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  • Atomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 Base

    $39,391

    $259
    50,608 mi.
    Est. $724/mo

    Lexus of Cerritos

    4.8
    Check Availability
    Cerritos, CA (10 mi)

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  • Cloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 Base

    $37,900

    66,310 mi.
    Est. $696/mo

    Nissan of Tustin

    4.8
    Check Availability
    Tustin, CA (14 mi)
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  • White 2022 Lexus IS 350 F-SportWhite 2022 Lexus IS 350 F-SportWhite 2022 Lexus IS 350 F-SportWhite 2022 Lexus IS 350 F-SportWhite 2022 Lexus IS 350 F-SportWhite 2022 Lexus IS 350 F-Sport

    $38,998

    48,486 mi.
    Est. $716/mo

    CarMax LAX

    Check Availability
    Inglewood, CA (26 mi)
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  • Iridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 Base

    $38,999

    46,637 mi.
    Est. $716/mo

    Fontana Motors Direct

    2.8
    Check Availability
    Fontana, CA (30 mi)
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  • $42,500

    37,118 mi.
    Est. $781/mo

    Ford of Long Beach

    1.8
    Check Availability
    Long Beach, CA (13 mi)
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  • Cloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 Base

    $40,990

    42,137 mi.
    Est. $753/mo

    Unlimited Motors

    4.5
    Check Availability
    $2,690 delivery from Westfield, IN (1794 mi)
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  • Blue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-SportBlue 2022 Lexus IS 350 F-Sport

    $44,998

    $1K
    5,994 mi.
    Est. $827/mo

    CarMax Fremont

    Check Availability
    $149 delivery to Buena Park, CA (5 mi)
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  • Cloudburst Gray 2022 Lexus IS 350 F SportCloudburst Gray 2022 Lexus IS 350 F SportCloudburst Gray 2022 Lexus IS 350 F SportCloudburst Gray 2022 Lexus IS 350 F SportCloudburst Gray 2022 Lexus IS 350 F SportCloudburst Gray 2022 Lexus IS 350 F Sport

    $43,747

    $399
    24,794 mi.
    Est. $804/mo

    Findlay Honda in Centennial Hills

    4.8
    Check Availability
    Las Vegas, NV (224 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $42,997

    34,544 mi.
    Est. $790/mo

    Porsche Fresno

    4.8
    Check Availability
    Fresno, CA (230 mi)
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  • Atomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 Base

    $44,251

    $3.3K
    24,519 mi.
    Est. $813/mo

    Lexus Santa Monica

    4.0
    Check Availability
    Santa Monica, CA (34 mi)
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  • Caviar 2022 Lexus IS 350 Base

    $44,585

    28,930 mi.
    Est. $819/mo

    AutoNation CDJR Carlsbad

    4.7
    Check Availability
    Carlsbad, CA (64 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $51,234 1 Good deal
2025 Lexus IS 350 $48,608 6 Good deals
2024 Lexus IS 350 $44,487 7 Good deals
2023 Lexus IS 350 $42,976 14 Great deals

About the 2022 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus IS 350
FAQs

How much does the 2022 Lexus IS 350 cost?

The 2022 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 IS 350 is $41,015, with pricing starting at $30,994.

What is the MPG of the 2022 Lexus IS 350?

The 2022 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2022 Lexus IS 350 reliable?

The 2022 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 IS 350 owners.

Is the 2022 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2022 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
4.5
Interior
4.5
Performance
4.5
Value
4.0
Exterior
4.5
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.5
Interior
4.5
Performance
4.5
Value
4.0
Exterior
4.5
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $43,550 Starting at $45,550
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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