability
    Little Falls, NJ (39 mi)
    Quick view

Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $62,815
2025 Lexus RX 350 $53,642 5 Great deals
2024 Lexus RX 350 $48,254 21 Good deals
2023 Lexus RX 350 $45,788 23 Good deals
2017 Lexus RX 350 $24,259 4 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $40,361, with pricing starting at $27,450.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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