2006 Lexus IS 350

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Key specs

Base trim shown


Body style


Seating capacity

180.1” x 56.1”


Rear-wheel drive



1 trim

Starting msrp listed lowest to highest price

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Our 2006 Lexus IS 350 trim comparison will help you decide.

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2006 Lexus IS 350 review: Our expert's take

By Bob Golfen

Lexus performed major surgery on its IS sport sedan for 2006, boosting power and precision while laying on a larger measure of refinement.

Completely revamped, the new IS 250 and IS 350 turned out to be performance compacts of the first order, challenging undisputed segment leader BMW 3-Series in agility and image. The high-tech V-6 found in the IS 350 trumps its comparable classmates for raw horsepower. The new IS models replace the well-regarded IS 300, which gradually lost its luster during its five-year run. IS stands as the smallest Lexus model, an entry-level sedan for upwardly mobile buyers, and the brass at Toyota’s luxury division felt it was falling behind the rest of the brand’s high-end offerings. IS gains a few inches in all dimensions, with an aggressive new body style, new chassis and suspension for improved handling and response, and a well-tailored interior with added features and refinement. I drove the IS 350, which proved to be a fast and sophisticated machine with superb handling, nimble steering and awesome brakes. Though lacking the sharp response of BMW, the Lexus had the poise and maneuverability that driving enthusiasts crave. IS 350 comes standard with a sequential six-speed automatic with Formula One-style paddle shifters behind the steering wheel for fingertip control. This high-tech transmission adds to the performance flavor, although serious drivers will miss the lack of a regular manual transmission. That is available only on the less-potent IS 250. Too bad.

PERFORMANCE: For 2006, IS loses its 215-horsepower inline six for a pair of all new V-6 engines: a free-revving 2.5 liter with 204 horsepower in the IS 250 and a 3.5 liter with a romping 306 horsepower. That compares with 255 horsepower for the inline six in the BMW 330i. IS 350 accelerates like a muscle car, only silky smooth. A super-nice engine with an even flow of power throughout the rpm range. Fuel economy is decent, too. The sequential-shift transmission produces fast and precise gear changes in either automatic or manual mode. Oddly, when you shift from automatic to manual, the transmission puts the car in fourth gear, even if you’ve been hurtling along in sixth. Abrupt and annoying.

DRIVABILITY: This nicely balanced rear-drive sedan delivers satisfying handling whether you’re on a crowded city street or a winding back road. The IS 350 comes loaded with electronic goodies, including Toyota’s excellent Vehicle Dynamics Integrated Management. The system is seamless and nearly imperceptible and makes you feel like a much better driver than you really are. The test car came with an optional Pre-Collision System that senses whether a crash is imminent, retracting the seat belts and preparing to apply full brake assist. Fortunately, I never tried that out. Other features include traction control, anti-lock brakes, backup camera, side and knee-bolster air bags and tire-pressure monitor. The steering is precise but has a numb feel.

STYLING: A nice update for IS, looking suitably fast and fairly furious.

INTERIOR: A smartly refined cabin with supportive seats, impressive trim and all the comfort and convenience features you could dream up. The dashboard is a pretty busy place, though, with a distracting aura of gadgetry.

BOTTOM LINE: A generally excellent machine with no disappointments, although the options on the test car pushed the price tag into premium territory.

Lexus IS 350

Vehicle type: Five-passenger, four-door sedan, rear-wheel drive. Engine: 3.5-liter V-6, 306 horsepower at 6,400 rpm, 277 pound-feet torque at 4,800 rpm. Transmission: 6-speed automatic. Wheelbase: 107.5 inches. Overall length: 180.1 inches. Curb weight: 3,527 pounds. EPA rating: 21 city, 28 highway

Highs: Powerful engine, precise handling, luxury interior. Lows: Gadgety dashboard, pricey with options, no stick shift with bigger engine.

Pricing Base price: $35,440. Price as tested: $47,713.

SELECTED OPTIONS — Luxury package, including 18-inch alloy wheels, adaptive front lighting, leather-seat upgrades, wood trim, power tilt and telescoping steering wheel, power rear sunshade, rain-sensing wipers, $4,215. — Navigation system, premium 14-speaker audio system, DVD video, $3,990. — Pre-collision system, adaptive cruise control, $2,850. — Park assist with front and rear sensors, $500. — Shipping, $590.

Consumer reviews

Rating breakdown (out of 5):
  • Comfort 4.5
  • Interior 4.8
  • Performance 4.9
  • Value 4.7
  • Exterior 5.0
  • Reliability 4.9

Most recent consumer reviews


Absolutely the best car I have ever owned.

I bought this car in 2006 with 7K miles. It is absolutely the best car I have ever owned. It is now 16 years old and has 180K miles on it. I have only replaced the shocks, the wheels( discount tire) and 1 differential. The oil runs clean right up to the oil change. Beautiful and fast with the upgraded stereo system that sounds like a concert haul. I hate to get rid of it. I enjoy every time I drive it, still.


Powerful and reliable

Let me start by saying this is my first Lexus. All my other vehicles are Toyota’s. This car is my commuter/fun time car. I bought it salvaged with 200,000 plus miles. I bought it cheap! I dumped about 4 grand into styling (Front bumper swap is a must) all the fluids, tires, some cosmetic upgrades, suspension upgrades and maintenance items. This car is a runner and will either beat or hang with V-8’s. I put headers, full dual exhaust and a RR Racing tune. It’ll snap your head back. I can’t believe what I’ve been missing out on. All the luxury I need plus the power. I test drove the ES and loved the smoothness and ride, if pure comfort is what you want with good power get the ES, but if you don’t mind a stiffer ride and a smaller back seat then this is the car for you. I put lowering springs too and the stance is amazing RSR brand was my choice. I don’t scrape but I’m mot that low, the tires do rub but I also have 20’s.


Best car I've ever owned! I've had her for 13yrs!

Sporty, fun, sexy pearl white Lexus IS350 has treated me so well over the past 13+ years and sadly, I must let her go for a mom-mobile! She comes equipped with the most amazing Mark Levinson premium surround sound stereo system thats sure to get you going for a night out on the town! 3 chrome dipped stock Lexus wheels and one alloy that replaced a damaged wheel after a blowout. Chrome dipping can be done for about $300. She's been well maintained and has had every recall rectified by a certified Lexus dealership. She was in a minor fender bender, when I rear ended a small truck going about 5-10 mph. KBB/NADA value of $8100-$10,000 is inclusive of every flaw listed here! There is NOTHING like her for sale in the Nation! She has Every option available...MSRP NEW was $45,000! This color combo is very sought after. I received full cash offers last year and I know the market for used vehicles is way more hot now, due to COVID! New tires and recent front end alignment. Wish I could keep her as an extra car!

See all 28 consumer reviews


New car and Certified Pre-Owned programs by Lexus
New car program benefits
48 months/50,000 miles
72 months/unlimited distance
72 months/70,000 miles
Roadside assistance
48 months/unlimited distance
Certified Pre-Owned program benefits
Maximum age/mileage
2 years/unlimited miles from your certified vehicle date of purchase.
Basic warranty terms
2 years/unlimited miles from your certified vehicle date of purchase. Coverage begins after completion of the 4-year/50,000 new vehicle Basic Warranty.
Dealer certification required
161-point inspection
Roadside assistance
View all cpo program details

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