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  • Nebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 BaseNebula Gray Pearl 2021 Lexus RX 350 Base

    $30,988

    102,209 mi.
    Est. $572/mo

    Park Place Lexus Grapevine

    4.7
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    Grapevine, TX (25 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $42,220

    8,511 mi.
    Est. $779/mo

    Sewell Lexus of Fort Worth

    Check Availability
    Fort Worth, TX (18 mi)
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  • Ultra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT HandlingUltra White 2021 Lexus RX 350 F SPORT Handling

    $34,290

    $1.2K
    82,617 mi.
    Est. $633/mo

    David McDavid Honda Irving

    4.6
    Check Availability
    Irving, TX (21 mi)
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  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $36,975

    64,757 mi.
    Est. $682/mo

    Park Place Lexus Grapevine

    4.7
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    Grapevine, TX (25 mi)
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  • White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350

    $44,998

    15,140 mi.
    Est. $830/mo

    CarMax Texas Stadium (Irving)

    4.2
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    Irving, TX (24 mi)
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  • Ultra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT Appearance

    $43,975

    39,246 mi.
    Est. $812/mo

    Park Place Lexus Grapevine

    4.7
    Check Availability
    Grapevine, TX (25 mi)
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  • Gold 2021 Lexus RX 350Gold 2021 Lexus RX 350Gold 2021 Lexus RX 350Gold 2021 Lexus RX 350Gold 2021 Lexus RX 350Gold 2021 Lexus RX 350

    $37,998

    $1K
    53,253 mi.
    Est. $701/mo

    CarMax Texas Stadium (Irving)

    4.2
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    Irving, TX (24 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $46,713

    42,397 mi.
    Est. $862/mo

    Sewell Lexus of Dallas

    3.4
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    Dallas, TX (26 mi)
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  • Moonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 BaseMoonbeam Beige Metallic 2021 Lexus RX 350 Base

    $43,216

    19,292 mi.
    Est. $798/mo

    Hiley Hyundai of Fort Worth

    4.9
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    Fort Worth, TX (23 mi)
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  • $35,213

    84,517 mi.
    Est. $650/mo

    Sewell Lexus of Dallas

    3.4
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    Dallas, TX (26 mi)
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  • Silver 2021 Lexus RX 350 F-SPORT HandlingSilver 2021 Lexus RX 350 F-SPORT HandlingSilver 2021 Lexus RX 350 F-SPORT HandlingSilver 2021 Lexus RX 350 F-SPORT HandlingSilver 2021 Lexus RX 350 F-SPORT HandlingSilver 2021 Lexus RX 350 F-SPORT Handling

    $33,998

    87,861 mi.
    Est. $627/mo

    CarMax Tyler

    4.5
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    Free delivery to Fort Worth, TX (14 mi)
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  • White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350

    $40,998

    24,702 mi.
    Est. $757/mo

    CarMax Louisville

    3.9
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    $449 delivery to Fort Worth, TX (14 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $34,217

    72,495 mi.
    Est. $631/mo

    Van Hyundai

    4.2
    Check Availability
    Carrollton, TX (31 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $33,936

    78,072 mi.
    Est. $626/mo

    Shottenkirk Toyota of Weatherford

    4.8
    Check Availability
    Weatherford, TX (35 mi)
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  • Silver 2021 Lexus RX 350Silver 2021 Lexus RX 350Silver 2021 Lexus RX 350Silver 2021 Lexus RX 350Silver 2021 Lexus RX 350Silver 2021 Lexus RX 350

    $36,998

    52,575 mi.
    Est. $683/mo

    CarMax Denton

    4.8
    Check Availability
    Denton, TX (42 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $65,288 1 Good deal
2025 Lexus RX 350 $58,084 6 Great deals
2024 Lexus RX 350 $54,537 31 Good deals
2023 Lexus RX 350 $51,037 9 Great deals
2015 Lexus RX 350 $19,902 6 Great deals

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $36,731, with pricing starting at $22,500.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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