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  • Ultra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT Handling

    $54,975

    29,625 mi.
    Est. $1,029/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Atomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 BaseAtomic Silver 2020 Lexus RX 350 Base

    $27,498

    120,054 mi.
    Est. $515/mo

    Toyota Knoxville

    4.5
    Check Availability
    Knoxville, TN (23 mi)
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  • Copper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 PremiumCopper Crest 2024 Lexus RX 350 Premium

    $52,987

    $500
    8,435 mi.
    Est. $991/mo

    AutoNation Honda West Knoxville

    4.8
    Check Availability
    Knoxville, TN (22 mi)
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  • Silver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 BaseSilver 2020 Lexus RX 350 Base

    $35,995

    58,086 mi.
    Est. $674/mo

    Ted Russell Ford Kingston Pike

    4.6
    Check Availability
    Knoxville, TN (19 mi)
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  • Ultra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F SportUltra White 2017 Lexus RX 350 F Sport

    $25,908

    104,238 mi.
    Est. $485/mo

    Fox Toyota

    3.7
    Check Availability
    Clinton, TN (30 mi)
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  • Nebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT HandlingNebula Gray Pearl 2022 Lexus RX 350 F SPORT Handling

    $37,894

    107,888 mi.
    Est. $709/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Caviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 BaseCaviar 2021 Lexus RX 350 Base

    $41,981

    14,737 mi.
    Est. $786/mo

    Harper INFINITI

    Check Availability
    Knoxville, TN (22 mi)
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  • Cloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 BaseCloudburst Gray 2025 Lexus RX 350 Base

    $48,766

    $1.1K
    10,542 mi.
    Est. $912/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Eminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 BaseEminent White Pearl 2022 Lexus RX 350 Base

    $47,908

    31,700 mi.
    Est. $896/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Eminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 LuxuryEminent White Pearl 2023 Lexus RX 350 Luxury

    $51,615

    36,406 mi.
    Est. $966/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Ultra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT HandlingUltra White 2024 Lexus RX 350 F SPORT Handling

    $51,498

    37,690 mi.
    Est. $964/mo

    Harper Jaguar Alfa Romeo Maserati

    4.9
    Check Availability
    Knoxville, TN (22 mi)
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  • Caviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 PremiumCaviar 2025 Lexus RX 350 Premium

    $55,995

    13,986 mi.
    Est. $1,048/mo

    Grayson BMW

    4.8
    Check Availability
    Knoxville, TN (23 mi)
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  • Nightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 PremiumNightfall Mica 2023 Lexus RX 350 Premium

    $49,913

    19,543 mi.
    Est. $934/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Ultra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT HandlingUltra White 2022 Lexus RX 350 F SPORT Handling

    $46,584

    $1.3K
    26,834 mi.
    Est. $872/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Dark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 BaseDark Blue 2015 Lexus RX 350 Base

    $15,995

    125,358 mi.
    Est. $299/mo

    Auto Locators

    Check Availability
    Louisville, TN (13 mi)
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  • Smoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 BaseSmoky Granite Mica 2011 Lexus RX 350 Base

    $13,900

    110,817 mi.
    Est. $260/mo

    Knox Drives

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    Knoxville, TN (18 mi)
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  • Iridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 BaseIridium 2025 Lexus RX 350 Base

    $49,883

    $984
    12,765 mi.
    Est. $933/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • 2016 Lexus RX 3502016 Lexus RX 3502016 Lexus RX 3502016 Lexus RX 3502016 Lexus RX 3502016 Lexus RX 350

    $17,980

    151,496 mi.
    Est. $336/mo

    Iron Horse Auto LLC

    Check Availability
    Knoxville, TN (20 mi)
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  • $24,884

    112,208 mi.
    Est. $466/mo

    Lexus of Knoxville

    4.2
    Check Availability
    Knoxville, TN (23 mi)
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  • Matador Red Mica 2023 Lexus RX 350 Premium

    $51,544

    19,842 mi.
    Est. $964/mo

    Tarr Chevrolet

    4.3
    Check Availability
    Jefferson City, TN (24 mi)
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  • Atomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT HandlingAtomic Silver 2022 Lexus RX 350 F SPORT Handling

    $43,990

    $1K
    29,766 mi.
    Est. $823/mo

    Bentley Indianapolis

    4.2
    Check Availability
    $542 delivery from Indianapolis, IN (310 mi)
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  • Silver 2023 Lexus RX 350Silver 2023 Lexus RX 350Silver 2023 Lexus RX 350Silver 2023 Lexus RX 350Silver 2023 Lexus RX 350Silver 2023 Lexus RX 350

    $44,998

    18,336 mi.
    Est. $842/mo

    CarMax Gainesville Georgia

    Check Availability
    Free delivery to Knoxville, TN (24 mi)
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  • Matador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 PremiumMatador Red Mica 2024 Lexus RX 350 Premium

    $54,499

    $2.1K
    30,600 mi.
    Est. $1,020/mo

    Rusty Wallace Cadillac GMC KIA

    Check Availability
    Morristown, TN (37 mi)
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  • Atomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 BaseAtomic Silver 2021 Lexus RX 350 Base

    $33,990

    70,518 mi.
    Est. $636/mo

    Marlar Auto Mart South

    Check Availability
    Oneida, TN (63 mi)
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  • $30,122

    40,654 mi.
    Est. $564/mo

    Hyundai of Asheville

    4.9
    Check Availability
    Asheville, NC (72 mi)
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Lexus RX 350 prices by year

Model year Average price Deals
2026 Lexus RX 350 $67,273

About the Lexus RX 350

FAQs

How much does the Lexus RX 350 cost?

The Lexus RX 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for the RX 350 is $34,870, with pricing starting at $3,900.

What is the MPG of the Lexus RX 350?

The Lexus RX 350 with traditional internal combustion engine offers up to 22 MPG city and 29 MPG highway for a combined rating of 25 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle model year, trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the Lexus RX 350?

The Lexus RX 350 compares to and/or competes against the following vehicles:


What trim levels are available for the Lexus RX 350?

The Lexus RX 350 is available in the following trim levels:

What model years are available for the Lexus RX 350?

Available model years for Lexus RX 350 inventory range from 2011 to 2026.

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