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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $40,660

    $1K
    35,678 mi.
    Est. $709/mo

    Grand Prairie Ford

    4.7
    Check Availability
    Grand Prairie, TX (28 mi)
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  • Atomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 BaseAtomic Silver 2022 Lexus IS 350 Base

    $38,552

    66,621 mi.
    Est. $672/mo

    AutoNation Chrysler Dodge Jeep Ram North Fort Worth

    4.6
    Check Availability
    Fort Worth, TX (29 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $38,995

    92,799 mi.
    Est. $680/mo

    Imd Motors Richardson

    Check Availability
    Dallas, TX (17 mi)
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  • Grecian Water 2022 Lexus IS 350 F SportGrecian Water 2022 Lexus IS 350 F SportGrecian Water 2022 Lexus IS 350 F SportGrecian Water 2022 Lexus IS 350 F SportGrecian Water 2022 Lexus IS 350 F SportGrecian Water 2022 Lexus IS 350 F Sport

    $39,265

    $260
    55,257 mi.
    Est. $685/mo

    Grubbs Acura

    3.5
    Check Availability
    Grapevine, TX (19 mi)
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  • Silver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F Sport

    $40,436

    $300
    46,120 mi.
    Est. $705/mo

    Bishop Maserati

    3.5
    Check Availability
    Hurst, TX (30 mi)
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  • Iridium 2022 Lexus IS 350 F SportIridium 2022 Lexus IS 350 F SportIridium 2022 Lexus IS 350 F SportIridium 2022 Lexus IS 350 F SportIridium 2022 Lexus IS 350 F SportIridium 2022 Lexus IS 350 F Sport

    $39,775

    $250
    55,066 mi.
    Est. $693/mo

    Grubbs Volvo Cars Grapevine

    4.6
    Check Availability
    Grapevine, TX (19 mi)
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  • Silver 2022 Lexus IS 350 BaseSilver 2022 Lexus IS 350 BaseSilver 2022 Lexus IS 350 BaseSilver 2022 Lexus IS 350 BaseSilver 2022 Lexus IS 350 BaseSilver 2022 Lexus IS 350 Base

    $43,990

    36,589 mi.
    Est. $767/mo

    Audi Plano

    4.8
    Check Availability
    Plano, TX (10 mi)
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  • Silver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F SportSilver 2022 Lexus IS 350 F Sport

    $42,210

    $1.6K
    49,929 mi.
    Est. $736/mo

    Hopper Motorplex

    Check Availability
    Irving, TX (19 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $49,913

    17,695 mi.
    Est. $870/mo

    Sewell Lexus of Dallas

    3.3
    Check Availability
    Dallas, TX (23 mi)
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  • Infrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 Base

    $44,125

    $700
    27,463 mi.
    Est. $769/mo

    Sewell Lexus of Dallas

    3.3
    Check Availability
    Dallas, TX (23 mi)
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  • Infrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 Base

    $38,725

    $488
    73,725 mi.
    Est. $675/mo

    Sewell Lexus of Dallas

    3.3
    Check Availability
    Dallas, TX (23 mi)
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  • $42,217

    39,646 mi.
    Est. $736/mo

    Longo Toyota of Prosper

    4.9
    Check Availability
    Prosper, TX (9 mi)
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  • Infrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 Base

    $43,708

    24,185 mi.
    Est. $762/mo

    Mercedes-Benz of Georgetown

    4.8
    Check Availability
    $399 delivery from Austin, TX (212 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $39,879

    49,317 mi.
    Est. $695/mo

    Unlimited Motors

    4.5
    Check Availability
    $1,141 delivery from Westfield, IN (761 mi)
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  • Iridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 Base

    $44,724

    $1.5K
    20,608 mi.
    Est. $780/mo

    AutoNation Ford South Fort Worth

    4.2
    Check Availability
    Fort Worth, TX (41 mi)
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  • Not Priced

    39,155 mi.
    Est. $0/mo

    Four Stars Toyota

    5.0
    Check Availability
    Altus, OK (173 mi)
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  • $45,822

    21,825 mi.
    Est. $799/mo

    Genesis of Edmond

    4.8
    Check Availability
    OKLAHOMA CITY, OK (174 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $55,506 1 Good deal
2025 Lexus IS 350 $46,882 7 Good deals
2024 Lexus IS 350 $43,137 8 Good deals
2023 Lexus IS 350 $45,309 7 Great deals
2021 Lexus IS 350 $38,166 4 Good deals

About the 2022 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus IS 350
FAQs

How much does the 2022 Lexus IS 350 cost?

The 2022 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 IS 350 is $40,472, with pricing starting at $26,991.

What is the MPG of the 2022 Lexus IS 350?

The 2022 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus IS 350?

The 2022 Lexus IS 350 compares to and/or competes against the following vehicles:


  • Mitsubishi Lancer
  • Lexus IS 500
  • Lexus IS 300
  • Genesis G70
  • BMW M340
  • Acura TLX

Is the 2022 Lexus IS 350 reliable?

The 2022 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 IS 350 owners.

Is the 2022 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2022 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
4.5
Interior
4.5
Performance
4.5
Value
4.0
Exterior
4.5
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.5
Interior
4.5
Performance
4.5
Value
4.0
Exterior
4.5
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $43,550 Starting at $45,550
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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