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  • Matador Red Mica 2021 Lexus RX 350 Base

    $35,077

    58,617 mi.
    Est. $656/mo

    Lexus of Cerritos

    4.8
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    Cerritos, CA (16 mi)

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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $32,888

    66,994 mi.
    Est. $615/mo

    Longo Lexus

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    El Monte, CA (25 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $34,394

    62,847 mi.
    Est. $644/mo

    Audi Long Beach

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    Signal Hill, CA (13 mi)
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  • Caviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT HandlingCaviar 2021 Lexus RX 350 F SPORT Handling

    $44,208

    24,710 mi.
    Est. $827/mo

    Lexus Santa Monica

    4.0
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    Santa Monica, CA (13 mi)
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  • Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350Black 2021 Lexus RX 350 RX 350

    $33,998

    55,625 mi.
    Est. $636/mo

    CarMax Canoga Park

    4.6
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    Canoga Park, CA (28 mi)
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  • Ultra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT AppearanceUltra White 2021 Lexus RX 350 F SPORT Appearance

    $42,988

    $5K
    40,990 mi.
    Est. $804/mo

    Lexus of Glendale

    4.8
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    Glendale, CA (20 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $32,488

    $220
    45,984 mi.
    Est. $608/mo

    Wondries Toyota

    4.6
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    Alhambra, CA (21 mi)
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  • Nebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 Premium

    $40,995

    33,849 mi.
    Est. $767/mo

    STG Auto Group of Bellflower

    2.5
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    Bellflower, CA (13 mi)
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  • White 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 LWhite 2021 Lexus RX 350 L

    $36,998

    45,338 mi.
    Est. $692/mo

    CarMax LAX

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    Inglewood, CA (6 mi)
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  • Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350Gray 2021 Lexus RX 350

    $35,998

    40,698 mi.
    Est. $674/mo

    CarMax Costa Mesa

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    Costa Mesa, CA (30 mi)
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  • Atomic Silver 2021 Lexus RX 350 PremiumAtomic Silver 2021 Lexus RX 350 PremiumAtomic Silver 2021 Lexus RX 350 PremiumAtomic Silver 2021 Lexus RX 350 PremiumAtomic Silver 2021 Lexus RX 350 PremiumAtomic Silver 2021 Lexus RX 350 Premium

    $39,800

    38,028 mi.
    Est. $745/mo

    South Bay Lexus

    4.9
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    Torrance, CA (6 mi)
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  • Caviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 PremiumCaviar 2021 Lexus RX 350 Premium

    $35,900

    67,839 mi.
    Est. $672/mo

    South Bay Lexus

    4.9
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    Torrance, CA (6 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $35,998

    37,395 mi.
    Est. $674/mo

    CarMax Capitol Expressway

    4.2
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    $99 delivery to Torrance, CA (2 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $39,998

    29,829 mi.
    Est. $748/mo

    CarMax Modesto

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    $99 delivery to Torrance, CA (2 mi)
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  • Atomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 Base

    $37,999

    44,112 mi.
    Est. $711/mo

    Crown Lexus

    4.7
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    Ontario, CA (49 mi)
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  • Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350Black 2021 Lexus RX 350

    $27,998

    101,673 mi.
    Est. $524/mo

    CarMax Norco

    4.5
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    Norco, CA (47 mi)
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  • Nebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 PremiumNebula Gray Pearl 2021 Lexus RX 350 Premium

    $40,995

    33,849 mi.
    Est. $767/mo

    STG Auto Group of Montclair

    2.8
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    Montclair, CA (42 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $45,795

    $200
    10,726 mi.
    Est. $857/mo

    Tustin Lexus

    4.8
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    Tustin, CA (35 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $29,899

    $700
    73,643 mi.
    Est. $559/mo

    California Motors Direct

    4.2
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    Santa Ana, CA (31 mi)
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  • $37,574

    52,841 mi.
    Est. $703/mo

    Tustin Lexus

    4.8
    Check Availability
    Tustin, CA (35 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $60,940
2025 Lexus RX 350 $54,322 9 Good deals
2024 Lexus RX 350 $49,570 18 Good deals
2023 Lexus RX 350 $46,144 20 Good deals
2022 Lexus RX 350 $39,080 3 Good deals
2017 Lexus RX 350 $24,418 8 Good deals

About the 2021 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus RX 350
FAQs

How much does the 2021 Lexus RX 350 cost?

The 2021 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 RX 350 is $36,243, with pricing starting at $22,500.

What is the MPG of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus RX 350?

The 2021 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2021 Lexus RX 350 reliable?

The 2021 Lexus RX 350 has an average reliability rating of 4.8 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 RX 350 owners.

Is the 2021 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2021 Lexus RX 350.

(63 reviews)
Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Ratings (63 reviews)

88% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.7
Interior
4.7
Performance
4.7
Value
4.6
Exterior
4.6
Reliability
4.8
Trims

RX 350 (2 styles)

Style
RX 350 AWD RX 350 FWD
Inventory price
Starting at $46,620 Starting at $45,220
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $48,700 Starting at $50,100
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling AWD RX 350 F SPORT Handling FWD
Inventory price
Starting at $52,500 Starting at $51,100
Combined MPG
22 23
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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