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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $41,899

    32,368 mi.
    Est. $757/mo

    DARCARS Lexus Of Silver Spring

    4.7
    Check Availability
    Silver Spring, MD (13 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $32,995

    $1K
    55,335 mi.
    Est. $596/mo

    Auto Buying Service

    2.8
    Check Availability
    Fairfax, VA (19 mi)
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  • Red 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 Base

    $41,880

    34,822 mi.
    Est. $757/mo

    Passport Mazda

    Check Availability
    Camp Springs, MD (5 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $29,082

    123,846 mi.
    Est. $526/mo

    DARCARS Lexus Of Silver Spring

    4.7
    Check Availability
    Silver Spring, MD (13 mi)
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  • $45,000

    19,740 mi.
    Est. $813/mo

    Ourisman Lexus

    4.8
    Check Availability
    Rockville, MD (22 mi)
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  • Not Priced

    48,498 mi.
    Est. $0/mo

    DARCARS Chrysler Dodge Jeep Ram of New Carrollton

    4.3
    Check Availability
    New Carrollton, MD (6 mi)
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  • Not Priced

    25,562 mi.
    Est. $0/mo

    DARCARS Lexus Of Silver Spring

    4.7
    Check Availability
    Silver Spring, MD (13 mi)
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  • Not Priced

    42,813 mi.
    Est. $0/mo

    DARCARS Lexus Of Silver Spring

    4.7
    Check Availability
    Silver Spring, MD (13 mi)
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  • Caviar 2022 Lexus RX 350 Base

    $49,577

    $323
    11,736 mi.
    Est. $896/mo

    Pohanka Lexus

    3.8
    Check Availability
    Chantilly, VA (30 mi)
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  • Caviar 2022 Lexus RX 350 Base

    $42,700

    $200
    46,987 mi.
    Est. $772/mo

    Pohanka Lexus

    3.8
    Check Availability
    Chantilly, VA (30 mi)
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  • White 2022 Lexus RX 350White 2022 Lexus RX 350White 2022 Lexus RX 350White 2022 Lexus RX 350White 2022 Lexus RX 350White 2022 Lexus RX 350

    $37,998

    52,008 mi.
    Est. $687/mo

    CarMax East Meadow

    Check Availability
    $99 delivery to Brandywine, MD (15 mi)
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  • Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350

    $39,998

    36,700 mi.
    Est. $723/mo

    CarMax Jackson (TN)

    Check Availability
    $599 delivery to Brandywine, MD (15 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $38,958

    46,634 mi.
    Est. $704/mo

    AutoNation Toyota Leesburg

    4.8
    Check Availability
    Leesburg, VA (38 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $37,322

    $668
    50,098 mi.
    Est. $674/mo

    AutoNation Toyota Leesburg

    4.8
    Check Availability
    Leesburg, VA (38 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $30,999

    17,673 mi.
    Est. $560/mo

    Premier Automotive

    1.5
    Check Availability
    Dumfries, VA (32 mi)
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  • Red 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 Base

    $32,495

    78,277 mi.
    Est. $587/mo

    Kargar Motors of Manassas

    1.9
    Check Availability
    Manassas, VA (32 mi)
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  • Blue 2022 Lexus RX 350 Base

    $41,000

    59,657 mi.
    Est. $741/mo

    Len Stoler Lexus

    4.5
    Check Availability
    Owings Mills, MD (39 mi)
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  • Not Priced

    49,588 mi.
    Est. $0/mo

    Lexus of Towson

    4.8
    Check Availability
    Towson, MD (40 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $62,992 1 Good deal
2025 Lexus RX 350 $52,612 11 Great deals
2024 Lexus RX 350 $48,761 34 Good deals
2023 Lexus RX 350 $47,414 18 Good deals
2017 Lexus RX 350 $27,308 6 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $40,044, with pricing starting at $27,450.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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