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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $36,195

    30,446 mi.
    Est. $658/mo

    Automotive Avenues Sewell

    5.0
    Check Availability
    Washington Township, NJ (12 mi)

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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $44,449

    24,113 mi.
    Est. $808/mo

    Piazza Acura of West Chester

    4.8
    Check Availability
    West Chester, PA (27 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $47,443

    $356
    17,875 mi.
    Est. $862/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (30 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $41,798

    $200
    21,167 mi.
    Est. $760/mo

    Hamilton Honda

    4.1
    Check Availability
    Hamilton, NJ (30 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $39,895

    46,312 mi.
    Est. $725/mo

    J. L. Freed Honda

    4.3
    Check Availability
    Montgomeryville, PA (26 mi)
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  • Caviar - 223 2022 Lexus RX 350 BaseCaviar - 223 2022 Lexus RX 350 BaseCaviar - 223 2022 Lexus RX 350 BaseCaviar - 223 2022 Lexus RX 350 BaseCaviar - 223 2022 Lexus RX 350 BaseCaviar - 223 2022 Lexus RX 350 Base

    $45,499

    20,166 mi.
    Est. $827/mo

    Lexus of Cherry Hill

    4.8
    Check Availability
    Mount Laurel, NJ (7 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $43,995

    40,203 mi.
    Est. $800/mo

    AutoLenders Voorhees

    4.9
    Check Availability
    Voorhees, NJ (10 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $43,247

    $753
    36,813 mi.
    Est. $786/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (30 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $35,000

    $1.4K
    80,070 mi.
    Est. $636/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (30 mi)
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  • $36,000

    88,718 mi.
    Est. $654/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (30 mi)
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  • $41,000

    46,589 mi.
    Est. $745/mo

    Lexus of Wilmington

    4.9
    Check Availability
    Wilmington, DE (30 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $33,995

    $1K
    55,335 mi.
    Est. $618/mo

    Auto Buying Service

    4.0
    Check Availability
    $300 delivery from Fairfax, VA (137 mi)
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  • White 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 LWhite 2022 Lexus RX 350 L

    $42,998

    30,613 mi.
    Est. $782/mo

    CarMax Mechanicsburg

    Check Availability
    Free delivery to Maple Shade Township, NJ (5 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $36,995

    $1K
    55,163 mi.
    Est. $673/mo

    Auto Hub

    4.6
    Check Availability
    North Brunswick, NJ (46 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $40,178

    36,438 mi.
    Est. $730/mo

    AutoLenders Lakewood

    5.0
    Check Availability
    Lakewood, NJ (49 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT AppearanceNebula Gray Pearl 2022 Lexus RX 350 F SPORT Appearance

    $38,941

    45,558 mi.
    Est. $708/mo

    Pine Belt Mazda

    4.9
    Check Availability
    Lakewood, NJ (49 mi)
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  • White Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 BaseWhite Pearl 2022 Lexus RX 350 Base

    $42,752

    27,269 mi.
    Est. $777/mo

    Fred Beans Hyundai of Flemington

    Check Availability
    Flemington, NJ (41 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $44,658

    19,378 mi.
    Est. $812/mo

    Hertrich Acura

    3.7
    Check Availability
    New Castle, DE (34 mi)
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  • Caviar 2022 Lexus RX 350 Base

    $43,990

    22,648 mi.
    Est. $800/mo

    BMW of Freehold

    4.8
    Check Availability
    Freehold, NJ (48 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $65,296
2024 Lexus RX 350 $50,661 12 Good deals
2023 Lexus RX 350 $47,055 26 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $40,906, with pricing starting at $26,995.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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