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  • Gray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT Handling

    $44,697

    53,747 mi.
    Est. $808/mo

    Subaru of Spartanburg

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    Spartanburg, SC (25 mi)
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  • EMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 Premium

    $27,995

    76,885 mi.
    Est. $506/mo

    Nodine Motor

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    Inman, SC (23 mi)
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  • White Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 Base

    $34,679

    109,278 mi.
    Est. $627/mo

    INFINITI of Greenville

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    Greenville, SC (4 mi)
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  • Classic Silver Metallic 2009 Lexus RX 350 BaseClassic Silver Metallic 2009 Lexus RX 350 BaseClassic Silver Metallic 2009 Lexus RX 350 BaseClassic Silver Metallic 2009 Lexus RX 350 BaseClassic Silver Metallic 2009 Lexus RX 350 BaseClassic Silver Metallic 2009 Lexus RX 350 Base

    $9,269

    128,480 mi.
    Est. $168/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Iridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 Luxury

    $54,767

    $600
    21,422 mi.
    Est. $990/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Atomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 Base

    $31,118

    106,183 mi.
    Est. $562/mo

    Fred Anderson Honda

    4.6
    Check Availability
    Greenville, SC (5 mi)
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  • Silver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 Premium

    $23,367

    $400
    98,075 mi.
    Est. $422/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Black 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 Base

    $25,489

    51,675 mi.
    Est. $461/mo

    Kevin Whitaker Chevrolet

    4.4
    Check Availability
    Greenville, SC (5 mi)
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  • Matador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium Plus

    $51,767

    $1K
    35,021 mi.
    Est. $936/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $44,767

    $1K
    54,915 mi.
    Est. $809/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $36,491

    44,838 mi.
    Est. $659/mo

    Escude Nissan of Greer

    4.3
    Check Availability
    Greer, SC (13 mi)
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  • Cloudburst Gray 2024 Lexus RX 350 PremiumCloudburst Gray 2024 Lexus RX 350 PremiumCloudburst Gray 2024 Lexus RX 350 PremiumCloudburst Gray 2024 Lexus RX 350 PremiumCloudburst Gray 2024 Lexus RX 350 PremiumCloudburst Gray 2024 Lexus RX 350 Premium

    $53,767

    $1K
    21,104 mi.
    Est. $972/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Iridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT Design

    $55,767

    $1K
    9,632 mi.
    Est. $1,008/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $36,767

    $600
    61,188 mi.
    Est. $664/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Nightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 Luxury

    $55,367

    $400
    12,236 mi.
    Est. $1,001/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Matador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium PlusMatador Red Mica 2023 Lexus RX 350 Premium Plus

    $53,767

    $1K
    28,588 mi.
    Est. $972/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Iridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 Premium

    $49,367

    $400
    19,685 mi.
    Est. $892/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Copper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium Plus

    $46,367

    $400
    29,110 mi.
    Est. $838/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium Plus

    $51,767

    $600
    14,273 mi.
    Est. $936/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • Nebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium Plus

    $44,367

    $400
    45,788 mi.
    Est. $802/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (4 mi)
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  • White Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 Premium

    $52,199

    12,370 mi.
    Est. $943/mo

    Toyota of Easley

    4.7
    Check Availability
    Easley, SC (16 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $31,998

    $1K
    67,490 mi.
    Est. $578/mo

    CarMax Greenville

    2.6
    Check Availability
    Greenville, SC (3 mi)
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  • Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350

    $37,998

    38,840 mi.
    Est. $687/mo

    CarMax Tupelo

    Check Availability
    $349 delivery to Greenville, SC (3 mi)
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  • Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350

    $38,998

    38,535 mi.
    Est. $705/mo

    CarMax Myrtle Beach

    4.7
    Check Availability
    $99 delivery to Greenville, SC (3 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,146
2025 Lexus RX 350 $57,189 2 Good deals
2023 Lexus RX 350 $51,537 7 Good deals

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $35,317, with pricing starting at $999.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2008 to 2026.

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