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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $46,500

    46,757 mi.
    Est. $840/mo

    Beaver Toyota Cumming

    4.7
    Check Availability
    Cumming, GA (19 mi)

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  • Grecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT AppearanceGrecian Water 2022 Lexus RX 350 F SPORT Appearance

    $34,920

    71,049 mi.
    Est. $631/mo

    ALM Roswell

    4.4
    Check Availability
    Roswell, GA (27 mi)

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  • Eminent White Pearl 2022 Lexus RX 350 RX 350Eminent White Pearl 2022 Lexus RX 350 RX 350Eminent White Pearl 2022 Lexus RX 350 RX 350Eminent White Pearl 2022 Lexus RX 350 RX 350Eminent White Pearl 2022 Lexus RX 350 RX 350Eminent White Pearl 2022 Lexus RX 350 RX 350

    $36,125

    111,161 mi.
    Est. $653/mo

    Rick Hendrick Chevrolet of Duluth

    4.9
    Check Availability
    Duluth, GA (14 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $44,890

    $100
    46,750 mi.
    Est. $811/mo

    Hennessy Lexus Gwinnett

    4.1
    Check Availability
    Duluth, GA (15 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $43,677

    $100
    25,329 mi.
    Est. $789/mo

    Gravity Autos Duluth

    1.3
    Check Availability
    Duluth, GA (14 mi)
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  • Gray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT HandlingGray Pearl 2022 Lexus RX 350 F SPORT Handling

    $39,990

    $800
    77,430 mi.
    Est. $723/mo

    Hennessy Lexus Gwinnett

    4.1
    Check Availability
    Duluth, GA (15 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $41,695

    $200
    69,139 mi.
    Est. $754/mo

    Gravity Autos Sandy Springs

    3.6
    Check Availability
    Sandy Springs, GA (28 mi)
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  • Caviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 Premium

    $43,990

    31,476 mi.
    Est. $795/mo

    Hennessy Lexus of Atlanta

    3.4
    Check Availability
    Atlanta, GA (24 mi)
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  • Matador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 BaseMatador Red Mica 2022 Lexus RX 350 Base

    $44,990

    $900
    48,150 mi.
    Est. $813/mo

    Hennessy Lexus Gwinnett

    4.1
    Check Availability
    Duluth, GA (15 mi)
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  • Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350Black 2022 Lexus RX 350

    $37,998

    $1K
    48,610 mi.
    Est. $687/mo

    CarMax Norcross

    2.5
    Check Availability
    Norcross, GA (17 mi)
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  • Atomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 PremiumAtomic Silver 2022 Lexus RX 350 Premium

    $42,990

    $500
    45,385 mi.
    Est. $777/mo

    Hennessy Lexus of Atlanta

    3.4
    Check Availability
    Atlanta, GA (24 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $44,990

    43,278 mi.
    Est. $813/mo

    Hennessy Lexus Gwinnett

    4.1
    Check Availability
    Duluth, GA (15 mi)
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  • Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350

    $41,998

    31,093 mi.
    Est. $759/mo

    CarMax Norcross

    2.5
    Check Availability
    Norcross, GA (17 mi)
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  • Caviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 Premium

    $42,990

    59,509 mi.
    Est. $777/mo

    Hennessy Lexus of Atlanta

    3.4
    Check Availability
    Atlanta, GA (24 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $33,995

    $1K
    55,335 mi.
    Est. $614/mo

    Auto Buying Service

    4.0
    Check Availability
    $526 delivery from Fairfax, VA (501 mi)
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  • Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350Gray 2022 Lexus RX 350

    $46,998

    15,292 mi.
    Est. $849/mo

    CarMax Greenwood

    Check Availability
    $349 delivery to Buford, GA (10 mi)
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  • Black 2022 Lexus RX 350 LBlack 2022 Lexus RX 350 LBlack 2022 Lexus RX 350 LBlack 2022 Lexus RX 350 LBlack 2022 Lexus RX 350 LBlack 2022 Lexus RX 350 L

    $42,998

    34,349 mi.
    Est. $777/mo

    CarMax Town Center

    Check Availability
    Kennesaw, GA (40 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $46,990

    52,257 mi.
    Est. $849/mo

    Butler Lexus of South Atlanta

    4.7
    Check Availability
    Union City, GA (47 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $31,720

    $200
    92,587 mi.
    Est. $573/mo

    ALM Mazda South

    4.3
    Check Availability
    Morrow, GA (40 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $34,991

    $1K
    88,810 mi.
    Est. $632/mo

    INFINITI of South Atlanta

    3.2
    Check Availability
    Union City, GA (47 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $44,894

    45,785 mi.
    Est. $811/mo

    Butler Lexus of South Atlanta

    4.7
    Check Availability
    Union City, GA (47 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $44,620

    54,305 mi.
    Est. $806/mo

    Nalley Lexus Galleria

    4.8
    Check Availability
    Smyrna, GA (35 mi)
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  • $43,794

    42,225 mi.
    Est. $791/mo

    Butler Lexus of South Atlanta

    4.7
    Check Availability
    Union City, GA (47 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,535
2025 Lexus RX 350 $53,200 7 Good deals
2024 Lexus RX 350 $51,128 17 Good deals
2023 Lexus RX 350 $48,640 9 Great deals
2017 Lexus RX 350 $25,384 5 Great deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,008, with pricing starting at $27,790.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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