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Used
2022 Lexus RX 350
for sale
near me
- Down Payment
- $0
- Net trade-in value
- $0
- Months
- 72
- APR
- 7.0%
- Sales tax
- 0.0%
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Love this car.
Love this car. Sitting in the driver’s seat is so comfortable. Silky smooth engine. Rides so nice and quiet. We have looked for this color Grecian water for a long time. Wanted no newer than a 2022 because we didn’t want the 4 cylinder. The 3.5 V6 runs so smooth. Would definitely recommend the purchase of this SUV.






Used
2022 Lexus RX 350 F SPORT Handling
Vehicle information
Features
Reviews
Todd Smith is my new service advisor and he was great he
Todd Smith is my new service advisor and he was great he answered all our questions and concerns and had a great positive welcoming attitude!
Great Car
This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own
Used
2022 Lexus RX 350 Base
Vehicle information
Features
Reviews
Working with Jason Smith was Awesome.
Working with Jason Smith was Awesome. Helpful and not pushy. Our 4th car from Lexus Easton, no sense going any where else
Great vehicle!
It might be early for my review, since we have only owned the car a month; however, the Lexus has so far lived up to its reputation. I'm still getting used to all the electronics, but there are a number of safety features that enhance the driving experience.
There are 20 matching cars close to your year range.






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2024 Lexus RX 350 F SPORT Handling
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2024 Lexus RX 350 F SPORT Handling
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Certified
2024 Lexus RX 350 F SPORT Handling
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Certified
2023 Lexus RX 350 Base
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2024 Lexus RX 350 F SPORT Handling
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2023 Lexus RX 350 Premium Plus
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2024 Lexus RX 350 Luxury
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Lexus RX 350 prices by year
Model year | Prices from | Deals |
---|---|---|
2025 Lexus RX 350 | $46,977 | 103 Great deals |
2024 Lexus RX 350 | $41,388 | 68 Great deals |
2023 Lexus RX 350 | $38,654 | 9 Great deals |
2021 Lexus RX 350 | $25,995 | 15 Great deals |
2020 Lexus RX 350 | $22,994 | 5 Great deals |
2019 Lexus RX 350 | $19,998 | 36 Great deals |
2018 Lexus RX 350 | $19,911 | 13 Great deals |
2017 Lexus RX 350 | $15,985 | 35 Great deals |
2016 Lexus RX 350 | $15,400 | 5 Great deals |
About the 2022 Lexus RX 350
Base shown (base trim).
- Seating
- 5
- Door count
- 4
- Drivetrain
- Front-wheel drive
- Combined MPG
- 23
- Transmission
- 8-Speed A/T
- Engine
- 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

How much does the 2022 Lexus RX 350 cost?
The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,108, with pricing starting at $28,592.
What is the MPG of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.
These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.
What are some similar vehicles and competitors of the 2022 Lexus RX 350?
The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:
Is the 2022 Lexus RX 350 reliable?
The 2022 Lexus RX 350 has an average reliability rating of 4 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.
Is the 2022 Lexus RX 350 a good SUV?
Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
66% of drivers recommend this car
- Comfort 4.6
- Interior 4.5
- Performance 3.8
- Value 3.6
- Exterior 4.7
- Reliability 4.0
RX 350 (2 styles)
Style | |
---|---|
RX 350 FWD | RX 350 AWD |
Inventory price | |
Starting at $45,920 | Starting at $47,320 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Appearance (2 styles)
Style | |
---|---|
RX 350 F SPORT Appearance FWD | RX 350 F SPORT Appearance AWD |
Inventory price | |
Starting at $49,400 | Starting at $50,800 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
RX 350 F SPORT Handling (2 styles)
Style | |
---|---|
RX 350 F SPORT Handling FWD | RX 350 F SPORT Handling AWD |
Inventory price | |
Starting at $51,800 | Starting at $53,200 |
Combined MPG | |
23 | 22 |
Engine | |
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) | 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) |
*Estimated payments are calculated by Cars.com and are for informational purposes only. We’ve estimated your taxes based on your provided ZIP code. These estimates do not include title, registration fees, lien fees, or any other fees that may be imposed by a governmental agency in connection with the sale and financing of the vehicle. Other taxes may apply. They do not represent a financing offer or a guarantee of credit from the seller. Actual terms vary by lender.
**Your Saved Vehicles list will be shared along with your contact information when you submit a vehicle request to a dealership. To opt out of this sharing, please view your options on Cars.com Privacy Notice.
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Research the 2022 Lexus RX 350
Compare the 2022 Lexus RX 350
2022 Lexus RX 350 by popular city
-
2022 Lexus RX 350 in Atlanta, GA
20 listings starting at $34,990
-
2022 Lexus RX 350 in Chicago, IL
1 Great Deal out of 19 listings starting at $35,990
-
2022 Lexus RX 350 in Dallas, TX
35 listings starting at $34,997
-
2022 Lexus RX 350 in Houston, TX
1 Great Deal out of 31 listings starting at $32,495
-
2022 Lexus RX 350 in Los Angeles, CA
18 listings starting at $30,440
-
2022 Lexus RX 350 in New York, NY
4 Great Deals out of 59 listings starting at $29,900
-
2022 Lexus RX 350 in Philadelphia, PA
1 Great Deal out of 16 listings starting at $36,990
-
2022 Lexus RX 350 in Phoenix, AZ
11 listings starting at $31,900
Lexus RX 350 trims
-
Lexus RX 350 2022 Base
14 Great Deals out of 575 listings starting at $28,592
-
Lexus RX 350 2022 F SPORT Handling
2 Great Deals out of 117 listings starting at $34,911
-
Lexus RX 350 2022 F SPORT Appearance
4 Great Deals out of 81 listings starting at $33,692
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This vehicle is certified pre-owned, backed by a manufacturer warranty, and typically undergoes a rigorous multi-point inspection to ensure quality and reliability.
This vehicle is currently in high demand given its competitive price, desirable features, and overall condition, and may have a higher chance of selling quickly.