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  • White Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 PremiumWhite Pearl 2024 Lexus RX 350 Premium

    $52,199

    $251
    12,370 mi.
    Est. $943/mo

    Toyota of Easley

    4.7
    Check Availability
    Easley, SC (11 mi)
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  • Nebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F SportNebula Gray Pearl 2020 Lexus RX 350 F Sport

    $29,500

    $200
    91,473 mi.
    Est. $533/mo

    McKinney Dodge Ram Chrysler Jeep

    4.9
    Check Availability
    Easley, SC (9 mi)
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  • Black 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 Base

    $24,499

    83,004 mi.
    Est. $443/mo

    Steve White Audi Volkswagen Volvo Greenville

    4.6
    Check Availability
    Greenville, SC (8 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT Handling

    $49,099

    42,987 mi.
    Est. $887/mo

    Fred Anderson Kia of Greer

    4.4
    Check Availability
    Greer, SC (12 mi)
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  • Black 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 BaseBlack 2015 Lexus RX 350 Base

    $24,990

    51,675 mi.
    Est. $452/mo

    Kevin Whitaker Chevrolet

    4.4
    Check Availability
    Greenville, SC (6 mi)
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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $35,099

    $447
    44,838 mi.
    Est. $634/mo

    Escude Nissan of Greer

    4.3
    Check Availability
    Greer, SC (12 mi)
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  • EMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 PremiumEMINENT PEARL WHITE 2016 Lexus RX 350 Premium

    $27,995

    76,885 mi.
    Est. $506/mo

    Nodine Motor

    Check Availability
    Inman, SC (21 mi)
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  • Iridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT Design

    $56,767

    $1K
    9,632 mi.
    Est. $1,026/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $40,767

    $1K
    40,398 mi.
    Est. $737/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Iridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 Premium

    $49,767

    $1K
    19,685 mi.
    Est. $899/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Nebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium Plus

    $44,767

    $1.6K
    45,788 mi.
    Est. $809/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Caviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 Premium

    $48,767

    21,779 mi.
    Est. $881/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Matador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT Handling

    $41,767

    52,101 mi.
    Est. $755/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium Plus

    $52,367

    $1.4K
    14,273 mi.
    Est. $946/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • White Pearl 2017 Lexus RX 350 BaseWhite Pearl 2017 Lexus RX 350 BaseWhite Pearl 2017 Lexus RX 350 BaseWhite Pearl 2017 Lexus RX 350 BaseWhite Pearl 2017 Lexus RX 350 BaseWhite Pearl 2017 Lexus RX 350 Base

    $22,981

    116,805 mi.
    Est. $415/mo

    Toyota of Greenville

    4.7
    Check Availability
    Greenville, SC (7 mi)
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  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $37,367

    $1.4K
    61,188 mi.
    Est. $675/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 PremiumEminent White Pearl 2021 Lexus RX 350 PremiumEminent White Pearl 2021 Lexus RX 350 PremiumEminent White Pearl 2021 Lexus RX 350 PremiumEminent White Pearl 2021 Lexus RX 350 PremiumEminent White Pearl 2021 Lexus RX 350 Premium

    $40,767

    51,910 mi.
    Est. $737/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Iridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 LuxuryIridium 2023 Lexus RX 350 Luxury

    $56,767

    21,422 mi.
    Est. $1,026/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $46,767

    $4K
    21,369 mi.
    Est. $845/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Silver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 PremiumSilver Lining Metallic 2016 Lexus RX 350 Premium

    $24,367

    98,075 mi.
    Est. $440/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
    Quick view
  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $45,767

    $1K
    37,738 mi.
    Est. $827/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
    Quick view
  • Ultra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT DesignUltra White 2025 Lexus RX 350 F SPORT Design

    $57,767

    $1K
    2,079 mi.
    Est. $1,044/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (7 mi)
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  • Silver 2015 Lexus RX 350Silver 2015 Lexus RX 350Silver 2015 Lexus RX 350Silver 2015 Lexus RX 350Silver 2015 Lexus RX 350Silver 2015 Lexus RX 350

    $18,998

    109,866 mi.
    Est. $343/mo

    CarMax Chattanooga

    Check Availability
    $199 delivery to Greenville, SC (8 mi)
    Quick view
  • White 2020 Lexus RX 350White 2020 Lexus RX 350White 2020 Lexus RX 350White 2020 Lexus RX 350White 2020 Lexus RX 350White 2020 Lexus RX 350

    $41,998

    20,251 mi.
    Est. $759/mo

    CarMax Chattanooga

    Check Availability
    $199 delivery to Greenville, SC (8 mi)
    Quick view

Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,069
2025 Lexus RX 350 $57,007 2 Good deals
2023 Lexus RX 350 $51,479 1 Good deal

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $35,164, with pricing starting at $3,400.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2008 to 2026.

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