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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $37,989

    31,166 mi.
    Est. $666/mo

    DCH Kay Honda

    4.8
    Check Availability
    Eatontown, NJ (29 mi)
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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $36,495

    76,547 mi.
    Est. $640/mo

    MotorHub Inc.

    Check Availability
    Inwood, NY (11 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $36,995

    $400
    60,026 mi.
    Est. $649/mo

    Crazy Cars

    3.8
    Check Availability
    Hillside, NJ (17 mi)
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  • White 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-SportWhite 2021 Lexus IS 350 F-Sport

    $32,998

    90,102 mi.
    Est. $579/mo

    CarMax Des Moines

    4.0
    Check Availability
    $699 delivery to East Meadow, NY (20 mi)
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  • Gray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-Sport

    $34,998

    61,925 mi.
    Est. $614/mo

    CarMax Tampa

    4.0
    Check Availability
    $1,099 delivery to East Meadow, NY (20 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $36,945

    55,193 mi.
    Est. $648/mo

    Loehmann-Blasius Chevrolet

    4.0
    Check Availability
    Waterbury, CT (77 mi)
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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $39,707

    37,016 mi.
    Est. $696/mo

    Pine Belt Chevy of Lakewood

    4.9
    Check Availability
    Lakewood, NJ (44 mi)
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  • Ultra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 BaseUltra White 2021 Lexus IS 350 Base

    $41,448

    $550
    42,856 mi.
    Est. $727/mo

    Dean Carter Chevrolet

    4.2
    Check Availability
    Brodheadsville, PA (80 mi)
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  • Atomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 BaseAtomic Silver 2021 Lexus IS 350 Base

    $30,500

    103,703 mi.
    Est. $535/mo

    AutoProved

    3.5
    Check Availability
    Allentown, PA (80 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $55,546
2024 Lexus IS 350 $47,342 7 Good deals
2023 Lexus IS 350 $42,964 8 Great deals

About the 2021 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus IS 350
FAQs

How much does the 2021 Lexus IS 350 cost?

The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $38,321, with pricing starting at $29,950.

What is the MPG of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2021 Lexus IS 350 reliable?

The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.

Is the 2021 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $42,950 Starting at $44,950
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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