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  • Blue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT Appearance

    $37,397

    $501
    49,257 mi.
    Est. $682/mo

    Century BMW

    4.8
    Check Availability
    Greenville, SC (25 mi)
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  • Autumn Shimmer 2017 Lexus RX 350 BaseAutumn Shimmer 2017 Lexus RX 350 BaseAutumn Shimmer 2017 Lexus RX 350 BaseAutumn Shimmer 2017 Lexus RX 350 BaseAutumn Shimmer 2017 Lexus RX 350 BaseAutumn Shimmer 2017 Lexus RX 350 Base

    $27,949

    76,628 mi.
    Est. $510/mo

    Wakefield Automotive GMC

    5.0
    Check Availability
    Spartanburg, SC (4 mi)
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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $37,727

    $690
    44,826 mi.
    Est. $688/mo

    Escude Nissan of Greer

    4.4
    Check Availability
    Greer, SC (15 mi)
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  • Atomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium Plus

    $43,995

    40,229 mi.
    Est. $803/mo

    Nodine Motor

    Check Availability
    Inman, SC (8 mi)
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  • Starfire Pearl 2014 Lexus RX 350 BaseStarfire Pearl 2014 Lexus RX 350 BaseStarfire Pearl 2014 Lexus RX 350 BaseStarfire Pearl 2014 Lexus RX 350 BaseStarfire Pearl 2014 Lexus RX 350 BaseStarfire Pearl 2014 Lexus RX 350 Base

    $9,900

    227,100 mi.
    Est. $181/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • White 2011 Lexus RX 350 BaseWhite 2011 Lexus RX 350 BaseWhite 2011 Lexus RX 350 BaseWhite 2011 Lexus RX 350 BaseWhite 2011 Lexus RX 350 BaseWhite 2011 Lexus RX 350 Base

    $10,997

    $401
    124,510 mi.
    Est. $201/mo

    Century BMW

    4.8
    Check Availability
    Greenville, SC (25 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $44,998

    $1K
    40,398 mi.
    Est. $821/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Matador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT Handling

    $45,598

    $1K
    52,101 mi.
    Est. $832/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Cloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 Premium

    $52,398

    $600
    9,440 mi.
    Est. $956/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Cloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 Premium

    $53,598

    $1K
    6,582 mi.
    Est. $978/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $37,998

    $3.9K
    41,748 mi.
    Est. $693/mo

    INFINITI of Greenville

    Check Availability
    Greenville, SC (25 mi)
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  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $41,998

    48,546 mi.
    Est. $766/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Silver Lining Metallic 2018 Lexus RX 350 PremiumSilver Lining Metallic 2018 Lexus RX 350 Premium

    $26,598

    93,570 mi.
    Est. $485/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Caviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium Plus

    $46,398

    28,582 mi.
    Est. $846/mo

    Century BMW

    4.8
    Check Availability
    Greenville, SC (25 mi)
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  • Eminent White Pearl 2017 Lexus RX 350 BaseEminent White Pearl 2017 Lexus RX 350 BaseEminent White Pearl 2017 Lexus RX 350 BaseEminent White Pearl 2017 Lexus RX 350 BaseEminent White Pearl 2017 Lexus RX 350 BaseEminent White Pearl 2017 Lexus RX 350 Base

    $28,995

    55,553 mi.
    Est. $529/mo

    Steve White Audi Volkswagen Volvo Greenville

    4.7
    Check Availability
    Greenville, SC (25 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $49,998

    24,560 mi.
    Est. $912/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Gold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 Base

    $9,995

    179,160 mi.
    Est. $182/mo

    Auto-Fleet

    Check Availability
    Spartanburg, SC (2 mi)
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  • Eminent White Pearl 2020 Lexus RX 350 PremiumEminent White Pearl 2020 Lexus RX 350 PremiumEminent White Pearl 2020 Lexus RX 350 PremiumEminent White Pearl 2020 Lexus RX 350 PremiumEminent White Pearl 2020 Lexus RX 350 PremiumEminent White Pearl 2020 Lexus RX 350 Premium

    $38,998

    40,236 mi.
    Est. $711/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Silver 2024 Lexus RX 350 Premium PlusSilver 2024 Lexus RX 350 Premium PlusSilver 2024 Lexus RX 350 Premium PlusSilver 2024 Lexus RX 350 Premium PlusSilver 2024 Lexus RX 350 Premium PlusSilver 2024 Lexus RX 350 Premium Plus

    $54,998

    18,639 mi.
    Est. $1,003/mo

    CarMax Greenville

    2.2
    Check Availability
    Greenville, SC (25 mi)
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  • Cloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 PremiumCloudburst Gray 2025 Lexus RX 350 Premium

    $53,998

    $1K
    6,161 mi.
    Est. $985/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (25 mi)
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  • Black 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 BaseBlack 2017 Lexus RX 350 Base

    $25,499

    $500
    83,004 mi.
    Est. $465/mo

    Steve White Audi Volkswagen Volvo Greenville

    4.7
    Check Availability
    Greenville, SC (25 mi)
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  • Claret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 BaseClaret Mica 2015 Lexus RX 350 Base

    $17,398

    114,500 mi.
    Est. $317/mo

    Genesis Of Greer

    3.6
    Check Availability
    Greer, SC (14 mi)
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  • Gray 2017 Lexus RX 350 RX 350Gray 2017 Lexus RX 350 RX 350Gray 2017 Lexus RX 350 RX 350Gray 2017 Lexus RX 350 RX 350Gray 2017 Lexus RX 350 RX 350Gray 2017 Lexus RX 350 RX 350

    $25,998

    82,373 mi.
    Est. $474/mo

    CarMax Chattanooga

    Check Availability
    $199 delivery to Greenville, SC (25 mi)
    Quick view
  • White 2018 Lexus RX 350White 2018 Lexus RX 350White 2018 Lexus RX 350White 2018 Lexus RX 350White 2018 Lexus RX 350White 2018 Lexus RX 350

    $25,998

    $1K
    97,948 mi.
    Est. $474/mo

    CarMax Jacksonville NC

    Check Availability
    $199 delivery to Greenville, SC (25 mi)
    Quick view

Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,928
2025 Lexus RX 350 $55,945 4 Good deals

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $32,495, with pricing starting at $3,499.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2008 to 2026.

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