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  • Blue 2022 Lexus RX 350 F SPORT AppearanceBlue 2022 Lexus RX 350 F SPORT AppearanceBlue 2022 Lexus RX 350 F SPORT AppearanceBlue 2022 Lexus RX 350 F SPORT AppearanceBlue 2022 Lexus RX 350 F SPORT AppearanceBlue 2022 Lexus RX 350 F SPORT Appearance

    $34,920

    $200
    71,049 mi.
    Est. $643/mo

    ALM Roswell

    4.4
    Check Availability
    Roswell, GA (19 mi)

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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $29,995

    124,976 mi.
    Est. $552/mo

    Audi Atlanta

    4.9
    Check Availability
    Atlanta, GA (10 mi)
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  • BLACK 2022 Lexus RX 350 BaseBLACK 2022 Lexus RX 350 BaseBLACK 2022 Lexus RX 350 BaseBLACK 2022 Lexus RX 350 BaseBLACK 2022 Lexus RX 350 BaseBLACK 2022 Lexus RX 350 Base

    $36,920

    48,360 mi.
    Est. $680/mo

    Used Imports Auto

    Check Availability
    Lawrenceville, GA (13 mi)
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  • White 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 L

    $46,998

    20,373 mi.
    Est. $865/mo

    CarMax Town Center

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    Kennesaw, GA (26 mi)
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  • Gray 2022 Lexus RX 350 F SPORT HandlingGray 2022 Lexus RX 350 F SPORT HandlingGray 2022 Lexus RX 350 F SPORT HandlingGray 2022 Lexus RX 350 F SPORT HandlingGray 2022 Lexus RX 350 F SPORT HandlingGray 2022 Lexus RX 350 F SPORT Handling

    $41,990

    $3K
    58,922 mi.
    Est. $773/mo

    Town Center Nissan

    4.5
    Check Availability
    Kennesaw, GA (27 mi)
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  • Mica 2022 Lexus RX 350 BaseMica 2022 Lexus RX 350 BaseMica 2022 Lexus RX 350 BaseMica 2022 Lexus RX 350 BaseMica 2022 Lexus RX 350 BaseMica 2022 Lexus RX 350 Base

    $43,790

    $100
    38,052 mi.
    Est. $806/mo

    Hennessy Lexus Gwinnett

    4.2
    Check Availability
    Duluth, GA (13 mi)
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  • Matador Red Mica 2022 Lexus RX 350 PremiumMatador Red Mica 2022 Lexus RX 350 PremiumMatador Red Mica 2022 Lexus RX 350 PremiumMatador Red Mica 2022 Lexus RX 350 PremiumMatador Red Mica 2022 Lexus RX 350 PremiumMatador Red Mica 2022 Lexus RX 350 Premium

    $40,490

    $500
    50,291 mi.
    Est. $746/mo

    Hennessy Lexus of Atlanta

    3.3
    Check Availability
    Atlanta, GA (10 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 Premium

    $42,990

    $500
    31,482 mi.
    Est. $792/mo

    Hennessy Lexus of Atlanta

    3.3
    Check Availability
    Atlanta, GA (10 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $38,290

    $100
    59,609 mi.
    Est. $705/mo

    Hennessy Lexus Gwinnett

    4.2
    Check Availability
    Duluth, GA (13 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $37,259

    $240
    69,224 mi.
    Est. $686/mo

    Nalley Lexus Galleria

    4.8
    Check Availability
    Smyrna, GA (18 mi)
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  • Matador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 Base

    $41,990

    57,955 mi.
    Est. $773/mo

    Hennessy Lexus Gwinnett

    4.2
    Check Availability
    Duluth, GA (13 mi)
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  • Tan 2022 Lexus RX 350 BaseTan 2022 Lexus RX 350 BaseTan 2022 Lexus RX 350 BaseTan 2022 Lexus RX 350 BaseTan 2022 Lexus RX 350 BaseTan 2022 Lexus RX 350 Base

    $43,690

    37,752 mi.
    Est. $804/mo

    Hennessy Lexus Gwinnett

    4.2
    Check Availability
    Duluth, GA (13 mi)
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  • Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350

    $41,998

    30,258 mi.
    Est. $773/mo

    CarMax Norcross

    2.0
    Check Availability
    Norcross, GA (10 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $32,920

    $400
    92,587 mi.
    Est. $606/mo

    ALM Mazda South

    Check Availability
    Morrow, GA (19 mi)
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  • $44,990

    24,015 mi.
    Est. $828/mo

    Hennessy Lexus Gwinnett

    4.2
    Check Availability
    Duluth, GA (13 mi)
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  • Atomic Silver 2022 Lexus RX 350 Base

    $45,900

    15,382 mi.
    Est. $845/mo

    Nalley Lexus Galleria

    4.8
    Check Availability
    Smyrna, GA (18 mi)
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  • $43,894

    27,424 mi.
    Est. $808/mo

    Butler Lexus of South Atlanta

    4.6
    Check Availability
    Union City, GA (25 mi)
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  • Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350

    $33,998

    77,632 mi.
    Est. $626/mo

    CarMax Germantown

    Check Availability
    $199 delivery to Norcross, GA (10 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT Appearance

    $31,699

    96,641 mi.
    Est. $584/mo

    Florida Fine Cars WPB

    4.8
    Check Availability
    $548 delivery from West Palm Beach, FL (548 mi)
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  • 2022 Lexus RX 350 F SPORT Handling2022 Lexus RX 350 F SPORT Handling2022 Lexus RX 350 F SPORT Handling2022 Lexus RX 350 F SPORT Handling2022 Lexus RX 350 F SPORT Handling2022 Lexus RX 350 F SPORT Handling

    $46,995

    32,780 mi.
    Est. $865/mo

    Hardy Superstore

    4.8
    Check Availability
    Dallas, GA (35 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $42,197

    $206
    62,239 mi.
    Est. $777/mo

    Courtesy Ford

    4.5
    Check Availability
    Rome, GA (63 mi)
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  • Black 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 Base

    $27,450

    140,498 mi.
    Est. $505/mo

    Exotic Motors Atlanta

    2.4
    Check Availability
    Gainesville, GA (41 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,389
2025 Lexus RX 350 $54,580 8 Great deals
2024 Lexus RX 350 $51,377 45 Good deals
2023 Lexus RX 350 $48,114 32 Good deals
2021 Lexus RX 350 $34,648 7 Good deals
2019 Lexus RX 350 $29,264 10 Good deals
2017 Lexus RX 350 $25,515 9 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $39,641, with pricing starting at $5,501.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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