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  • Ultra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F Sport

    $35,706

    85,766 mi.
    Est. $622/mo

    Toyota of Plano

    4.7
    Plano, TX (16 mi)
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  • Infrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F Sport

    $37,199

    59,938 mi.
    Est. $649/mo

    Reliable Chevrolet

    4.4
    Richardson, TX (26 mi)
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  • Grecian Water 2021 Lexus IS 350 F SportGrecian Water 2021 Lexus IS 350 F SportGrecian Water 2021 Lexus IS 350 F SportGrecian Water 2021 Lexus IS 350 F SportGrecian Water 2021 Lexus IS 350 F SportGrecian Water 2021 Lexus IS 350 F Sport

    $42,202

    33,835 mi.
    Est. $736/mo

    Tom Clark Chevrolet

    Denton, TX (7 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F Sport

    $37,215

    60,769 mi.
    Est. $649/mo

    Grapevine Ford Lincoln

    4.4
    Grapevine, TX (16 mi)
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  • Ultra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F SportUltra White 2021 Lexus IS 350 F Sport

    $40,724

    $5.2K
    30,077 mi.
    Est. $710/mo

    Prosper Ford

    4.6
    Prosper, TX (19 mi)
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  • Caviar 2021 Lexus IS 350 F SportCaviar 2021 Lexus IS 350 F SportCaviar 2021 Lexus IS 350 F SportCaviar 2021 Lexus IS 350 F SportCaviar 2021 Lexus IS 350 F SportCaviar 2021 Lexus IS 350 F Sport

    $39,125

    $700
    39,019 mi.
    Est. $682/mo

    Sewell Lexus of Dallas

    3.3
    Dallas, TX (27 mi)
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  • Silver 2021 Lexus IS 350 350 F SPORTSilver 2021 Lexus IS 350 350 F SPORTSilver 2021 Lexus IS 350 350 F SPORTSilver 2021 Lexus IS 350 350 F SPORTSilver 2021 Lexus IS 350 350 F SPORTSilver 2021 Lexus IS 350 350 F SPORT

    $34,488

    78,223 mi.
    Est. $601/mo

    Alfa Romeo of Plano

    2.9
    Plano, TX (21 mi)
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  • White 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F SportWhite 2021 Lexus IS 350 F Sport

    $36,995

    68,817 mi.
    Est. $645/mo

    Autos of Plano

    3.1
    Plano, TX (26 mi)
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  • Iridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F SportIridium 2021 Lexus IS 350 F Sport

    $34,913

    94,447 mi.
    Est. $609/mo

    Sewell Lexus of Dallas

    3.3
    Dallas, TX (27 mi)
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  • Infrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F SportInfrared 2021 Lexus IS 350 F Sport

    $39,971

    $2.1K
    48,778 mi.
    Est. $697/mo

    Mercedes-Benz of Buckhead

    4.5
    $1,102 delivery from Atlanta, GA (735 mi)
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  • Gray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-SportGray 2021 Lexus IS 350 F-Sport

    $39,998

    46,110 mi.
    Est. $697/mo

    CarMax Knoxville

    4.4
    $899 delivery to Denton, TX (2 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F SportCloudburst Gray 2021 Lexus IS 350 F Sport

    $36,997

    74,474 mi.
    Est. $645/mo

    Northside Lexus

    4.9
    Spring, TX (232 mi)
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  • Not Priced

    82,309 mi.
    Est. $0/mo

    Autos of Texas

    TYLER, TX (118 mi)
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  • Infrared 2021 Lexus IS 350 F Sport

    $36,000

    21,091 mi.
    Est. $628/mo

    AutoSavvy Houston

    Houston, TX (242 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $56,140 1 Good deal
2025 Lexus IS 350 $47,342 8 Good deals
2024 Lexus IS 350 $42,232 6 Good deals
2023 Lexus IS 350 $45,760 6 Great deals
2022 Lexus IS 350 $41,741 8 Good deals

About the 2021 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus IS 350
FAQs

How much does the 2021 Lexus IS 350 cost?

The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $38,347, with pricing starting at $29,690.

What is the MPG of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 compares to and/or competes against the following vehicles:


  • Mitsubishi Lancer
  • Lexus IS 500
  • Lexus IS 300
  • Genesis G70
  • BMW M340
  • Acura TLX

Is the 2021 Lexus IS 350 reliable?

The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.

Is the 2021 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $42,950 Starting at $44,950
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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