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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $27,999

    104,894 mi.
    Est. $525/mo

    Lexus of Birmingham

    4.9
    Check Availability
    Irondale, AL (9 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $38,998

    39,674 mi.
    Est. $731/mo

    CarMax Birmingham

    Check Availability
    Hoover, AL (12 mi)
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  • 2021 Lexus RX 350 Base

    $25,495

    138,030 mi.
    Est. $478/mo

    King Acura

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    Birmingham, AL (10 mi)
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  • Nebula Gray Pearl 2021 Lexus RX 350 Base

    $28,999

    102,487 mi.
    Est. $544/mo

    BMW Mini of Birmingham

    4.6
    Check Availability
    Irondale, AL (8 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $36,998

    42,851 mi.
    Est. $694/mo

    CarMax Charleston

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    $299 delivery to Hoover, AL (12 mi)
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  • White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350

    $35,998

    $1K
    53,749 mi.
    Est. $675/mo

    CarMax Gainesville

    Check Availability
    $249 delivery to Hoover, AL (12 mi)
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  • Blue 2021 Lexus RX 350 BaseBlue 2021 Lexus RX 350 BaseBlue 2021 Lexus RX 350 BaseBlue 2021 Lexus RX 350 BaseBlue 2021 Lexus RX 350 BaseBlue 2021 Lexus RX 350 Base

    $32,588

    77,580 mi.
    Est. $611/mo

    Pigg Enterprises Inc

    4.9
    Check Availability
    Prattville, AL (77 mi)
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  • Nebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 Base

    $31,659

    84,436 mi.
    Est. $594/mo

    Stivers Lincoln of Montgomery

    Check Availability
    Montgomery, AL (89 mi)
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  • 2021 Lexus RX 350 Base2021 Lexus RX 350 Base2021 Lexus RX 350 Base2021 Lexus RX 350 Base2021 Lexus RX 350 Base2021 Lexus RX 350 Base

    $42,995

    32,148 mi.
    Est. $806/mo

    Lexus of Huntsville

    4.8
    Check Availability
    Huntsville, AL (86 mi)
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  • Tan 2021 Lexus RX 350 BaseTan 2021 Lexus RX 350 BaseTan 2021 Lexus RX 350 BaseTan 2021 Lexus RX 350 BaseTan 2021 Lexus RX 350 BaseTan 2021 Lexus RX 350 Base

    $32,488

    75,691 mi.
    Est. $609/mo

    Pigg Enterprises Inc

    4.9
    Check Availability
    Prattville, AL (77 mi)
    Quick view
  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $35,984

    $510
    56,968 mi.
    Est. $675/mo

    Lexus of Montgomery

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    Montgomery, AL (87 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $59,828
2025 Lexus RX 350 $56,720
2023 Lexus RX 350 $46,063 6 Good deals

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $35,648, with pricing starting at $25,495.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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