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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $37,488

    76,205 mi.
    Est. $681/mo

    Stream Auto Outlet Valley Stream

    4.3
    Check Availability
    Valley Stream, NY (27 mi)

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  • Caviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 PremiumCaviar 2022 Lexus RX 350 Premium

    $41,495

    56,702 mi.
    Est. $754/mo

    DARCARS Lexus of Greenwich

    4.5
    Check Availability
    Greenwich, CT (24 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $38,997

    35,091 mi.
    Est. $709/mo

    Tri-County Lexus

    4.8
    Check Availability
    Little Falls, NJ (9 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $44,173

    24,987 mi.
    Est. $803/mo

    New Country Lexus of Great Neck

    4.4
    Check Availability
    Great Neck, NY (22 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $41,800

    29,267 mi.
    Est. $760/mo

    MajorWorld Chevy

    3.9
    Check Availability
    Long Island City, NY (16 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $38,777

    $767
    38,322 mi.
    Est. $705/mo

    Salerno Duane Chrysler Jeep Dodge Ram

    4.6
    Check Availability
    Summit, NJ (22 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $33,990

    74,362 mi.
    Est. $618/mo

    Auto Lux

    3.4
    Check Availability
    Elmont, NY (26 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT AppearanceUltra White 2022 Lexus RX 350 F SPORT Appearance

    $36,796

    49,712 mi.
    Est. $669/mo

    Carz4Us Pine Brook

    3.5
    Check Availability
    Pine Brook, NJ (16 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT AppearanceCaviar 2022 Lexus RX 350 F SPORT Appearance

    $35,990

    33,683 mi.
    Est. $654/mo

    Auto Lux

    3.4
    Check Availability
    Elmont, NY (26 mi)
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  • Gray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 Base

    $44,500

    13,000 mi.
    Est. $809/mo

    Private seller: Bekhruz

    Contact Seller
    New York, NY (25 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $41,498

    48,999 mi.
    Est. $754/mo

    Prestige Lexus of Ramsey

    4.6
    Check Availability
    Ramsey, NJ (10 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $32,995

    82,756 mi.
    Est. $600/mo

    Victory Mitsubishi

    3.4
    Check Availability
    Bronx, NY (14 mi)
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  • Nightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT AppearanceNightfall Mica 2022 Lexus RX 350 F SPORT Appearance

    $37,495

    57,748 mi.
    Est. $682/mo

    Victory Mitsubishi

    3.4
    Check Availability
    Bronx, NY (14 mi)
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  • Caviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 BaseCaviar 2022 Lexus RX 350 Base

    $32,995

    79,356 mi.
    Est. $600/mo

    Victory Mitsubishi

    3.4
    Check Availability
    Bronx, NY (14 mi)
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  • Caviar 2022 Lexus RX 350 Base

    $39,993

    46,212 mi.
    Est. $727/mo

    Cartopia 46

    3.7
    Check Availability
    Elmwood Park, NJ (5 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    Not Priced

    41,192 mi.
    Est. $0/mo

    Northstar Kia

    4.5
    Check Availability
    Woodside, NY (16 mi)
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  • $45,175

    28,680 mi.
    Est. $821/mo

    Lexus of Freeport

    4.7
    Check Availability
    Rockville Centre, NY (30 mi)
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  • Black 2022 Lexus RX 350 L LuxuryBlack 2022 Lexus RX 350 L LuxuryBlack 2022 Lexus RX 350 L LuxuryBlack 2022 Lexus RX 350 L LuxuryBlack 2022 Lexus RX 350 L LuxuryBlack 2022 Lexus RX 350 L Luxury

    $43,998

    65,559 mi.
    Est. $800/mo

    CarMax Independence Boulevard

    Check Availability
    $299 delivery to Wayne, NJ (11 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $43,990

    29,766 mi.
    Est. $800/mo

    Bentley Indianapolis

    4.2
    Check Availability
    $1,114 delivery from Indianapolis, IN (637 mi)
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  • Caviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT HandlingCaviar 2022 Lexus RX 350 F SPORT Handling

    $41,380

    55,163 mi.
    Est. $752/mo

    Auto Hub

    4.6
    Check Availability
    North Brunswick, NJ (43 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $43,173

    19,146 mi.
    Est. $785/mo

    BMW of Freeport

    4.9
    Check Availability
    Freeport, NY (32 mi)
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  • Red 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 BaseRed 2022 Lexus RX 350 Base

    $34,999

    38,564 mi.
    Est. $636/mo

    G-Motors of Old Bridge

    4.3
    Check Availability
    Old Bridge, NJ (37 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 Base

    $39,995

    50,202 mi.
    Est. $727/mo

    Johnstons Toyota

    4.9
    Check Availability
    New Hampton, NY (37 mi)
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  • Caviar 2022 Lexus RX 350 Base

    $43,990

    22,649 mi.
    Est. $800/mo

    BMW of Freehold

    4.8
    Check Availability
    Freehold, NJ (48 mi)
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  • $41,995

    36,958 mi.
    Est. $763/mo

    Land Rover Princeton

    5.0
    Check Availability
    Princeton, NJ (49 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,336 2 Good deals
2025 Lexus RX 350 $52,646 5 Great deals
2024 Lexus RX 350 $48,263 9 Great deals
2023 Lexus RX 350 $45,665 9 Great deals
2021 Lexus RX 350 $35,453 7 Good deals
2020 Lexus RX 350 $31,875 5 Great deals
2018 Lexus RX 350 $27,128 6 Good deals
2017 Lexus RX 350 $23,217 7 Good deals
2016 Lexus RX 350 $20,731 4 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $41,194, with pricing starting at $27,790.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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