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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class
for sale
near
Anaheim, CA
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
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Reviews
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
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Reviews
Mercedes of ontario the best place to purchase !!
On November 25th I went to the Mercedes on Ontario, and was looking to buy an electric car around 7pm in the evening, I was looking at the EQB 350 when this very nice sales representative Abel Vargas helped us and was very nice and interactive explained to us what was good about the electric vehicles, at the end of the point of buying the EQB 350 the transaction at around 2am Black Friday after hours but I will like to mention excellent and outstanding sales person human being his name is fadi batarni I had a situation where I had to call him, a couple days after but was out of town but still answered right away, like always nice friendly and helpful manner, and I really appreciate the help and appreciate the huge help on purchasing my EQB 350 Thank you much guys I really like my car.
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
Features
Reviews
great service.
great service. Jose is the man! i cant wait to hit the road and drive this beautiful car. thank you everyone. wonderful experience.what else do i need to say
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
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Reviews
I never write reviews….
I never write reviews…. BUT!!! A HUGE thanks to salesman JEFF! We appreciated his professionalism and passion to help us find our new car. Even after buying ours, he was so kind and quick to answer any of our questions. We are definitely recommending Jeff to our friends and families!
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.






Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
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recently visited Mercedes-Benz and had the pleasure of
recently visited Mercedes-Benz and had the pleasure of working with Mr. Jeff Tarin regarding the end of my lease end. I came in with a few preferences, which was to leaver MB & purchase a car with another Brand. I was uncertain about the most financially responsible path—whether to end my lease, purchase my current vehicle, or explore a new one. Jeff was incredibly mindful, honest, resourceful, and supportive throughout the entire process. His charismatic and empathetic approach immediately put me at ease. He took the time to thoroughly educate me on all available options, including the financial implications of each, while paying close attention to both my needs and my financial comfort. Although I ultimately decided to purchase a new vehicle, Jeff ensured that I felt confident, informed, and genuinely happy with my decision. His professionalism and care made a lasting impression, and I’m truly grateful for the time and attention he dedicated to assisting me. Thanks to Jeff’s exceptional service, I remain a proud and loyal Mercedes-Benz customer since 2017, and I look forward to returning to him for all future needs—both for myself and for my family and friends.
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.






Used
2021 Mercedes-Benz E-Class E 350
Vehicle information
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Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 350
Vehicle information
Reviews
Yearly maintenance
I took my car in for yearly maintenance service on September 10, 2020. My service advisor was Tino and he was great. Everyone at Mercedes-Benz Los Angeles were very friendly and courteous.
There are 20 matching cars close to your year range.






Mercedes-Benz Certified
2022 Mercedes-Benz E-Class E 350
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2022 Mercedes-Benz E-Class E 350
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2022 Mercedes-Benz E-Class E 350
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2022 Mercedes-Benz E-Class 4MATIC
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Mercedes-Benz Certified
2022 Mercedes-Benz E-Class E 350
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Mercedes-Benz E-Class prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Mercedes-Benz E-Class | $59,613 | 3 Good deals |
2023 Mercedes-Benz E-Class | $40,933 | 3 Good deals |
2022 Mercedes-Benz E-Class | $30,449 | 15 Good deals |
2020 Mercedes-Benz E-Class | $27,892 | 4 Good deals |
2018 Mercedes-Benz E-Class | $18,999 | 6 Good deals |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)

How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $36,399, with pricing starting at $23,000.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class compares to and/or competes against the following vehicles:
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
Style | |
---|---|
E 350 RWD Sedan | E 350 4MATIC Sedan |
Inventory price | |
Starting at $54,250 | Starting at $56,750 |
Combined MPG | |
25 | 25 |
Engine | |
255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
Style | |||||
---|---|---|---|---|---|
E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
Inventory price | |||||
Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
Combined MPG | |||||
25 | 24 | 25 | 26 | 26 | 25 |
Engine | |||||
362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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