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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $36,865

    $569
    52,211 mi.
    Est. $680/mo

    Van Hyundai

    4.2
    Check Availability
    Carrollton, TX (29 mi)
    Quick view
  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $49,900

    5,689 mi.
    Est. $921/mo

    Park Place Lexus Plano

    4.8
    Check Availability
    Plano, TX (22 mi)
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  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $43,900

    36,471 mi.
    Est. $810/mo

    Park Place Lexus Plano

    4.8
    Check Availability
    Plano, TX (22 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $32,416

    $500
    86,868 mi.
    Est. $598/mo

    Toyota of Plano

    4.7
    Check Availability
    Plano, TX (21 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $39,290

    48,257 mi.
    Est. $725/mo

    Shottenkirk Chrysler Dodge Jeep Ram Prosper

    4.4
    Check Availability
    Prosper, TX (12 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $33,999

    44,893 mi.
    Est. $627/mo

    Fair Kar, Inc

    Check Availability
    Plano, TX (27 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $30,995

    112,026 mi.
    Est. $572/mo

    European Motors

    3.2
    Check Availability
    Plano, TX (25 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $40,985

    $9K
    28,840 mi.
    Est. $756/mo

    Crest INFINITI

    4.8
    Check Availability
    Frisco, TX (21 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT Handling

    $45,990

    35,101 mi.
    Est. $849/mo

    Group 1 Chrysler Dodge Jeep RAM Denton

    4.6
    Check Availability
    Denton, TX (18 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    Not Priced

    26,591 mi.
    Est. $0/mo

    Park Place Lexus Plano

    4.8
    Check Availability
    Plano, TX (22 mi)
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  • Black 2022 Lexus RX 350 F-SportBlack 2022 Lexus RX 350 F-SportBlack 2022 Lexus RX 350 F-SportBlack 2022 Lexus RX 350 F-SportBlack 2022 Lexus RX 350 F-SportBlack 2022 Lexus RX 350 F-Sport

    $42,998

    49,494 mi.
    Est. $794/mo

    CarMax Omaha

    4.6
    Check Availability
    $349 delivery to Denton, TX (17 mi)
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  • Red 2022 Lexus RX 350Red 2022 Lexus RX 350Red 2022 Lexus RX 350Red 2022 Lexus RX 350Red 2022 Lexus RX 350Red 2022 Lexus RX 350

    $34,998

    55,048 mi.
    Est. $646/mo

    CarMax Killeen

    4.8
    Check Availability
    Free delivery to Denton, TX (17 mi)
    Quick view
  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $42,988

    36,098 mi.
    Est. $793/mo

    Sewell BMW of Grapevine

    3.8
    Check Availability
    Grapevine, TX (33 mi)
    Quick view
  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $36,550

    $200
    79,189 mi.
    Est. $675/mo

    Rockwall Kia

    4.2
    Check Availability
    Rockwall, TX (43 mi)
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  • Black 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 Base

    $43,617

    23,220 mi.
    Est. $805/mo

    DallasLeaseReturns.com

    5.0
    Check Availability
    Dallas, TX (30 mi)
    Quick view
  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $37,690

    $200
    85,170 mi.
    Est. $696/mo

    Principle Volkswagen Grapevine

    4.7
    Check Availability
    Grapevine, TX (38 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $43,984

    $1K
    18,335 mi.
    Est. $812/mo

    Toyota of Richardson

    4.7
    Check Availability
    Richardson, TX (31 mi)
    Quick view
  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $47,880

    39,227 mi.
    Est. $884/mo

    Autos of Dallas Irving

    3.5
    Check Availability
    Irving, TX (37 mi)
    Quick view
  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $46,998

    32,837 mi.
    Est. $867/mo

    Sewell Lexus of Dallas

    3.7
    Check Availability
    Dallas, TX (38 mi)
    Quick view
  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $36,975

    71,603 mi.
    Est. $682/mo

    Park Place Lexus Grapevine

    4.7
    Check Availability
    Grapevine, TX (33 mi)
    Quick view
  • Nori Green Pearl 2022 Lexus RX 350 BaseNori Green Pearl 2022 Lexus RX 350 Base

    $41,975

    48,904 mi.
    Est. $775/mo

    Park Place Lexus Grapevine

    4.7
    Check Availability
    Grapevine, TX (33 mi)
    Quick view
  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $29,999

    38,551 mi.
    Est. $554/mo

    Strategic Auto Group

    3.4
    Check Availability
    Garland, TX (38 mi)
    Quick view
  • $43,435

    31,782 mi.
    Est. $802/mo

    Sport City Toyota

    3.8
    Check Availability
    Dallas, TX (39 mi)
    Quick view

Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $64,388 1 Good deal
2024 Lexus RX 350 $52,459 9 Good deals
2023 Lexus RX 350 $46,986 15 Good deals
2016 Lexus RX 350 $22,179 6 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $39,981, with pricing starting at $27,450.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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