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  • Eminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT Handling

    $48,500

    $1.5K
    42,987 mi.
    Est. $876/mo

    Fred Anderson Kia of Greer

    4.4
    Check Availability
    Greer, SC (13 mi)
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  • Atomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium Plus

    $42,995

    40,229 mi.
    Est. $777/mo

    Nodine Motor

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    Inman, SC (23 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium Plus

    $52,367

    $1.4K
    14,273 mi.
    Est. $946/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Caviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 Premium

    $51,995

    $192
    7,600 mi.
    Est. $940/mo

    Fred Anderson Toyota of Greer

    3.6
    Check Availability
    Greer, SC (14 mi)
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  • Caviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 Premium

    $48,767

    21,778 mi.
    Est. $881/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • EMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 Premium

    $27,995

    76,885 mi.
    Est. $506/mo

    Nodine Motor

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    Inman, SC (23 mi)
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  • Nightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 Luxury

    $55,767

    $2K
    12,236 mi.
    Est. $1,008/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Matador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT Handling

    $41,767

    $1.2K
    52,101 mi.
    Est. $755/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $35,383

    $163
    44,838 mi.
    Est. $639/mo

    Escude Nissan of Greer

    4.3
    Check Availability
    Greer, SC (14 mi)
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  • Ultra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT Design

    $57,767

    $1K
    2,079 mi.
    Est. $1,044/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Iridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT Design

    $56,767

    $1K
    9,632 mi.
    Est. $1,026/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Nebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium Plus

    $44,767

    $1.6K
    45,788 mi.
    Est. $809/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Iridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 Premium

    $49,767

    $1K
    19,685 mi.
    Est. $899/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Satin Cashmere Metallic 2015 Lexus RX 350 PremiumSatin Cashmere Metallic 2015 Lexus RX 350 PremiumSatin Cashmere Metallic 2015 Lexus RX 350 PremiumSatin Cashmere Metallic 2015 Lexus RX 350 PremiumSatin Cashmere Metallic 2015 Lexus RX 350 PremiumSatin Cashmere Metallic 2015 Lexus RX 350 Premium

    $14,367

    149,888 mi.
    Est. $260/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $41,767

    40,398 mi.
    Est. $755/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $46,767

    $601
    37,738 mi.
    Est. $845/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Black 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 Base

    $24,499

    83,004 mi.
    Est. $443/mo

    Steve White Audi Volkswagen Volvo Greenville

    4.6
    Check Availability
    Greenville, SC (4 mi)
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  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $37,367

    $1.4K
    61,188 mi.
    Est. $675/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Copper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium Plus

    $47,367

    29,096 mi.
    Est. $856/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (3 mi)
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  • Satin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 BaseSatin Cashmere Metallic 2017 Lexus RX 350 Base

    $23,259

    $738
    110,643 mi.
    Est. $420/mo

    Hendrick Honda of Easley

    4.8
    Check Availability
    Easley, SC (9 mi)
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  • Blue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT Appearance

    $32,395

    $4K
    49,257 mi.
    Est. $585/mo

    Century BMW

    4.8
    Check Availability
    Greenville, SC (4 mi)
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  • Nebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F Sport

    $29,500

    $200
    91,473 mi.
    Est. $533/mo

    McKinney Dodge Ram Chrysler Jeep

    4.9
    Check Availability
    Easley, SC (8 mi)
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  • Blue 2022 Lexus RX 350Blue 2022 Lexus RX 350Blue 2022 Lexus RX 350Blue 2022 Lexus RX 350Blue 2022 Lexus RX 350Blue 2022 Lexus RX 350

    $41,998

    46,393 mi.
    Est. $759/mo

    CarMax Cool Springs

    Check Availability
    $199 delivery to Greenville, SC (4 mi)
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  • Gray 2023 Lexus RX 350 Premium PlusGray 2023 Lexus RX 350 Premium PlusGray 2023 Lexus RX 350 Premium PlusGray 2023 Lexus RX 350 Premium PlusGray 2023 Lexus RX 350 Premium PlusGray 2023 Lexus RX 350 Premium Plus

    $45,998

    $1K
    26,385 mi.
    Est. $831/mo

    CarMax Roanoke

    Check Availability
    $299 delivery to Greenville, SC (4 mi)
    Quick view

Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,333
2025 Lexus RX 350 $57,007 3 Good deals
2023 Lexus RX 350 $50,267 2 Good deals

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $34,998, with pricing starting at $350.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2008 to 2026.

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