Skip to main content
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed
Skip to Filters
  • Eminent White Pearl 2016 Lexus RX 350 BaseEminent White Pearl 2016 Lexus RX 350 BaseEminent White Pearl 2016 Lexus RX 350 BaseEminent White Pearl 2016 Lexus RX 350 BaseEminent White Pearl 2016 Lexus RX 350 BaseEminent White Pearl 2016 Lexus RX 350 Base

    $26,610

    54,038 mi.
    Est. $485/mo

    Fred Anderson Acura

    4.8
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $35,546

    $1.3K
    44,838 mi.
    Est. $648/mo

    Escude Nissan of Greer

    4.3
    Check Availability
    Greer, SC (12 mi)
    Quick view
  • Atomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium PlusAtomic Silver 2022 Lexus RX 350 Premium Plus

    $42,995

    40,229 mi.
    Est. $784/mo

    Nodine Motor

    Check Availability
    Inman, SC (3 mi)
    Quick view
  • Iridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 PremiumIridium 2024 Lexus RX 350 Premium

    $49,767

    $1K
    19,685 mi.
    Est. $908/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Caviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT Handling

    $41,502

    $271
    42,735 mi.
    Est. $757/mo

    Fred Anderson Toyota of Greer

    3.6
    Check Availability
    Greer, SC (12 mi)
    Quick view
  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $41,767

    40,398 mi.
    Est. $762/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Nightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 LuxuryNightfall Mica 2023 Lexus RX 350 Luxury

    $56,767

    $1K
    12,236 mi.
    Est. $1,036/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Matador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT HandlingMatador Red Mica 2022 Lexus RX 350 F SPORT Handling

    $41,767

    $1.2K
    52,101 mi.
    Est. $762/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Eminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium Plus

    $53,367

    $400
    14,273 mi.
    Est. $974/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $38,367

    $400
    61,188 mi.
    Est. $700/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Iridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT DesignIridium 2025 Lexus RX 350 F SPORT Design

    $57,767

    9,632 mi.
    Est. $1,054/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Copper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium PlusCopper Crest 2023 Lexus RX 350 Premium Plus

    $47,367

    29,096 mi.
    Est. $864/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Caviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 PremiumCaviar 2023 Lexus RX 350 Premium

    $48,767

    21,778 mi.
    Est. $890/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Blue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT AppearanceBlue 2021 Lexus RX 350 F SPORT Appearance

    $32,395

    $4K
    49,257 mi.
    Est. $591/mo

    Century BMW

    4.8
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Eminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT HandlingEminent White Pearl 2023 Lexus RX 350 F SPORT Handling

    $48,500

    $1.5K
    42,987 mi.
    Est. $885/mo

    Fred Anderson Kia of Greer

    4.4
    Check Availability
    Greer, SC (12 mi)
    Quick view
  • Cerulean Blue Metallic 2011 Lexus RX 350 BaseCerulean Blue Metallic 2011 Lexus RX 350 BaseCerulean Blue Metallic 2011 Lexus RX 350 BaseCerulean Blue Metallic 2011 Lexus RX 350 BaseCerulean Blue Metallic 2011 Lexus RX 350 BaseCerulean Blue Metallic 2011 Lexus RX 350 Base

    $11,499

    136,951 mi.
    Est. $210/mo

    VP Auto

    Check Availability
    Greenville, SC (30 mi)
    Quick view
  • Silver 2019 Lexus RX 350Silver 2019 Lexus RX 350Silver 2019 Lexus RX 350Silver 2019 Lexus RX 350Silver 2019 Lexus RX 350Silver 2019 Lexus RX 350

    $31,998

    61,932 mi.
    Est. $584/mo

    CarMax Greenville

    2.1
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Nebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium PlusNebula Gray Pearl 2023 Lexus RX 350 Premium Plus

    $45,767

    $600
    45,788 mi.
    Est. $835/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Gold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 BaseGold 2008 Lexus RX 350 Base

    $9,995

    179,160 mi.
    Est. $182/mo

    Auto-Fleet

    Check Availability
    Spartanburg, SC (10 mi)
    Quick view
  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $46,767

    $601
    37,738 mi.
    Est. $853/mo

    Lexus of Greenville

    3.9
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Caviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 Premium

    $52,187

    $188
    7,600 mi.
    Est. $952/mo

    Fred Anderson Toyota of Greer

    3.6
    Check Availability
    Greer, SC (12 mi)
    Quick view
  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $31,998

    $1K
    67,490 mi.
    Est. $584/mo

    CarMax Greenville

    2.1
    Check Availability
    Greenville, SC (24 mi)
    Quick view
  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $36,998

    42,879 mi.
    Est. $675/mo

    CarMax Newport News

    Check Availability
    $249 delivery to Greenville, SC (24 mi)
    Quick view
  • Matador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 LuxuryMatador Red Mica 2024 Lexus RX 350 Luxury

    $53,450

    26,730 mi.
    Est. $975/mo

    Impex Auto Sales

    4.8
    Check Availability
    $200 delivery from Greensboro, NC (141 mi)
    Quick view

Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $62,980
2025 Lexus RX 350 $57,472 1 Good deal
2023 Lexus RX 350 $50,567 2 Good deals

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $34,974, with pricing starting at $3,900.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2008 to 2026.

Skip to Listings
Best match Lowest price Highest price Lowest mileage Highest mileage Nearest location Best deal Newest year Oldest year Newest listed Oldest listed

Used Lexus RX 350 by price

Similar Cars

Compare the Lexus RX 350

Used Lexus RX 350 by city