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  • Cloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 Base

    $40,990

    42,137 mi.
    Est. $741/mo

    Unlimited Motors

    4.5
    Check Availability
    $354 delivery from Westfield, IN (236 mi)
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  • Ultra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 BaseUltra White 2022 Lexus IS 350 Base

    $39,990

    49,314 mi.
    Est. $723/mo

    Unlimited Motors

    4.5
    Check Availability
    $354 delivery from Westfield, IN (236 mi)
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  • incognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Baseincognito 2025 Lexus IS 350 Base

    $50,860

    9,828 mi.
    Est. $919/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (80 mi)
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  • Iridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 BaseIridium 2024 Lexus IS 350 Base

    $50,173

    27,779 mi.
    Est. $907/mo

    Downtown Nashville Nissan

    4.4
    Check Availability
    Nashville, TN (100 mi)
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  • Ultra White 2024 Lexus IS 350 F SportUltra White 2024 Lexus IS 350 F SportUltra White 2024 Lexus IS 350 F SportUltra White 2024 Lexus IS 350 F SportUltra White 2024 Lexus IS 350 F SportUltra White 2024 Lexus IS 350 F Sport

    $48,995

    8,205 mi.
    Est. $885/mo

    Cadillac of Knoxville

    4.1
    Check Availability
    Knoxville, TN (81 mi)
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  • Gray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-Sport

    $39,998

    46,110 mi.
    Est. $723/mo

    CarMax Murfreesboro

    Check Availability
    Murfreesboro, TN (96 mi)
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  • Cloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 BaseCloudburst Gray 2022 Lexus IS 350 Base

    $40,391

    36,420 mi.
    Est. $730/mo

    Mount Juliet Chrysler Dodge Jeep Ram

    Check Availability
    Mt. Juliet, TN (87 mi)
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  • Caviar 2024 Lexus IS 350 BaseCaviar 2024 Lexus IS 350 BaseCaviar 2024 Lexus IS 350 BaseCaviar 2024 Lexus IS 350 BaseCaviar 2024 Lexus IS 350 BaseCaviar 2024 Lexus IS 350 Base

    $48,898

    3,368 mi.
    Est. $884/mo

    Sutherland Chevrolet

    3.1
    Check Availability
    Nicholasville, KY (87 mi)
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  • Black 2018 Lexus IS 350 BaseBlack 2018 Lexus IS 350 BaseBlack 2018 Lexus IS 350 BaseBlack 2018 Lexus IS 350 BaseBlack 2018 Lexus IS 350 BaseBlack 2018 Lexus IS 350 Base

    $24,895

    $100
    114,324 mi.
    Est. $450/mo

    DriveTime of NE Nashville

    4.5
    Check Availability
    Madison, TN (93 mi)
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  • Ultra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F Sport

    $35,753

    78,217 mi.
    Est. $646/mo

    Harper Acura

    4.9
    Check Availability
    Knoxville, TN (81 mi)
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  • Gray 2025 Lexus IS 350 F-SportGray 2025 Lexus IS 350 F-SportGray 2025 Lexus IS 350 F-SportGray 2025 Lexus IS 350 F-SportGray 2025 Lexus IS 350 F-SportGray 2025 Lexus IS 350 F-Sport

    $52,998

    4,106 mi.
    Est. $958/mo

    CarMax Knoxville

    3.4
    Check Availability
    Knoxville, TN (80 mi)
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  • White 2016 Lexus IS 350 BaseWhite 2016 Lexus IS 350 BaseWhite 2016 Lexus IS 350 BaseWhite 2016 Lexus IS 350 BaseWhite 2016 Lexus IS 350 BaseWhite 2016 Lexus IS 350 Base

    $25,780

    85,568 mi.
    Est. $466/mo

    Stargate Auto Sales of Murfreesboro

    Check Availability
    Murfreesboro, TN (93 mi)
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  • $46,668

    20,713 mi.
    Est. $843/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (80 mi)
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About the Lexus IS 350

FAQs

How much does the Lexus IS 350 cost?

The Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the IS 350 is $40,903, with pricing starting at $5,495.

What is the MPG of the Lexus IS 350?

The Lexus IS 350 with traditional internal combustion engine offers up to 20 MPG city and 28 MPG highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus IS 350?

The Lexus IS 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus IS 350?

The Lexus IS 350 is available in the following trim levels:

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