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  • Grecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT Appearance

    $42,990

    22,302 mi.
    Est. $781/mo

    Bomnin Chevrolet Buick GMC Nanuet

    4.7
    Check Availability
    Nanuet, NY (21 mi)

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  • Grecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT Appearance

    $42,990

    22,302 mi.
    Est. $781/mo

    Bomnin Chevrolet Buick GMC Nanuet

    4.7
    Check Availability
    Nanuet, NY (21 mi)

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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $41,998

    19,563 mi.
    Est. $763/mo

    New Country Lexus of Great Neck

    4.5
    Check Availability
    Great Neck, NY (26 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $35,998

    55,742 mi.
    Est. $654/mo

    New Country Lexus of Great Neck

    4.5
    Check Availability
    Great Neck, NY (26 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $41,800

    29,267 mi.
    Est. $760/mo

    MajorWorld Chevy

    4.0
    Check Availability
    Long Island City, NY (17 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $39,877

    38,322 mi.
    Est. $725/mo

    Salerno Duane Chrysler Jeep Dodge Ram

    4.5
    Check Availability
    Summit, NJ (12 mi)
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  • Black 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 Base

    $38,997

    27,410 mi.
    Est. $709/mo

    Tri-County Lexus

    4.7
    Check Availability
    Little Falls, NJ (3 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $36,842

    $476
    76,205 mi.
    Est. $670/mo

    Stream Auto Outlet Valley Stream

    4.3
    Check Availability
    Valley Stream, NY (29 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT Appearance

    $36,991

    43,435 mi.
    Est. $672/mo

    Edison Nissan

    3.9
    Check Availability
    Edison, NJ (26 mi)
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  • Nightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT Appearance

    $41,353

    $642
    26,740 mi.
    Est. $752/mo

    Tri-County Lexus

    4.7
    Check Availability
    Little Falls, NJ (3 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT Appearance

    $35,990

    33,683 mi.
    Est. $654/mo

    Auto Lux

    3.4
    Check Availability
    Elmont, NY (29 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $33,990

    74,362 mi.
    Est. $618/mo

    Auto Lux

    3.4
    Check Availability
    Elmont, NY (29 mi)
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  • White 2022 Lexus RX 350 F SPORT AppearanceWhite 2022 Lexus RX 350 F SPORT AppearanceWhite 2022 Lexus RX 350 F SPORT AppearanceWhite 2022 Lexus RX 350 F SPORT AppearanceWhite 2022 Lexus RX 350 F SPORT AppearanceWhite 2022 Lexus RX 350 F SPORT Appearance

    $37,293

    $199
    49,712 mi.
    Est. $678/mo

    Carz4Us Pine Brook

    3.5
    Check Availability
    Pine Brook, NJ (8 mi)
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  • Red 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 Base

    $30,600

    38,564 mi.
    Est. $556/mo

    G-Motors of Old Bridge

    4.4
    Check Availability
    Old Bridge, NJ (29 mi)
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  • Caviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWDCaviar 2022 Lexus RX 350 RX 350 AWD

    $27,995

    79,356 mi.
    Est. $509/mo

    Victory Mitsubishi

    3.4
    Check Availability
    Bronx, NY (20 mi)
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  • Silver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 Base

    $27,995

    78,148 mi.
    Est. $509/mo

    Power Motors NYC Inc

    3.6
    Check Availability
    Bellerose, NY (27 mi)
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  • Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350

    $46,998

    15,292 mi.
    Est. $854/mo

    CarMax Greenwood

    Check Availability
    $649 delivery to Wayne, NJ (8 mi)
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  • Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350

    $39,998

    $2K
    49,409 mi.
    Est. $727/mo

    CarMax White Marsh

    Check Availability
    $99 delivery to Wayne, NJ (8 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $38,995

    55,163 mi.
    Est. $709/mo

    Auto Hub

    4.6
    Check Availability
    North Brunswick, NJ (34 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $43,400

    31,073 mi.
    Est. $789/mo

    Stoler Lexus

    4.7
    Check Availability
    Farmingdale, NY (42 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $44,943

    19,146 mi.
    Est. $817/mo

    BMW of Freeport

    4.9
    Check Availability
    Freeport, NY (35 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $37,695

    $200
    56,417 mi.
    Est. $685/mo

    Malouf Ford Lincoln

    4.7
    Check Availability
    North Brunswick, NJ (32 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $40,000

    31,054 mi.
    Est. $727/mo

    Porsche Greenwich

    4.7
    Check Availability
    Greenwich, CT (33 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $40,178

    36,438 mi.
    Est. $730/mo

    Autolenders Lawrenceville

    4.9
    Check Availability
    Lawrence, NJ (49 mi)
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  • $41,500

    38,962 mi.
    Est. $754/mo

    Lexus of Freeport

    4.7
    Check Availability
    Rockville Centre, NY (32 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $64,591
2025 Lexus RX 350 $50,343 7 Good deals
2024 Lexus RX 350 $48,284 20 Good deals
2023 Lexus RX 350 $44,564 29 Good deals
2021 Lexus RX 350 $36,122 4 Good deals
2020 Lexus RX 350 $30,374 9 Good deals
2017 Lexus RX 350 $22,822 16 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,520, with pricing starting at $27,450.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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