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  • 0085 Eminent Wh 2022 Lexus RX 350 Base

    $45,950

    31,653 mi.
    Est. $784/mo

    Wilkie Lexus

    4.9
    Check Availability
    Haverford, PA (12 mi)

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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $35,994

    30,446 mi.
    Est. $614/mo

    Automotive Avenues Sewell

    4.9
    Check Availability
    Washington Township, NJ (17 mi)

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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $42,990

    41,890 mi.
    Est. $734/mo

    Porter Chevrolet

    4.7
    Check Availability
    Newark, DE (23 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $40,872

    36,438 mi.
    Est. $698/mo

    AutoLenders Voorhees

    4.9
    Check Availability
    Voorhees, NJ (25 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $43,000

    $247
    36,813 mi.
    Est. $734/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (13 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $39,444

    46,318 mi.
    Est. $673/mo

    J. L. Freed Honda

    4.3
    Check Availability
    Montgomeryville, PA (28 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $44,640

    40,293 mi.
    Est. $762/mo

    AutoLenders Voorhees

    4.9
    Check Availability
    Voorhees, NJ (25 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $36,000

    88,718 mi.
    Est. $615/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (13 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $39,790

    56,234 mi.
    Est. $679/mo

    Faulkner Toyota Trevose

    4.7
    Check Availability
    Trevose, PA (29 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $43,219

    $1.7K
    39,875 mi.
    Est. $738/mo

    Ardmore Toyota

    4.7
    Check Availability
    Ardmore, PA (11 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $44,690

    40,203 mi.
    Est. $763/mo

    AutoLenders Voorhees

    4.9
    Check Availability
    Voorhees, NJ (25 mi)
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  • Red 2022 Lexus RX 350 Base

    Not Priced

    33,562 mi.
    Est. $0/mo

    Lexus of Cherry Hill

    4.8
    Check Availability
    Mount Laurel, NJ (24 mi)
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  • White 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT Handling

    $36,998

    86,727 mi.
    Est. $632/mo

    CarMax Greenville NC

    5.0
    Check Availability
    $149 delivery to King of Prussia, PA (15 mi)
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  • Silver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 L

    $39,998

    46,268 mi.
    Est. $683/mo

    CarMax Charlottesville

    Check Availability
    $149 delivery to King of Prussia, PA (15 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $38,938

    45,558 mi.
    Est. $665/mo

    Pine Belt Mazda

    4.9
    Check Availability
    Lakewood, NJ (67 mi)
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  • Red 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 Base

    $34,999

    38,564 mi.
    Est. $597/mo

    G-Motors of Old Bridge

    4.4
    Check Availability
    Old Bridge, NJ (71 mi)
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  • Mica 2022 Lexus RX 350 RX 350Mica 2022 Lexus RX 350 RX 350Mica 2022 Lexus RX 350 RX 350Mica 2022 Lexus RX 350 RX 350Mica 2022 Lexus RX 350 RX 350Mica 2022 Lexus RX 350 RX 350

    $38,252

    $1.1K
    70,897 mi.
    Est. $653/mo

    Piazza Acura / Honda of Reading

    4.8
    Check Availability
    Reading, PA (43 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 PremiumEminent White Pearl 2022 Lexus RX 350 PremiumEminent White Pearl 2022 Lexus RX 350 PremiumEminent White Pearl 2022 Lexus RX 350 PremiumEminent White Pearl 2022 Lexus RX 350 PremiumEminent White Pearl 2022 Lexus RX 350 Premium

    $39,594

    44,048 mi.
    Est. $676/mo

    Automotive Avenues

    4.8
    Check Availability
    Wall Township, NJ (72 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $64,216 1 Good deal
2024 Lexus RX 350 $51,403 8 Great deals
2023 Lexus RX 350 $47,943 6 Great deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,471, with pricing starting at $27,447.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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