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  • SILVER 2021 Lexus IS 350 BaseSILVER 2021 Lexus IS 350 BaseSILVER 2021 Lexus IS 350 BaseSILVER 2021 Lexus IS 350 BaseSILVER 2021 Lexus IS 350 BaseSILVER 2021 Lexus IS 350 Base

    $33,920

    93,755 mi.
    Est. $625/mo

    Used Imports Auto

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    Lawrenceville, GA (18 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $37,618

    $200
    59,547 mi.
    Est. $693/mo

    Hennessy Lexus Gwinnett

    4.1
    Check Availability
    Duluth, GA (17 mi)
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  • Infrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 Base

    $44,018

    25,589 mi.
    Est. $810/mo

    Hennessy Lexus Gwinnett

    4.1
    Check Availability
    Duluth, GA (17 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $35,985

    63,161 mi.
    Est. $663/mo

    Gravity Autos Sandy Springs

    3.3
    Check Availability
    Sandy Springs, GA (14 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $39,997

    $993
    43,461 mi.
    Est. $736/mo

    Gravity Autos Duluth

    1.3
    Check Availability
    Duluth, GA (17 mi)
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  • Atomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 Base

    $33,920

    95,999 mi.
    Est. $625/mo

    Used Imports Auto

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    Lawrenceville, GA (18 mi)
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  • White 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-Sport

    $33,998

    68,507 mi.
    Est. $626/mo

    CarMax Ft. Lauderdale

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    $149 delivery to Norcross, GA (14 mi)
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  • Red 2021 Lexus IS 350 F-SportRed 2021 Lexus IS 350 F-SportRed 2021 Lexus IS 350 F-SportRed 2021 Lexus IS 350 F-SportRed 2021 Lexus IS 350 F-SportRed 2021 Lexus IS 350 F-Sport

    $39,998

    $2K
    44,976 mi.
    Est. $736/mo

    CarMax Costa Mesa

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    $1,399 delivery to Norcross, GA (14 mi)
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  • Silver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 Base

    $38,698

    62,059 mi.
    Est. $713/mo

    Lexus of Birmingham

    4.9
    Check Availability
    Irondale, AL (138 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $34,698

    70,830 mi.
    Est. $639/mo

    Lexus of Birmingham

    4.9
    Check Availability
    Irondale, AL (138 mi)
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  • White 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-Sport

    $38,998

    44,352 mi.
    Est. $718/mo

    CarMax Murfreesboro

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    Murfreesboro, TN (191 mi)
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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $29,950

    $1.5K
    106,906 mi.
    Est. $551/mo

    Auto Union Inc.

    Check Availability
    Smyrna, TN (197 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $54,999
2023 Lexus IS 350 $44,729 16 Good deals

About the 2021 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus IS 350
FAQs

How much does the 2021 Lexus IS 350 cost?

The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $37,822, with pricing starting at $29,950.

What is the MPG of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2021 Lexus IS 350 reliable?

The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.

Is the 2021 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $42,950 Starting at $44,950
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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