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  • Ultra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F Sport

    $25,708

    104,238 mi.
    Est. $481/mo

    Fox Toyota

    3.8
    Check Availability
    Clinton, TN (19 mi)

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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $37,894

    107,888 mi.
    Est. $709/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Cloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 Base

    $48,766

    $1.1K
    10,542 mi.
    Est. $912/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Caviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 Premium

    $55,995

    13,986 mi.
    Est. $1,048/mo

    Grayson BMW

    4.8
    Check Availability
    Knoxville, TN (10 mi)
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  • Silver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 Base

    $35,985

    58,086 mi.
    Est. $673/mo

    Ted Russell Ford Kingston Pike

    4.6
    Check Availability
    Knoxville, TN (13 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $47,908

    31,700 mi.
    Est. $896/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $39,995

    64,860 mi.
    Est. $748/mo

    Grayson BMW

    4.8
    Check Availability
    Knoxville, TN (10 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $41,979

    14,745 mi.
    Est. $785/mo

    Harper INFINITI

    Check Availability
    Knoxville, TN (11 mi)
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  • Nightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 Premium

    $49,913

    19,543 mi.
    Est. $934/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $41,598

    51,512 mi.
    Est. $778/mo

    Harper Jaguar Alfa Romeo Maserati

    4.9
    Check Availability
    Knoxville, TN (11 mi)
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  • Copper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 Premium

    $52,986

    8,435 mi.
    Est. $991/mo

    AutoNation Honda West Knoxville

    4.8
    Check Availability
    Knoxville, TN (11 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $46,584

    $1.3K
    26,834 mi.
    Est. $872/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Dark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 Base

    $15,995

    125,358 mi.
    Est. $299/mo

    Auto Locators

    Check Availability
    Louisville, TN (21 mi)
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  • Iridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 Base

    $49,883

    $984
    12,765 mi.
    Est. $933/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Ultra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT Handling

    $54,975

    29,625 mi.
    Est. $1,029/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Smoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 Base

    $13,900

    110,817 mi.
    Est. $260/mo

    Knox Drives

    Check Availability
    Knoxville, TN (22 mi)
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  • $51,801

    31,962 mi.
    Est. $969/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • $24,884

    112,208 mi.
    Est. $466/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • $32,453

    64,716 mi.
    Est. $607/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (10 mi)
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  • Deep Sea Mica 2015 Lexus RX 350 Base

    $14,255

    167,771 mi.
    Est. $267/mo

    Rick McGills Airport Toyota

    4.7
    Check Availability
    Alcoa, TN (20 mi)
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  • Blue 2017 Lexus RX 350Blue 2017 Lexus RX 350Blue 2017 Lexus RX 350Blue 2017 Lexus RX 350Blue 2017 Lexus RX 350Blue 2017 Lexus RX 350

    $29,998

    43,937 mi.
    Est. $561/mo

    CarMax Columbia

    Check Availability
    $149 delivery to Knoxville, TN (9 mi)
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  • Nightfall Mica 2025 Lexus RX 350 BaseNightfall Mica 2025 Lexus RX 350 BaseNightfall Mica 2025 Lexus RX 350 BaseNightfall Mica 2025 Lexus RX 350 BaseNightfall Mica 2025 Lexus RX 350 BaseNightfall Mica 2025 Lexus RX 350 Base

    $48,018

    $5.8K
    6,474 mi.
    Est. $898/mo

    Mercedes-Benz of Buckhead

    Check Availability
    $399 delivery from Atlanta, GA (148 mi)
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  • Eminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 BaseEminent White Pearl 2021 Lexus RX 350 Base

    $43,991

    44,708 mi.
    Est. $823/mo

    Toyota of Cleveland

    4.9
    Check Availability
    McDonald, TN (68 mi)
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  • Matador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 Premium

    $54,499

    $2.1K
    30,600 mi.
    Est. $1,020/mo

    Rusty Wallace Cadillac GMC KIA

    Check Availability
    Morristown, TN (60 mi)
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  • Atomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 Base

    $33,990

    70,518 mi.
    Est. $636/mo

    Marlar Auto Mart South

    Check Availability
    Oneida, TN (40 mi)
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  • Matador Red Mica 2023 Lexus RX 350 Premium

    $52,544

    19,842 mi.
    Est. $983/mo

    Tarr Chevrolet

    4.3
    Check Availability
    Jefferson City, TN (47 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $67,591

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $35,039, with pricing starting at $2,500.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2011 to 2026.

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