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*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
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Used
2021 Mercedes-Benz E-Class wagons
for sale
near me
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Used
2021 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Features
Reviews
The 2026 Audi A6 Prestige is the 14th Audi I’ve owned
The 2026 Audi A6 Prestige is the 14th Audi I’ve owned since 1984. I lived in Washington DC for many years and I have dealt with several Audi dealerships in DC, Maryland and Virginia during that time. Besides being a great car I have always experienced the best service, the most helpful and professional staff and a seamless process from my first of many questions, the final set of paper work to finally pulling out of the dealership. My experience at Lenox Audi has surpassed them all. Their new headquarters on Rt 7 in Lenox is magnificent but, of course, the staff, the staff! Travis from Service and Matt McDonough from Sales represent the best of what Audi is all about. Delightful, solicitous, and prepared to take as much time to “answer and explain” . And believe me, even after the many years driving an Audi, with all the new technology, I need a lot of instruction so that my Audi can continue, after all these years, to provide the best driving experience possible. And I get that and more at Lenox Audi. Jack Myslinski
Most beautiful car I have ever had
I love my car All the technology on it it’s like a dream Interiores are so beautifully design and comfortable Runs so smooth, I feel like a millionaire driving it🥰
Used
2021 Mercedes-Benz E-Class E 450 4MATIC All-Terrain
Vehicle information
Features
Reviews
Jack Cotton was a delight to work with and the only
Jack Cotton was a delight to work with and the only reason I didn’t purchase a Bentley from him is because I decided to purchase a car closer to my home!
Very nice car so far
Owned for a month so far. Aside from a slight rattle occasionally in the passenger door everything is great. Still on the 1000 mile engine break-in but it is very quick. Gas mileage is running about 20 MPG in town and 29 on the highway. Very comfortable and feels very much like a luxury car. Traded in a 2016 Audi A6 which was also a very good car. The E450 just feels more luxurious and quicker. Slightly better steering feel as well.
Used
2021 Mercedes-Benz E-Class E 450
Vehicle information
Features
Reviews
I would recommend to my friends
I have good experience with this dealership. Pro and cons: Pro: excellent customer service. Thank you Valerie Naval. She helped me and explained everything I asked her. Cons: Car needs to be prep for sale, deep cleaning or at least check it out for anything leftover from previous owner. But Valerie offer me reimbursement for detailing my car. Most of all if you don't like your car for any reason return policy excellent with out any hidden fees, check with your salesperson for details. I would recommend Carmax to my friends .
One of the best cars I’ve ever owned
The car rides great and looks good. I like the lines and response of the car. Nice color and the features are excellent. I recommend this dealership and car to everyone.
Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Reviews
Great place, Joe falconer has always been overly helpful.
Great place, Joe falconer has always been overly helpful. I buy parts for the shop with these guys and wouldn't recommend any other Mercedes Benz dealer.
This car is why you buy a Mercedes-Benz.
I'm replacing a 17 y/o E-320 that I loved. I am now infatuated with the New 2021 E-450 4 matic it just so happens to be the Motor Trend car of the year. Very nice exterior styling. Fantastic interior. all the latest technology and a great interior. The strait V-6 with turbo is smooth as silk. The optional Air Body control suspension makes for a fantastic smooth ride.
Mercedes-Benz Certified
2021 Mercedes-Benz E-Class E 450 4MATIC
Vehicle information
Features
Reviews
Just bought a nice used Maxima here this weekend.
Just bought a nice used Maxima here this weekend. I will have to say that Brandon Comer (sales) and Javier Escobar (finance) were a pleasure to deal with. Such down to earth personalities, friendly, sincere, and helpful. I actually identified a vibration / wheel issue with this vehicle during the test drive. They did not hesitate to address the issue fully and we were able to finalize the deal in a couple of days. Other that that small hiccup, the dealwas so simple and painless. My wife and I would definitely consider buying from this dealership again. It is a beautiful establishment and everyone we came in contact with were so nice and thoughtful.
Love my Car
The vehicle meets all of my needs. I special ordered the vehicle with the color and leather interior I prefer. It arrived exactly the way I wanted.
Mercedes-Benz Certified
2021 Mercedes-Benz E-Class
Vehicle information
Reviews
Katelyn, Ethan and my salesman were PHENOMENAL.
Katelyn, Ethan and my salesman were PHENOMENAL. Professional, thorough and fast. Mercedes type of service was on point at point of sale.
Used
2021 Mercedes-Benz E-Class E 450 4MATIC All-Terrain
Vehicle information
Features
Reviews
This was the best car buying experience I have had.
This was the best car buying experience I have had. I have bought 3 used cars within this last year and I also bought one in 2022. I ended up at Auto Trademark because my 22-year-old Honda Accord was kaput. Auto trademark was a relaxed environment from the start. We test drove the 2013 BMW 535i drive with the sports package. We liked it but the A/C on passenger vent didn’t seem cool enough. Z offered to get that checked out and fixed. They also said we could but use a check from my HELOC, no high-pressure sales job for warranties or financing (which adds hours to the transaction and makes you feel exhausted). When I picked up the car after they fixed the A/C, I asked why this particular car had no floor mats (which they noted right away at the test drive), Farhan said they had wondered that too, and immediately offered to order replacement mats. I was thrilled. It was such a good experience and the price was reasonable. I’ll note that I didn’t negotiate, and the posted price on CarGurus was the $1,000 less than what I was charged because they note in the ad that it is listed assuming a military discount. But I had read that in the ad, so it was OK for me. I would recommend this auto dealership to anyone who is in the market for a nice used car and wants a positive buying experience.
Used
2021 Mercedes-Benz E-Class E 450 4MATIC All-Terrain
Vehicle information
Features
Reviews
After searching for over two weeks, I finally purchased a
After searching for over two weeks, I finally purchased a 2023 Toyota Camry as my first car—and C&K made the process smoother than I ever could have imagined! The team was knowledgeable, transparent, and answered all of my questions without any pressure. Best of all, there were no outrageous or hidden fees. I couldn’t be happier with my experience and would absolutely recommend C&K to anyone looking for a car!
Used
2021 Mercedes-Benz E-Class E 63 AMG 4MATIC
Vehicle information
Features
Reviews
Quick efficient
Vaani is amazing and has spoiled it for other dealerships! He had vehicle options for me and sent them to me to review prior to arrival. When I arrived the cars were available for me to look at and he accompanied me on the test drive pointing out major & minor features! I already had a Mercedes but was considering buying a non Mercedes (crazy huh) but the dealership I went to was not welcoming and more like I was an inconvenience. Very appreciative of the quick efficient process and I Love my new car💕
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Mercedes-Benz E-Class prices by year
| Model year | Average price | Deals |
|---|---|---|
| 2026 Mercedes-Benz E-Class | $92,639 | |
| 2025 Mercedes-Benz E-Class | $78,618 | 11 Great deals |
| 2023 Mercedes-Benz E-Class | $59,619 | 4 Good deals |
About the 2021 Mercedes-Benz E-Class
E 350 shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Rear-wheel drive
- Combined MPG
- 25
- Transmission
- 9-Speed A/T
- Engine
- 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel)
How much does the 2021 Mercedes-Benz E-Class cost?
The 2021 Mercedes-Benz E-Class price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 E-Class is $33,749, with pricing starting at $19,995.
What is the MPG of the 2021 Mercedes-Benz E-Class?
The 2021 Mercedes-Benz E-Class offers up to 22 MPG in city driving and 31 MPG on the highway for a combined rating of 25 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
Is the 2021 Mercedes-Benz E-Class reliable?
The 2021 Mercedes-Benz E-Class has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 E-Class owners.
Is the 2021 Mercedes-Benz E-Class a good sedan?
Below are the Cars.com consumer ratings for the 2021 Mercedes-Benz E-Class.
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.4
- Performance 4.3
- Value 4.0
- Exterior 4.4
- Reliability 3.9
E 350 (2 styles)
| Style | |
|---|---|
| E 350 RWD Sedan | E 350 4MATIC Sedan |
| Inventory price | |
| Starting at $54,250 | Starting at $56,750 |
| Combined MPG | |
| 25 | 25 |
| Engine | |
| 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) | 255.0-hp, 2.0-liter, 4 Cylinder Engine (Gasoline Fuel) |
E 450 (6 styles)
| Style | |||||
|---|---|---|---|---|---|
| E 450 4MATIC Cabriolet | E 450 4MATIC All-Terrain Wagon | E 450 4MATIC Coupe | E 450 RWD Coupe | E 450 4MATIC Sedan | E 450 RWD Cabriolet |
| Inventory price | |||||
| Starting at $74,450 | Starting at $67,600 | Starting at $67,450 | Starting at $64,950 | Starting at $62,000 | Starting at $71,950 |
| Combined MPG | |||||
| 25 | 24 | 25 | 26 | 26 | 25 |
| Engine | |||||
| 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) | 362.0-hp, 3.0-liter, Straight 6 Cylinder Engine (Gasoline/Mild Electric Hybrid) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
Research the 2021 Mercedes-Benz E-Class
Compare the 2021 Mercedes-Benz E-Class
Mercedes-Benz E-Class trims
-
Mercedes-Benz E-Class 2021 E 350
1 Great Deal out of 86 listings starting at $22,795
-
Mercedes-Benz E-Class 2021 E 350 4MATIC
2 Great Deals out of 60 listings starting at $19,995
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Mercedes-Benz E-Class 2021 E 450 4MATIC
31 listings starting at $21,495
-
Mercedes-Benz E-Class 2021 E 450
1 Great Deal out of 20 listings starting at $29,495
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.
