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  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $39,488

    49,435 mi.
    Est. $720/mo

    Bomnin Chevrolet Dadeland

    4.8
    Miami, FL (17 mi)
    Check Availability

  • White Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 Base

    $35,439

    $1.1K
    59,532 mi.
    Est. $646/mo

    Miami Lakes Automall - Chevrolet Kia Dodge Chrysler Jeep Ram Mitsubishi

    3.5
    Hialeah, FL (11 mi)
    Check Availability

  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $39,488

    49,435 mi.
    Est. $720/mo

    Bomnin Chevrolet Dadeland

    4.8
    Miami, FL (17 mi)
    Check Availability

  • Matador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT Appearance

    $33,998

    57,839 mi.
    Est. $620/mo

    Carvix of Miami

    5.0
    Miami, FL (8 mi)
    Check Availability
  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $36,988

    $500
    43,595 mi.
    Est. $675/mo

    Bomnin Chevrolet West Kendall

    4.9
    Miami, FL (24 mi)
    Check Availability
  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $41,697

    $500
    42,491 mi.
    Est. $761/mo

    HGreg.com Lux

    4.3
    Pompano Beach, FL (28 mi)
    Check Availability
  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $36,750

    45,960 mi.
    Est. $670/mo

    BMW/MINI of South Miami

    4.9
    Miami, FL (23 mi)
    Check Availability
  • White Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 Base

    $30,515

    $1K
    88,814 mi.
    Est. $557/mo

    Lexus of Kendall

    2.7
    Miami, FL (19 mi)
    Check Availability
  • Matador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT AppearanceMatador Red Mica 2022 Lexus RX 350 F SPORT Appearance

    $33,998

    57,839 mi.
    Est. $620/mo

    Carvix of Miami

    5.0
    Miami, FL (8 mi)
    Check Availability

  • Silver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 Base

    $43,491

    35,000 mi.
    Est. $793/mo

    Lexus of Kendall

    2.7
    Miami, FL (19 mi)
    Check Availability
  • $39,609

    41,102 mi.
    Est. $723/mo

    Audi Coral Springs

    4.8
    Coral Springs, FL (29 mi)
    Check Availability
  • White 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 L

    $27,998

    123,748 mi.
    Est. $511/mo

    CarMax Melbourne

    4.9
    $149 delivery to Miami Lakes, FL (11 mi)
    Check Availability
  • White 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 L

    $42,998

    $2K
    49,317 mi.
    Est. $784/mo

    CarMax South Boulevard

    4.9
    $499 delivery to Miami Lakes, FL (11 mi)
    Check Availability
  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $40,843

    $1.9K
    32,205 mi.
    Est. $745/mo

    Schumacher Chrysler Dodge Jeep Ram of Delray

    4.6
    DELRAY BEACH, FL (39 mi)
    Check Availability
  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $36,553

    41,222 mi.
    Est. $667/mo

    Kia Delray

    4.4
    Delray Beach, FL (39 mi)
    Check Availability
  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $37,744

    $238
    35,505 mi.
    Est. $689/mo

    Lexus of Palm Beach

    4.8
    West Palm Beach, FL (57 mi)
    Check Availability

Lexus RX 350 prices by year

Model year Average price Deals
2027 Lexus RX 350 $63,910
2026 Lexus RX 350 $60,519 2 Good deals
2025 Lexus RX 350 $50,629 11 Good deals
2024 Lexus RX 350 $46,721 11 Great deals
2023 Lexus RX 350 $43,029 14 Good deals
2017 Lexus RX 350 $24,317 6 Great deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $38,122, with pricing starting at $25,220.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

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