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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $36,492

    66,676 mi.
    Est. $673/mo

    eCarOne

    4.8
    Plano, TX (30 mi)
    Check Availability

  • Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350

    $41,998

    30,512 mi.
    Est. $775/mo

    CarMax Garland

    4.6
    Garland, TX (24 mi)
    Check Availability
  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $40,215

    27,941 mi.
    Est. $742/mo

    Palomino Motors

    Dallas, TX (24 mi)
    Check Availability
  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $36,492

    66,676 mi.
    Est. $673/mo

    eCarOne

    4.8
    Plano, TX (30 mi)
    Check Availability
  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $29,959

    83,532 mi.
    Est. $553/mo

    Strategic Auto Group

    Garland, TX (24 mi)
    Check Availability
  • Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350

    $44,998

    $1K
    22,060 mi.
    Est. $830/mo

    CarMax Texas Stadium (Irving)

    4.4
    Irving, TX (22 mi)
    Check Availability
  • Black 2022 Lexus RX 350 F SPORT HandlingBlack 2022 Lexus RX 350 F SPORT HandlingBlack 2022 Lexus RX 350 F SPORT HandlingBlack 2022 Lexus RX 350 F SPORT HandlingBlack 2022 Lexus RX 350 F SPORT HandlingBlack 2022 Lexus RX 350 F SPORT Handling

    $40,883

    57,379 mi.
    Est. $755/mo

    Auto Locators of Texas

    3.6
    Plano, TX (12 mi)
    Check Availability
  • Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350

    $37,998

    $1K
    62,794 mi.
    Est. $701/mo

    CarMax Texas Stadium (Irving)

    4.4
    Irving, TX (22 mi)
    Check Availability
  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $31,213

    $999
    87,358 mi.
    Est. $576/mo

    Autos of Dallas

    3.7
    Plano, TX (12 mi)
    Check Availability
  • Ultra White 2022 Lexus RX 350 BaseUltra White 2022 Lexus RX 350 BaseUltra White 2022 Lexus RX 350 BaseUltra White 2022 Lexus RX 350 BaseUltra White 2022 Lexus RX 350 BaseUltra White 2022 Lexus RX 350 Base

    $40,275

    $900
    30,387 mi.
    Est. $743/mo

    Grubbs Acura

    3.4
    Grapevine, TX (19 mi)
    Check Availability
  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $47,213

    18,640 mi.
    Est. $871/mo

    Sewell Lexus of Dallas

    3.2
    Dallas, TX (22 mi)
    Check Availability
  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $47,223

    55,312 mi.
    Est. $872/mo

    Sewell Lexus of Dallas

    3.2
    Dallas, TX (22 mi)
    Check Availability
  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $40,221

    $4K
    41,628 mi.
    Est. $742/mo

    Texas Car One

    3.4
    Carrollton, TX (14 mi)
    Check Availability
  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $31,581

    116,039 mi.
    Est. $583/mo

    Excellence Auto Direct

    2.8
    Euless, TX (25 mi)
    Check Availability
  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $36,998

    $971
    74,446 mi.
    Est. $683/mo

    Hi Line Motors

    2.7
    Plano, TX (12 mi)
    Check Availability
  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $36,213

    84,509 mi.
    Est. $668/mo

    Sewell Lexus of Dallas

    3.2
    Dallas, TX (22 mi)
    Check Availability
  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $43,680

    57,196 mi.
    Est. $806/mo

    Tom Clark Chevrolet

    Denton, TX (17 mi)
    Check Availability
  • $43,215

    33,893 mi.
    Est. $798/mo

    Sewell BMW MINI of Plano

    3.8
    Plano, TX (7 mi)
    Check Availability
  • Matador Red Mica 2022 Lexus RX 350 F SPORT Handling

    $47,555

    17,046 mi.
    Est. $878/mo

    Richardson Chrysler Jeep Dodge Ram

    4.6
    Richardson, TX (16 mi)
    Check Availability
  • Not Priced

    27,402 mi.
    Est. $0/mo

    Toyota of Richardson

    4.7
    Richardson, TX (16 mi)
    Check Availability
  • Not Priced

    41,137 mi.
    Est. $0/mo

    Autos of Dallas Irving

    3.0
    Irving, TX (22 mi)
    Check Availability
  • Tan 2022 Lexus RX 350Tan 2022 Lexus RX 350Tan 2022 Lexus RX 350Tan 2022 Lexus RX 350Tan 2022 Lexus RX 350Tan 2022 Lexus RX 350

    $39,998

    50,520 mi.
    Est. $738/mo

    CarMax Kenner

    4.5
    $299 delivery to Denton, TX (11 mi)
    Check Availability
  • Gray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT Handling

    $48,315

    13,512 mi.
    Est. $892/mo

    Jim Butler Centralia

    4.0
    Free delivery from Centralia, MO (496 mi)
    Check Availability
  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $31,093

    $2.1K
    84,798 mi.
    Est. $574/mo

    Autobahn Volvo Fort Worth

    4.3
    Fort Worth, TX (39 mi)
    Check Availability
  • Matador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 Base

    $43,920

    27,072 mi.
    Est. $811/mo

    Sewell Lexus of Fort Worth

    3.8
    Fort Worth, TX (45 mi)
    Check Availability
  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $39,919

    $1.5K
    52,204 mi.
    Est. $737/mo

    Vandergriff Acura

    3.1
    Arlington, TX (36 mi)
    Check Availability
  • $35,504

    $426
    65,718 mi.
    Est. $655/mo

    Autobahn BMW Fort Worth

    4.5
    Fort Worth, TX (38 mi)
    Check Availability
  • Beige / Tan 2022 Lexus RX 350 Base

    Not Priced

    35,195 mi.
    Est. $0/mo

    Toyota of Fort Worth

    4.6
    White Settlement, TX (44 mi)
    Check Availability

Lexus RX 350 prices by year

Model year Average price Deals
2027 Lexus RX 350 $64,740
2026 Lexus RX 350 $62,151 14 Good deals
2025 Lexus RX 350 $55,557 15 Great deals
2024 Lexus RX 350 $50,139 13 Great deals
2023 Lexus RX 350 $44,533 7 Great deals
2021 Lexus RX 350 $33,824 5 Great deals
2020 Lexus RX 350 $32,181 11 Good deals
2018 Lexus RX 350 $28,288 5 Great deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $38,164, with pricing starting at $25,120.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

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