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  • Iridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F Sport

    $32,991

    61,623 mi.
    Est. $602/mo

    Miami Lakes Automall - Chevrolet Kia Dodge Chrysler Jeep Ram Mitsubishi

    3.5
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    Hialeah, FL (12 mi)

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  • Silver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 Base

    $36,900

    37,264 mi.
    Est. $673/mo

    Ocean Mazda

    4.7
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    Miami, FL (10 mi)
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  • Iridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F Sport

    $32,991

    61,623 mi.
    Est. $602/mo

    NowCar - Delivery from Miami, Fl for Orlando Fl

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    Miami Lakes, FL (12 mi)
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  • Blue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 Base

    $32,800

    46,317 mi.
    Est. $598/mo

    Elite Auto Auctions

    3.4
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    Hollywood, FL (17 mi)
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  • Gray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-Sport

    $40,998

    35,015 mi.
    Est. $748/mo

    CarMax Independence Boulevard

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    $349 delivery to Doral, FL (10 mi)
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  • White 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-Sport

    $38,998

    $3K
    44,330 mi.
    Est. $711/mo

    CarMax Huntsville

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    $799 delivery to Doral, FL (10 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $39,350

    $249
    50,805 mi.
    Est. $718/mo

    Germain Lexus of Naples

    4.9
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    Naples, FL (106 mi)
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  • Grecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 Base

    $38,083

    46,905 mi.
    Est. $695/mo

    BMW of Pompano Beach

    4.7
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    Pompano Beach, FL (32 mi)
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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $29,489

    111,407 mi.
    Est. $538/mo

    Lexus of Palm Beach

    4.8
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    West Palm Beach, FL (64 mi)
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  • Blue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 BaseBlue 2021 Lexus IS 350 Base

    $41,720

    44,929 mi.
    Est. $761/mo

    Group 1 Chevrolet Estero Bay

    4.4
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    Estero, FL (108 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $52,375 1 Good deal
2025 Lexus IS 350 $44,914 5 Great deals
2024 Lexus IS 350 $42,736 5 Great deals
2023 Lexus IS 350 $42,089 6 Great deals

About the 2021 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus IS 350
FAQs

How much does the 2021 Lexus IS 350 cost?

The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $37,943, with pricing starting at $25,992.

What is the MPG of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2021 Lexus IS 350 reliable?

The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.

Is the 2021 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $42,950 Starting at $44,950
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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