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  • Iridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 BaseIridium 2021 Lexus IS 350 Base

    $39,203

    22,108 mi.
    Est. $683/mo

    AutoNation Ford Fort Worth

    4.4
    Check Availability
    Fort Worth, TX (30 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 Base

    $37,443

    60,769 mi.
    Est. $653/mo

    Grapevine Ford Lincoln

    4.4
    Check Availability
    Grapevine, TX (8 mi)
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  • Grecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 BaseGrecian Water 2021 Lexus IS 350 Base

    $44,680

    33,835 mi.
    Est. $779/mo

    Tom Clark Chevrolet

    Check Availability
    Denton, TX (14 mi)
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  • Infrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 BaseInfrared 2021 Lexus IS 350 Base

    $37,274

    $713
    59,938 mi.
    Est. $650/mo

    Reliable Chevrolet

    4.3
    Check Availability
    Richardson, TX (24 mi)
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  • Silver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 BaseSilver 2021 Lexus IS 350 Base

    $34,488

    78,223 mi.
    Est. $601/mo

    Autos of Dallas

    3.2
    Check Availability
    Plano, TX (20 mi)
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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $39,825

    $2.9K
    39,019 mi.
    Est. $694/mo

    Sewell Lexus of Dallas

    3.3
    Check Availability
    Dallas, TX (22 mi)
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  • $34,913

    94,434 mi.
    Est. $609/mo

    Sewell Lexus of Dallas

    3.3
    Check Availability
    Dallas, TX (22 mi)
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  • $39,410

    $502
    37,125 mi.
    Est. $687/mo

    Autobahn BMW Fort Worth

    4.3
    Check Availability
    Fort Worth, TX (24 mi)
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  • Ultra White 2021 Lexus IS 350 Base

    $45,997

    30,076 mi.
    Est. $802/mo

    Prosper Ford

    4.6
    Check Availability
    Prosper, TX (25 mi)
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  • Black 2021 Lexus IS 350 F-SportBlack 2021 Lexus IS 350 F-SportBlack 2021 Lexus IS 350 F-SportBlack 2021 Lexus IS 350 F-SportBlack 2021 Lexus IS 350 F-SportBlack 2021 Lexus IS 350 F-Sport

    $40,998

    51,042 mi.
    Est. $715/mo

    CarMax Amarillo

    4.5
    Check Availability
    $149 delivery to Denton, TX (10 mi)
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  • Silver 2021 Lexus IS 350 F-SportSilver 2021 Lexus IS 350 F-SportSilver 2021 Lexus IS 350 F-SportSilver 2021 Lexus IS 350 F-SportSilver 2021 Lexus IS 350 F-SportSilver 2021 Lexus IS 350 F-Sport

    $38,998

    46,440 mi.
    Est. $680/mo

    CarMax College Station

    4.6
    Check Availability
    $149 delivery to Denton, TX (10 mi)
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  • Caviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 BaseCaviar 2021 Lexus IS 350 Base

    $35,720

    63,525 mi.
    Est. $623/mo

    Lexus of Southwest Houston

    4.8
    Check Availability
    Houston, TX (250 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 Base

    $40,483

    $1.6K
    23,243 mi.
    Est. $706/mo

    Big Star Cadillac

    4.8
    Check Availability
    Friendswood, TX (267 mi)
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  • Cloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 BaseCloudburst Gray 2021 Lexus IS 350 Base

    $36,997

    $562
    74,474 mi.
    Est. $645/mo

    Northside Lexus

    4.9
    Check Availability
    Spring, TX (225 mi)
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  • $37,991

    64,298 mi.
    Est. $662/mo

    Scholfield Honda

    3.8
    Check Availability
    Wichita, KS (322 mi)
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Lexus IS 350 prices by year

Model year Average price Deals
2026 Lexus IS 350 $56,455 1 Good deal
2025 Lexus IS 350 $46,752 10 Good deals
2024 Lexus IS 350 $44,934 8 Good deals
2023 Lexus IS 350 $45,488 9 Great deals
2022 Lexus IS 350 $42,305 5 Good deals

About the 2021 Lexus IS 350

Basics

F Sport shown (base trim).

Seating
5
Door count
4
Drivetrain
Rear-wheel drive
Combined MPG
23
Transmission
8-Speed A/T
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
Side view of the 2021 Lexus IS 350
FAQs

How much does the 2021 Lexus IS 350 cost?

The 2021 Lexus IS 350 price depends on several factors, including the trim level, optional features, mileage, vehicle history and location. The nationwide average price for a 2021 IS 350 is $38,337, with pricing starting at $29,690.

What is the MPG of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 offers up to 20 MPG in city driving and 28 MPG on the highway for a combined rating of 23 MPG.

These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on the selected vehicle trim, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2021 Lexus IS 350?

The 2021 Lexus IS 350 compares to and/or competes against the following vehicles:


  • Mitsubishi Lancer
  • Lexus IS 500
  • Lexus IS 300
  • Genesis G70
  • BMW M340
  • Acura TLX

Is the 2021 Lexus IS 350 reliable?

The 2021 Lexus IS 350 has an average reliability rating of 5 out of 5 according to Cars.com consumers. Find real-world reliability insights within consumer reviews from 2021 IS 350 owners.

Is the 2021 Lexus IS 350 a good sedan?

Below are the Cars.com consumer ratings for the 2021 Lexus IS 350.

(2 reviews)
Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Ratings (2 reviews)

100% of drivers recommend this car

Rating breakdown (out of 5):
Comfort
5.0
Interior
4.5
Performance
5.0
Value
4.5
Exterior
5.0
Reliability
5.0
Trims

IS 350 F SPORT (2 styles)

Style
IS 350 F SPORT RWD IS 350 F SPORT AWD
Inventory price
Starting at $42,950 Starting at $44,950
Combined MPG
23 22
Engine
311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel) 311.0-hp, 3.5-liter, V6 Cylinder Engine (Gasoline Fuel)
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