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  • Matador Red Mica 2025 Lexus RX 350 PremiumMatador Red Mica 2025 Lexus RX 350 PremiumMatador Red Mica 2025 Lexus RX 350 PremiumMatador Red Mica 2025 Lexus RX 350 PremiumMatador Red Mica 2025 Lexus RX 350 PremiumMatador Red Mica 2025 Lexus RX 350 Premium

    $55,875

    4,714 mi.
    Est. $1,045/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 BaseNebula Gray Pearl 2022 Lexus RX 350 Base

    $40,378

    64,863 mi.
    Est. $756/mo

    Grayson BMW

    4.8
    Check Availability
    Knoxville, TN (23 mi)
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  • Matador Red Mica 2023 Lexus RX 350 PremiumMatador Red Mica 2023 Lexus RX 350 PremiumMatador Red Mica 2023 Lexus RX 350 PremiumMatador Red Mica 2023 Lexus RX 350 PremiumMatador Red Mica 2023 Lexus RX 350 PremiumMatador Red Mica 2023 Lexus RX 350 Premium

    $51,317

    $280
    19,842 mi.
    Est. $960/mo

    Tarr Chevrolet

    4.4
    Check Availability
    Jefferson City, TN (24 mi)
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  • Dark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 Base

    $14,995

    $1K
    125,358 mi.
    Est. $281/mo

    Auto Locators

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    Louisville, TN (13 mi)
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  • Nebula Gray Pearl 2017 Lexus RX 350Nebula Gray Pearl 2017 Lexus RX 350Nebula Gray Pearl 2017 Lexus RX 350Nebula Gray Pearl 2017 Lexus RX 350Nebula Gray Pearl 2017 Lexus RX 350Nebula Gray Pearl 2017 Lexus RX 350

    $25,790

    110,394 mi.
    Est. $483/mo

    Mercedes-Benz of Knoxville

    3.5
    Check Availability
    Knoxville, TN (22 mi)
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  • Caviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium Plus

    $51,969

    28,760 mi.
    Est. $972/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350White 2021 Lexus RX 350

    $42,998

    32,058 mi.
    Est. $805/mo

    CarMax Knoxville

    4.2
    Check Availability
    Knoxville, TN (24 mi)
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  • Caviar 2020 Lexus RX 350 BaseCaviar 2020 Lexus RX 350 BaseCaviar 2020 Lexus RX 350 BaseCaviar 2020 Lexus RX 350 BaseCaviar 2020 Lexus RX 350 BaseCaviar 2020 Lexus RX 350 Base

    $41,668

    30,153 mi.
    Est. $780/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Nebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 PremiumNebula Gray Pearl 2023 Lexus RX 350 Premium

    $48,839

    23,504 mi.
    Est. $914/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Cloudburst Gray 2025 Lexus RX 350 LuxuryCloudburst Gray 2025 Lexus RX 350 LuxuryCloudburst Gray 2025 Lexus RX 350 LuxuryCloudburst Gray 2025 Lexus RX 350 LuxuryCloudburst Gray 2025 Lexus RX 350 LuxuryCloudburst Gray 2025 Lexus RX 350 Luxury

    $60,871

    14,971 mi.
    Est. $1,139/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Nightfall Mica 2024 Lexus RX 350 PremiumNightfall Mica 2024 Lexus RX 350 PremiumNightfall Mica 2024 Lexus RX 350 PremiumNightfall Mica 2024 Lexus RX 350 PremiumNightfall Mica 2024 Lexus RX 350 PremiumNightfall Mica 2024 Lexus RX 350 Premium

    $52,838

    20,412 mi.
    Est. $989/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Caviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium PlusCaviar 2023 Lexus RX 350 Premium Plus

    $49,926

    $984
    31,962 mi.
    Est. $934/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Deep Sea Mica 2015 Lexus RX 350 BaseDeep Sea Mica 2015 Lexus RX 350 BaseDeep Sea Mica 2015 Lexus RX 350 BaseDeep Sea Mica 2015 Lexus RX 350 BaseDeep Sea Mica 2015 Lexus RX 350 BaseDeep Sea Mica 2015 Lexus RX 350 Base

    $13,900

    167,772 mi.
    Est. $260/mo

    Rick McGills Airport Toyota

    4.7
    Check Availability
    Alcoa, TN (14 mi)
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  • Starfire Pearl 2010 Lexus RX 350 BaseStarfire Pearl 2010 Lexus RX 350 BaseStarfire Pearl 2010 Lexus RX 350 BaseStarfire Pearl 2010 Lexus RX 350 BaseStarfire Pearl 2010 Lexus RX 350 BaseStarfire Pearl 2010 Lexus RX 350 Base

    $9,725

    217,579 mi.
    Est. $182/mo

    Rusty Wallace Kia Alcoa

    4.7
    Check Availability
    Louisville, TN (13 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium PlusEminent White Pearl 2023 Lexus RX 350 Premium Plus

    $51,899

    18,449 mi.
    Est. $971/mo

    Harper Acura

    4.9
    Check Availability
    Knoxville, TN (22 mi)
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  • Silver/Gray 2019 Lexus RX 350 BaseSilver/Gray 2019 Lexus RX 350 BaseSilver/Gray 2019 Lexus RX 350 BaseSilver/Gray 2019 Lexus RX 350 BaseSilver/Gray 2019 Lexus RX 350 BaseSilver/Gray 2019 Lexus RX 350 Base

    $28,986

    85,443 mi.
    Est. $542/mo

    AutoNation Honda West Knoxville

    4.8
    Check Availability
    Knoxville, TN (22 mi)
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  • Copper Crest 2025 Lexus RX 350 PremiumCopper Crest 2025 Lexus RX 350 PremiumCopper Crest 2025 Lexus RX 350 PremiumCopper Crest 2025 Lexus RX 350 PremiumCopper Crest 2025 Lexus RX 350 PremiumCopper Crest 2025 Lexus RX 350 Premium

    $53,583

    14,611 mi.
    Est. $1,003/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • Black 2016 Lexus RX 350 F SportBlack 2016 Lexus RX 350 F Sport

    $18,995

    $2K
    160,653 mi.
    Est. $355/mo

    Auto Locators

    Check Availability
    Louisville, TN (13 mi)
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  • $6,099

    190,120 mi.
    Est. $114/mo

    Knox Drives

    Check Availability
    Knoxville, TN (18 mi)
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  • Black 2017 Lexus RX 350 V6 ENGINE PRIOR CERTIFIED PRE-OWNED GREAT RELIABIL

    $25,594

    88,220 mi.
    Est. $479/mo

    Car Nation LLC

    3.9
    Check Availability
    Knoxville, TN (23 mi)
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  • $55,582

    10,095 mi.
    Est. $1,040/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • $43,942

    43,895 mi.
    Est. $822/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • $54,915

    25,487 mi.
    Est. $1,028/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
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  • $49,875

    67,305 mi.
    Est. $933/mo

    Lexus of Knoxville

    4.1
    Check Availability
    Knoxville, TN (23 mi)
    Quick view
  • Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350Burgundy 2020 Lexus RX 350

    $37,998

    38,840 mi.
    Est. $711/mo

    CarMax Tupelo

    Check Availability
    $199 delivery to Knoxville, TN (24 mi)
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  • White 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT HandlingWhite 2022 Lexus RX 350 F-SPORT Handling

    $36,998

    86,727 mi.
    Est. $692/mo

    CarMax Greenville NC

    5.0
    Check Availability
    $149 delivery to Knoxville, TN (24 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $64,494

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $34,977, with pricing starting at $4,400.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2007 to 2026.

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