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  • Silver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 Base

    $36,222

    48,255 mi.
    Est. $672/mo

    F H Dailey Chevrolet

    4.2
    Check Availability
    San Leandro, CA (12 mi)
    Quick view
  • Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350Silver 2022 Lexus RX 350

    $39,998

    $1K
    27,304 mi.
    Est. $742/mo

    CarMax Serramonte

    4.2
    Check Availability
    Colma, CA (27 mi)
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  • Gray 2022 Lexus RX 350 F-SportGray 2022 Lexus RX 350 F-SportGray 2022 Lexus RX 350 F-SportGray 2022 Lexus RX 350 F-SportGray 2022 Lexus RX 350 F-SportGray 2022 Lexus RX 350 F-Sport

    $40,998

    52,565 mi.
    Est. $760/mo

    CarMax Norco

    4.5
    Check Availability
    $99 delivery to Pleasanton, CA (12 mi)
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  • Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350

    $37,998

    28,452 mi.
    Est. $705/mo

    CarMax Oceanside

    4.2
    Check Availability
    $149 delivery to Pleasanton, CA (12 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $37,600

    $200
    80,493 mi.
    Est. $697/mo

    United Imports

    Check Availability
    San Jose, CA (35 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $38,497

    59,726 mi.
    Est. $714/mo

    Ineos Grenadier Marin

    Check Availability
    San Rafael, CA (31 mi)
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  • Gray Pearl 2022 Lexus RX 350 BaseGray Pearl 2022 Lexus RX 350 BaseGray Pearl 2022 Lexus RX 350 BaseGray Pearl 2022 Lexus RX 350 BaseGray Pearl 2022 Lexus RX 350 BaseGray Pearl 2022 Lexus RX 350 Base

    $30,495

    $500
    85,493 mi.
    Est. $565/mo

    Jimmy Vasser Toyota of Napa

    4.4
    Check Availability
    Napa, CA (37 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $38,498

    61,212 mi.
    Est. $714/mo

    Capitol Nissan

    3.8
    Check Availability
    San Jose, CA (38 mi)
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  • Mica 2022 Lexus RX 350 F SPORT Handling

    $45,438

    31,366 mi.
    Est. $842/mo

    Mercedes-Benz of Fairfield

    4.7
    Check Availability
    Fairfield, CA (30 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $62,071

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,077, with pricing starting at $26,995.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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