Save your search and get notified when new inventory arrives.
Contact seller
Customize your budget
Est. max vehicle price based on your desired monthly budget (...% APR*. and ...% sales tax)
$...*
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
About your privacy: Cars.com is asking for your ZIP and credit rating because it helps us to make an educated guess at your sales tax and loan interest. These two factors can greatly change your monthly payment.
Used
2022 Lexus RX 350
for sale
near
Gateway, FL
9 matches
30 miles from 33973
Be the first to know!
Est.
$400
/mo*
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Vehicle information
Ext. color: White
Int. color: CREAM
Drivetrain: Rear-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Gas
Stock #: 27892662
VIN: 2T2HZMAA2NC250145
Features
Convenience:
Heated Steering Wheel, Navigation System, Remote Start
Entertainment:
Bluetooth®, HomeLink, Satellite Radio, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Backup Camera, Blind Spot Monitor, Lane Departure Warning, Rain Sensing Wipers
Seating:
Leather Seats, Memory Seat
Reviews
CarMax Ft. Myers review
Sold my late Father's car
This company bends over backwards to accommodate their customers. Every time I see one of their commercials on tv I get a good feeling becuse of my experience.
2022 Lexus RX 350 review
Love this car.
Love this car. Sitting in the driver’s seat is so comfortable. Silky smooth engine. Rides so nice and quiet. We have looked for this color Grecian water for a long time. Wanted no newer than a 2022 because we didn’t want the 4 cylinder. The 3.5 V6 runs so smooth. Would definitely recommend the purchase of this SUV.
Used
2022 Lexus RX 350 Premium Plus
25,896 mi.
$39,081
Volvo Cars Fort Myers
Vehicle information
Ext. color: Nori Green Pearl
Int. color: Black
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: VFP234398
VIN: 2T2HZMAA6NC234398
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Volvo Cars Fort Myers review
On August 03, 2025 I submitted an email inquiry to Volvo
On August 03, 2025 I submitted an email inquiry to Volvo Cars Fort Myers as to the availability of a 2025 XC40 with 5912 miles listed for sale. I received an immediately response via email by Sales Representative "Arley Ricardo" who was warm, engaging and displayed subject matter expertise relative to the vehicle in question and dealership. Arley was organized in his demeanor during our entire interaction and routinely conveyed transparency regarding pricing and financing options. After a few days of effective back and forth communication we reached a purchase agreement on August 06, 2025. During the entire process, Arley and the staff of "Volvo Cars Fort Myers" provided "Superior Customer Service," cemented with courtesy, professionalism and respect: An experience that certainly merits a, ******** 5 STAR RATING *********
2022 Lexus RX 350 Premium Plus review
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own
Used
2022 Lexus RX 350 Base
33,877 mi.
$34,824
$3,104 price drop
Naples Mazda
Vehicle information
Ext. color: Mica
Int. color: Birch
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: C235350
VIN: 2T2AZMAA3NC235350
Features
Convenience:
Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats
Reviews
Naples Mazda review
Great service Juan!!
Very pleased with Juan Guerrero’s service, we had issues adding the car to our insurance but he was amazingly patient with all of that. I will definitely recommend anyone to go and see him! However I can not say the same about the finance person, he was making rude comments about my job and not very pleasant.
2022 Lexus RX 350 Base review
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.
Used
2022 Lexus RX 350 F SPORT Handling
18,434 mi.
$47,978
Germain Lexus of Naples
Vehicle information
Ext. color: Ultra White
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
19-26
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L251824A
VIN: 2T2YZMDA2NC317810
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Germain Lexus of Naples review
MARCELLO th Salesman was professional and very well
MARCELLO th Salesman was professional and very well informed about the car Lexus 350h well
2022 Lexus RX 350 F SPORT Handling review
2022 RX 350 Premium…The last of the finest.
I bought my 2022 RX 350 Premium in February, it rides comfortably and the outward visibility is good, overall built in quality and safety features makes you feel at ease and confident on the road ahead, I’m 64 yrs old 6’2 230 lbs and both front ventilated seats are very comfortable. Don’t believe the hype of the Mark Levinson audio system which in itself an excellent addition adds up $$$ to the overall price and unless you have to drive a concert hall all day it is not needed, the built in quality HD system on the Premium suffices for most users, the added CD is a welcoming experience for an old gizzard like me and my classical CD’s. I do not care to start my vehicle using my smartphone, personally the Lexus app is not useful to me, as my choice is to start the vehicle the old fashion way key-fob in my pocket. Thus far I do not use the kick sensor for the power rear door it’s simply enough to touch the bottom on the rear tailgate. I find the touch pad user friendly, no convoluted problems using it on my 8’ inch screen, love the dials quality buttons on the 8 inch screen as well. This RX 350 2022 model is the last of the V6 smooth buttery engines with sufficient power and acceleration yet economical enough, it doesn’t require 91 octane gasoline as it is engineered to perform on 87 octane. Overall I’m very pleased with my 2022 RX 350 and plan to keep it until death keeps us apart. Thank you for reading my heartfelt review.
Used
2022 Lexus RX 350 F SPORT Handling
32,714 mi.
$45,278
$710 price drop
Germain Lexus of Naples
Vehicle information
Ext. color: Caviar
Int. color: Black
Drivetrain: All-wheel Drive
MPG:
19-26
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L251792A
VIN: 2T2YZMDA8NC316502
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Germain Lexus of Naples review
Frank Concepcion and Steve Duran went above and beyond
Frank Concepcion and Steve Duran went above and beyond in meeting our expectations. We felt more like family there than customers. Thank you both for your dedication to providing great customer service.
2022 Lexus RX 350 F SPORT Handling review
Best Vehicle Ever!
I am on my 4th RX350. I love my current 350 but it is 10 years old so I’m looking to replace it. Would not consider another car. It is like new with only 79,500 miles. They are great vehicles.
Used
2022 Lexus RX 350 Base
15,745 mi.
$40,988
$1,010 price drop
Germain Lexus of Naples
Vehicle information
Ext. color: Atomic Silver
Int. color: Black
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L251775A
VIN: 2T2HZMAA6NC256661
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Germain Lexus of Naples review
Excellent customer service experience from my service
Excellent customer service experience from my service advisor (Jackson Kirby)! Germain Lexus is a great dealership from sales to service. Everyone is sooooo nice and attentive.
Used
2022 Lexus RX 350 Base
19,857 mi.
$41,498
Germain Lexus of Naples
Vehicle information
Ext. color: Caviar
Int. color: Black
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: XP12599
VIN: 2T2HZMAA5NC244064
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Germain Lexus of Naples review
Jackson Kirby was professional and caring in helping us
Jackson Kirby was professional and caring in helping us with our car’s service needs! My husband and I always feel we are in good hands with his help.
Used
2022 Lexus RX 350 Base
49,109 mi.
$33,996
$1,361 price drop
Mercedes-Benz of Fort Myers
Vehicle information
Ext. color: Caviar
Int. color: Black
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: TNC251191
VIN: 2T2HZMAA3NC251191
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Satellite Radio, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Mercedes-Benz of Fort Myers review
Excellent sales team!
Excellent sales team!!!!! Best service ever hands down ???? 4th car purchased here!!!! I highly recommend the dealer to anybody looking for an excellent car and a highly reputable brand.
Used
2022 Lexus RX 350 Base
25,619 mi.
$41,589
Jaguar Land Rover of Fort Myers
Vehicle information
Ext. color: Eminent White Pearl
Int. color: Birch
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: NC24584A
VIN: 2T2HZMAA8NC245841
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Reviews
Jaguar Land Rover of Fort Myers review
Thank You Samantha Terepka
This is the 3rd vehicle that I have purchased through by Samantha, She is very knowledgeable about the vehicles that I have purchased… Samantha takes her time with you, she also follows up to make sure everything is OK after the sale. I highly recommend Samantha
There are 15 matching cars close to your year range.
Certified
2023 Lexus RX 350 Luxury
25,457 mi.
$54,478
$410 price drop
Germain Lexus of Naples
Vehicle information
Ext. color: Eminent White Pearl
Int. color: Peppercorn w/Black Open Pore
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: L251682A
VIN: 2T2BAMBA2PC018028
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port
Exterior:
Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2021 Lexus RX 350 Base
23,046 mi.
$39,995
Val Ward Cadillac
Vehicle information
Ext. color: Eminent White Pearl
Int. color: Black
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: Automatic
Engine: Regular Unleaded V-6 3.5 L/211
Stock #: 25494A
VIN: 2T2HZMAA3MC207822
Features
Convenience:
Adaptive Cruise Control, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment:
Bluetooth®, CD Player, HomeLink, Satellite Radio, WiFi Hotspot
Exterior:
Alloy Wheels
Safety:
Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Stability Control
Used
2023 Lexus RX 350 Premium
36,482 mi.
$38,510
$4,562 price drop
Naples Mazda
Vehicle information
Ext. color: Eminent White Pearl
Int. color: Black w/ Black Cascade Trim
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: C001720
VIN: 2T2BAMBA6PC001720
Features
Convenience:
Adaptive Cruise Control, Heated Seats, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, USB Port
Exterior:
Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Vehicle information
Ext. color: Iridium
Int. color: Palomino w/Ash Bamboo
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: PC004642
VIN: 2T2BAMBA5PC004642
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, USB Port
Exterior:
Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2023 Lexus RX 350 Premium Plus
35,124 mi.
$48,232
$400 price drop
DeVoe Cadillac
Vehicle information
Ext. color: Caviar
Int. color: Macadamia w/Ash Bamboo
Drivetrain: All-wheel Drive
MPG:
37-34
Fuel type: Gasoline
Transmission: Automatic
Engine: 2.5L I-4 port/direct injection, DOHC, VVT-iE/VVT-i variable valv
Stock #: C25420A
VIN: 2T2BBMCA9PC017163
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, USB Port
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Certified
2023 Lexus RX 350 Premium Plus
39,645 mi.
$44,295
Lexus of Fort Myers
Vehicle information
Ext. color: Eminent White Pearl
Int. color: Black w/Black Open Pore
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: 8-Speed A/T
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: P2008569
VIN: JTJCHMAA6P2008569
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, USB Port
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2024 Lexus RX 350 Premium Plus
10,431 mi.
$49,787
$3,210 price drop
Fort Myers Genesis
Vehicle information
Ext. color: Matador Red Mica
Int. color: Birch w/Black Open Pore
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: 8-speed automatic
Engine: 2.4L I-4 port/direct injection, DOHC, variable valve control, in
Stock #: FG042850A
VIN: 2T2BAMBA5RC023355
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, USB Port
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Certified
2024 Lexus RX 350 Luxury
37,287 mi.
$60,988
Germain Lexus of Naples
Vehicle information
Ext. color: Eminent White Pearl
Int. color: Black w/Black Open Pore
Drivetrain: All-wheel Drive
MPG:
37-34
Fuel type: Gasoline
Transmission: CVT
Engine: 2.5L I-4 port/direct injection, DOHC, variable valve control, pr
Stock #: L260073A
VIN: 2T2BBMCA2RC023597
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Certified
2023 Lexus RX 350 Luxury
14,687 mi.
$55,998
Germain Lexus of Naples
Vehicle information
Ext. color: Nori Green Pearl
Int. color: Macadamia w/Ash Bamboo
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: L260079A
VIN: 2T2BAMBA9PC021511
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port
Exterior:
Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2021 Lexus RX 350 Base
31,009 mi.
$38,988
Germain Lexus of Naples
Vehicle information
Ext. color: Nori Green Pearl
Int. color: Glazed Caramel
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L251609B
VIN: 2T2HZMAA3MC196112
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2024 Lexus RX 350 Premium Plus
32,533 mi.
$46,995
$500 price drop
Audi Fort Myers
Vehicle information
Ext. color: Matador Red Mica
Int. color: Black w/Black Open Pore
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, variable valve control, in
Stock #: RC03172A
VIN: 2T2BAMBA4RC031723
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, USB Port
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Certified
2023 Lexus RX 350 Luxury
46,240 mi.
$48,978
$3,910 price drop
Germain Lexus of Naples
Vehicle information
Ext. color: Caviar
Int. color: Black w/Black Open Pore
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: L251738A
VIN: 2T2BAMBA9PC012923
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Premium Sound System, USB Port
Exterior:
Alloy Wheels, Roof Rack, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2023 Lexus RX 350 Premium Plus
15,189 mi.
$47,999
BMW of Fort Myers
Vehicle information
Ext. color: Caviar
Int. color: Macadamia w/Ash Bamboo
Drivetrain: Front-wheel Drive
MPG:
22-29
Fuel type: Gasoline
Transmission: Automatic
Engine: 2.4L I-4 port/direct injection, DOHC, Dual VVT-i variable valve
Stock #: TPC018728
VIN: 2T2BAMBA8PC018728
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Folding Mirrors, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, HomeLink, Satellite Radio, USB Port
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2020 Lexus RX 350 Base
34,225 mi.
$36,998
Germain Lexus of Naples
Vehicle information
Ext. color: Atomic Silver
Int. color: Parchment
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: XB12591B
VIN: 2T2HZMAA7LC177741
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
Used
2020 Lexus RX 350 Base
30,677 mi.
$37,998
Germain Lexus of Naples
Vehicle information
Ext. color: Moonbeam Beige Metallic
Int. color: Parchment
Drivetrain: Front-wheel Drive
MPG:
20-27
Fuel type: Gasoline
Transmission: 8-Speed Automatic
Engine: 3.5L V-6 port/direct injection, DOHC, VVT-iW variable valve cont
Stock #: L260054A
VIN: 2T2HZMAA8LC179496
Features
Convenience:
Adaptive Cruise Control, Cooled Seats, Heated Seats, Heated Steering Wheel, Keyless Entry, Keyless Start, Navigation System, Power Liftgate, Remote Start
Entertainment:
Android Auto®, Apple CarPlay®, Bluetooth®, CD Player, HomeLink, Premium Sound System, USB Port, WiFi Hotspot
Exterior:
Alloy Wheels, Sunroof/Moonroof
Safety:
Automatic Emergency Braking, Backup Camera, Blind Spot Monitor, Brake Assist, LED Headlights, Lane Departure Warning, Rain Sensing Wipers, Rear Cross Traffic Alert, Stability Control
Seating:
Leather Seats, Memory Seat
-
Prev - 1
-
Next
Lexus RX 350 prices by year
| Model year | Average price | Deals |
|---|---|---|
| 2026 Lexus RX 350 | $59,724 | |
| 2025 Lexus RX 350 | $57,435 |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $40,764, with pricing starting at $27,799.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
Rating breakdown (out of 5):
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
Rating breakdown (out of 5):
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
| Style | |
|---|---|
| RX 350 FWD | RX 350 AWD |
| Inventory price | |
| Starting at $45,920 | Starting at $47,320 |
| Combined MPG | |
| 23 | 22 |
| Engine | |
| 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
| Style | |
|---|---|
| RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
| Inventory price | |
| Starting at $49,400 | Starting at $50,800 |
| Combined MPG | |
| 23 | 22 |
| Engine | |
| 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
| Style | |
|---|---|
| RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
| Inventory price | |
| Starting at $51,800 | Starting at $53,200 |
| Combined MPG | |
| 23 | 22 |
| Engine | |
| 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2022 Lexus RX 350
Compare the 2022 Lexus RX 350
- ${price_badge()}
- ${ami_badge()}
- ${battery_badge()}${ev_report_link()}
- ${hot_car_badge()}
- ${award_badge()}
- ${cpo_badge()}
${price_badge_description}
${ami_badge_description}
The EV Battery Rating is based on this vehicle's current expected range relative to the vehicles expected range when new. ${battery_badge_text}
This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.