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  • Nebula Gray Pearl 2022 Lexus RX 350 Base

    $37,590

    61,570 mi.
    Est. $699/mo

    AutoNation Chrysler Jeep Broadway

    4.4
    Check Availability
    Littleton, CO (18 mi)

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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $32,201

    $800
    125,892 mi.
    Est. $598/mo

    Stevinson Lexus of Frederick

    4.8
    Check Availability
    Longmont, CO (18 mi)
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  • Gray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 BaseGray 2022 Lexus RX 350 Base

    $40,532

    62,945 mi.
    Est. $753/mo

    Rocky Mountain Eurosport Parker

    4.8
    Check Availability
    Parker, CO (28 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $41,290

    61,416 mi.
    Est. $767/mo

    Lexus of Greenwood Village

    4.3
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    Greenwood Village, CO (19 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $41,801

    $200
    59,866 mi.
    Est. $777/mo

    Stevinson Lexus of Frederick

    4.8
    Check Availability
    Longmont, CO (18 mi)
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  • Nightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 BaseNightfall Mica 2022 Lexus RX 350 Base

    $37,201

    85,080 mi.
    Est. $691/mo

    Porsche Littleton

    4.9
    Check Availability
    Littleton, CO (19 mi)
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  • Silver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 LSilver 2022 Lexus RX 350 L

    $42,998

    43,275 mi.
    Est. $799/mo

    CarMax Salt Lake (South Jordan)

    4.3
    Check Availability
    Free delivery to Federal Heights, CO (2 mi)
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  • White 2022 Lexus RX 350 BaseWhite 2022 Lexus RX 350 BaseWhite 2022 Lexus RX 350 BaseWhite 2022 Lexus RX 350 BaseWhite 2022 Lexus RX 350 BaseWhite 2022 Lexus RX 350 Base

    $44,788

    41,262 mi.
    Est. $832/mo

    DallasLeaseReturns.com

    5.0
    Check Availability
    $992 delivery from Dallas, TX (662 mi)
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  • Silver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 BaseSilver 2022 Lexus RX 350 Base

    $42,000

    50,608 mi.
    Est. $781/mo

    Mercedes-Benz of Albuquerque

    4.7
    Check Availability
    Albuquerque, NM (335 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT AppearanceAtomic Silver 2022 Lexus RX 350 F SPORT Appearance

    $45,000

    41,813 mi.
    Est. $836/mo

    Lexus of Omaha

    4.9
    Check Availability
    Omaha, NE (478 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $46,000

    $400
    23,198 mi.
    Est. $855/mo

    Corwin Toyota of Bellevue

    4.5
    Check Availability
    Bellevue, NE (487 mi)
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  • Grecian Water 2022 Lexus RX 350 F SPORT HandlingGrecian Water 2022 Lexus RX 350 F SPORT HandlingGrecian Water 2022 Lexus RX 350 F SPORT HandlingGrecian Water 2022 Lexus RX 350 F SPORT HandlingGrecian Water 2022 Lexus RX 350 F SPORT HandlingGrecian Water 2022 Lexus RX 350 F SPORT Handling

    $43,281

    $720
    44,620 mi.
    Est. $804/mo

    Genesis of Lindon

    4.7
    Check Availability
    Lindon, UT (356 mi)
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  • Nightfall Mica 2022 Lexus RX 350 F SPORT HandlingNightfall Mica 2022 Lexus RX 350 F SPORT HandlingNightfall Mica 2022 Lexus RX 350 F SPORT HandlingNightfall Mica 2022 Lexus RX 350 F SPORT HandlingNightfall Mica 2022 Lexus RX 350 F SPORT HandlingNightfall Mica 2022 Lexus RX 350 F SPORT Handling

    $47,891

    38,536 mi.
    Est. $890/mo

    Eddy's Volkswagen

    1.9
    Check Availability
    Wichita, KS (449 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $44,750

    $150
    59,775 mi.
    Est. $832/mo

    Sandia BMW MINI

    4.8
    Check Availability
    Albuquerque, NM (340 mi)
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  • Caviar 2022 Lexus RX 350 BASECaviar 2022 Lexus RX 350 BASECaviar 2022 Lexus RX 350 BASECaviar 2022 Lexus RX 350 BASECaviar 2022 Lexus RX 350 BASECaviar 2022 Lexus RX 350 BASE

    $43,800

    $3.8K
    25,148 mi.
    Est. $814/mo

    Long McArthur Ford

    4.3
    Check Availability
    Salina, KS (405 mi)
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  • Atomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 BaseAtomic Silver 2022 Lexus RX 350 Base

    $45,900

    29,145 mi.
    Est. $853/mo

    Classic Motor Cars of Lubbock

    Check Availability
    Lubbock, TX (471 mi)
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  • Black 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 BaseBlack 2022 Lexus RX 350 Base

    $35,989

    26,116 mi.
    Est. $669/mo

    The Internet Car Lot

    4.1
    Check Availability
    Omaha, NE (483 mi)
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  • $40,992

    48,611 mi.
    Est. $762/mo

    Sid Dillon Nissan

    Check Availability
    Lincoln, NE (445 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 PremiumNebula Gray Pearl 2022 Lexus RX 350 Premium

    Not Priced

    31,834 mi.
    Est. $0/mo

    Lexus of Wichita

    4.7
    Check Availability
    Wichita, KS (448 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $63,746
2023 Lexus RX 350 $47,780 14 Good deals

About the 2022 Lexus RX 350

Basics

Base shown (base trim).

Seating
5
Door count
4
Drivetrain
Front-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2022 Lexus RX 350
FAQs

How much does the 2022 Lexus RX 350 cost?

The 2022 Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2022 RX 350 is $40,949, with pricing starting at $26,995.

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:


Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the Cars.com consumer ratings for the 2022 Lexus RX 350.

(13 reviews)
Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Ratings (13 reviews)

61% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
4.6
Interior
4.5
Performance
3.8
Value
3.5
Exterior
4.7
Reliability
3.9
Trims

RX 350 (2 styles)

Style
RX 350 FWD RX 350 AWD
Inventory price
Starting at $45,920 Starting at $47,320
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Appearance (2 styles)

Style
RX 350 F SPORT Appearance FWD RX 350 F SPORT Appearance AWD
Inventory price
Starting at $49,400 Starting at $50,800
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)

RX 350 F SPORT Handling (2 styles)

Style
RX 350 F SPORT Handling FWD RX 350 F SPORT Handling AWD
Inventory price
Starting at $51,800 Starting at $53,200
Combined MPG
23 22
Engine
295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 295.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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