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  • Iridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 BaseIridium 2022 Lexus IS 350 Base

    $37,989

    36,451 mi.
    Est. $693/mo

    VIP Auto Enterprise 2

    Check Availability
    Orlando, FL (29 mi)
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  • Ultra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F SportUltra White 2022 Lexus IS 350 F Sport

    $40,290

    51,531 mi.
    Est. $735/mo

    Coastal Hyundai

    3.9
    Check Availability
    Melbourne, FL (29 mi)
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  • 2015 Lexus IS 350 Base2015 Lexus IS 350 Base2015 Lexus IS 350 Base2015 Lexus IS 350 Base2015 Lexus IS 350 Base2015 Lexus IS 350 Base

    $12,988

    151,765 mi.
    Est. $237/mo

    Winter Park Auto Exchange

    5.0
    Check Availability
    Orlando, FL (30 mi)
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  • Liquid Platinum 2020 Lexus IS 350 BaseLiquid Platinum 2020 Lexus IS 350 BaseLiquid Platinum 2020 Lexus IS 350 BaseLiquid Platinum 2020 Lexus IS 350 BaseLiquid Platinum 2020 Lexus IS 350 BaseLiquid Platinum 2020 Lexus IS 350 Base

    $32,684

    $400
    50,674 mi.
    Est. $596/mo

    Kernersville Chrysler Dodge Jeep RAM

    4.3
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    $2,544 delivery from Kernersville, NC (531 mi)
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  • caviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Base

    $52,995

    8,583 mi.
    Est. $967/mo

    Impex Chevrolet GMC

    4.7
    Check Availability
    $625 delivery from Reidsville, NC (548 mi)
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  • Ultra White 2024 Lexus IS 350 F SPORT DesignUltra White 2024 Lexus IS 350 F SPORT DesignUltra White 2024 Lexus IS 350 F SPORT DesignUltra White 2024 Lexus IS 350 F SPORT DesignUltra White 2024 Lexus IS 350 F SPORT DesignUltra White 2024 Lexus IS 350 F SPORT Design

    $42,407

    $600
    12,591 mi.
    Est. $774/mo

    Mercedes-Benz of South Orlando

    4.1
    Check Availability
    Orlando, FL (39 mi)
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  • Iridium 2024 Lexus IS 350 F SPORTIridium 2024 Lexus IS 350 F SPORTIridium 2024 Lexus IS 350 F SPORTIridium 2024 Lexus IS 350 F SPORTIridium 2024 Lexus IS 350 F SPORTIridium 2024 Lexus IS 350 F SPORT

    $44,326

    $300
    22,909 mi.
    Est. $809/mo

    Napleton's Volkswagen of Sanford

    4.5
    Check Availability
    Sanford, FL (36 mi)
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  • INCOGNITO 2024 Lexus IS 350 F SPORT DesignINCOGNITO 2024 Lexus IS 350 F SPORT DesignINCOGNITO 2024 Lexus IS 350 F SPORT DesignINCOGNITO 2024 Lexus IS 350 F SPORT DesignINCOGNITO 2024 Lexus IS 350 F SPORT DesignINCOGNITO 2024 Lexus IS 350 F SPORT Design

    $45,233

    20,703 mi.
    Est. $825/mo

    Fountain Acura

    4.2
    Check Availability
    Oralndo, FL (37 mi)
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  • Ultra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 Base

    $38,767

    54,009 mi.
    Est. $707/mo

    Florida Preowned

    4.9
    Check Availability
    Orlando, FL (38 mi)
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  • caviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Basecaviar 2025 Lexus IS 350 Base

    $48,128

    1,376 mi.
    Est. $878/mo

    Lexus of Winter Park

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    Winter Park, FL (32 mi)
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  • Ultra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 BaseUltra White 2023 Lexus IS 350 Base

    $44,701

    23,153 mi.
    Est. $815/mo

    Lexus of Orlando

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    Orlando, FL (40 mi)
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  • Obsidian 2016 Lexus IS 350 BaseObsidian 2016 Lexus IS 350 BaseObsidian 2016 Lexus IS 350 BaseObsidian 2016 Lexus IS 350 BaseObsidian 2016 Lexus IS 350 BaseObsidian 2016 Lexus IS 350 Base

    $28,992

    $1.4K
    29,010 mi.
    Est. $529/mo

    AutoNation USA Sanford

    3.5
    Check Availability
    Sanford, FL (40 mi)
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  • ultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Baseultra white 2025 Lexus IS 350 Base

    $48,628

    911 mi.
    Est. $887/mo

    Lexus of Orlando

    Check Availability
    Orlando, FL (40 mi)
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  • Atomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 Base

    $35,375

    63,447 mi.
    Est. $645/mo

    Lexus of Winter Park

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    Winter Park, FL (32 mi)
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  • Infrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 BaseInfrared 2022 Lexus IS 350 Base

    $43,275

    32,703 mi.
    Est. $789/mo

    Lexus of Winter Park

    Check Availability
    Winter Park, FL (32 mi)
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  • Atomic Silver 2023 Lexus IS 350 BaseAtomic Silver 2023 Lexus IS 350 BaseAtomic Silver 2023 Lexus IS 350 BaseAtomic Silver 2023 Lexus IS 350 BaseAtomic Silver 2023 Lexus IS 350 BaseAtomic Silver 2023 Lexus IS 350 Base

    $42,279

    41,490 mi.
    Est. $771/mo

    Lexus of Winter Park

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    Winter Park, FL (32 mi)
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  • ultra white 2026 Lexus IS 350 Baseultra white 2026 Lexus IS 350 Baseultra white 2026 Lexus IS 350 Baseultra white 2026 Lexus IS 350 Baseultra white 2026 Lexus IS 350 Baseultra white 2026 Lexus IS 350 Base

    $50,268

    1,376 mi.
    Est. $917/mo

    Lexus of Orlando

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    Orlando, FL (40 mi)
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About the Lexus IS 350

FAQs

How much does the Lexus IS 350 cost?

The Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the IS 350 is $41,248, with pricing starting at $5,495.

What is the MPG of the Lexus IS 350?

The Lexus IS 350 with traditional internal combustion engine offers up to 20 MPG city and 28 MPG highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus IS 350?

The Lexus IS 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus IS 350?

The Lexus IS 350 is available in the following trim levels:

What model years are available for the Lexus IS 350?

Available model years for Lexus IS 350 inventory range from 2015 to 2022.

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