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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $35,998

    31,212 mi.
    Est. $670/mo

    CarMax Phoenix-Gilbert

    4.6
    Check Availability
    Gilbert, AZ (28 mi)
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  • Atomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 Base

    $32,184

    78,343 mi.
    Est. $599/mo

    Mercedes-Benz of North Scottsdale

    4.9
    Check Availability
    Phoenix, AZ (12 mi)
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  • Atomic Silver 2021 Lexus RX 350 Base

    $39,981

    38,994 mi.
    Est. $744/mo

    Scottsdale Mitsubishi

    4.0
    Check Availability
    Scottsdale, AZ (14 mi)
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  • $29,728

    92,974 mi.
    Est. $553/mo

    Henry Brown Buick GMC

    4.8
    Check Availability
    Gilbert, AZ (28 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $35,998

    44,397 mi.
    Est. $670/mo

    CarMax Irvine

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    $99 delivery to Tolleson, AZ (13 mi)
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  • Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350

    $33,998

    55,625 mi.
    Est. $632/mo

    CarMax Canoga Park

    4.6
    Check Availability
    $99 delivery to Tolleson, AZ (13 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $35,998

    44,397 mi.
    Est. $670/mo

    CarMax Irvine

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    Irvine, CA (325 mi)
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  • Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350

    $33,998

    55,625 mi.
    Est. $632/mo

    CarMax Canoga Park

    4.6
    Check Availability
    Canoga Park, CA (376 mi)
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  • Ultra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT Appearance

    $37,500

    55,293 mi.
    Est. $698/mo

    Arroyo Grande Chevrolet

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    Arroyo Grande, CA (496 mi)
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  • Ultra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT Handling

    $37,990

    61,447 mi.
    Est. $707/mo

    Fletcher Jones Imports

    4.6
    Check Availability
    Las Vegas, NV (253 mi)
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  • Nightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 Base

    $39,973

    $800
    20,062 mi.
    Est. $744/mo

    Bill Luke Marana

    4.5
    Check Availability
    Tucson, AZ (100 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $34,208

    $790
    45,984 mi.
    Est. $636/mo

    Wondries Toyota

    4.6
    Check Availability
    Alhambra, CA (349 mi)
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  • Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350

    $35,998

    39,099 mi.
    Est. $670/mo

    CarMax Palm Desert

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    Palm Desert, CA (247 mi)
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  • White 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 L

    $36,998

    45,335 mi.
    Est. $688/mo

    CarMax Buena Park

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    Buena Park, CA (341 mi)
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  • Ultra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT Handling

    $41,952

    40,429 mi.
    Est. $780/mo

    Lexus of Cerritos

    4.7
    Check Availability
    Cerritos, CA (346 mi)
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  • Black 2021 Lexus RX 350 BaseBlack 2021 Lexus RX 350 BaseBlack 2021 Lexus RX 350 BaseBlack 2021 Lexus RX 350 BaseBlack 2021 Lexus RX 350 BaseBlack 2021 Lexus RX 350 Base

    $28,500

    88,225 mi.
    Est. $530/mo

    Nextcar Motor

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    Rosemead, CA (347 mi)
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  • Gray 2021 Lexus RX 350 F SPORT HandlingGray 2021 Lexus RX 350 F SPORT HandlingGray 2021 Lexus RX 350 F SPORT HandlingGray 2021 Lexus RX 350 F SPORT HandlingGray 2021 Lexus RX 350 F SPORT HandlingGray 2021 Lexus RX 350 F SPORT Handling

    $37,395

    65,346 mi.
    Est. $696/mo

    Action Auto Sales and Finance Inc.

    3.8
    Check Availability
    Lehi, UT (467 mi)
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  • Nightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 BaseNightfall Mica 2021 Lexus RX 350 Base

    $31,599

    60,485 mi.
    Est. $588/mo

    California Motor Trade 3

    3.2
    Check Availability
    Norco, CA (315 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $60,897 2 Good deals
2024 Lexus RX 350 $50,057 9 Good deals
2023 Lexus RX 350 $49,334 7 Good deals

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $36,129, with pricing starting at $25,450.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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